PCIDB

KNApSAcK Metabolite C00001569

Metabolite

KNApSAcK Entry

id C00001569
Name Crinamine
CAS RN 639-41-8
Standard InChI InChI=1S/C17H19NO4/c1-20-11-2-3-17-12-6-14-13(21-9-22-14)4-10(12)7-18(8-16(17)19)15(17)5-11/h2-4,6,11,15-16,19H,5,7-9H2,1H3/t11-,15-,16-,17-/m0/s1
Standard InChI (Main Layer) InChI=1S/C17H19NO4/c1-20-11-2-3-17-12-6-14-13(21-9-22-14)4-10(12)7-18(8-16(17)19)15(17)5-11/h2-4,6,11,15-16,19H,5,7-9H2,1H3

Cluster

Phytochemical cluster No. 4
KCF-S cluster No. 103

Link

ChEMBL

By standard InChI CHEMBL516991
By standard InChI Main Layer CHEMBL401114 CHEMBL516991 CHEMBL1172810 CHEMBL1221865 CHEMBL1551610 CHEMBL1995397

KEGG

By LinkDB C08525

CTD

By CAS RN C411129

Human Protein / Gene in interaction

5 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q16637 Survival motor neuron protein Unclassified protein CHEMBL1551610 CHEMBL1613842 (1)
4 / 2
P28482 Mitogen-activated protein kinase 1 Erk CHEMBL1551610 CHEMBL1613808 (1)
0 / 0
P22303 Acetylcholinesterase Hydrolase CHEMBL401114 CHEMBL1221865 CHEMBL925438 (1) CHEMBL1227598 (1)
1 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL1551610 CHEMBL1614108 (1) CHEMBL1613886 (1)
0 / 1
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme CHEMBL1551610 CHEMBL1614364 (1)
1 / 1

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (6)

OMIM preferred title UniProt
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#112100 Yt blood group antigen P22303

KEGG DISEASE (3)

KEGG disease name UniProt
H00036 Osteosarcoma P08684 (marker)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
Q16637 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)