Species

KNApSAcK Entry

Organism name Brunsvigia josephinae
Genus Brunsvigia
Family Amaryllidaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Brunsvigia
Linked NCBI taxonomy ID 82217
Linked level genus

Family

Family in NCBI taxonomy Amaryllidaceae
ID 4668

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Liliopsida
ID 4447

Metabolite list (12)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00001561 External link 512 Ambelline
/ (-)-Ambelline
CHEMBL1173110
CHEMBL1600436
CHEMBL1980252
1 / 0 / 1 No. 103 No. 4
C00001569 External link 512 Crinamine
CHEMBL401114
CHEMBL516991
CHEMBL1172810
CHEMBL1221865
CHEMBL1551610
CHEMBL1995397
C411129
5 / 6 / 3 No. 103 No. 4
C00024354 External link 512 Yemenine A
/ 3-Acetylhamayne
/ 3-O-Acetylhamayne
/ Hamayne 3-acetate
/ O-Demethylcrinamine 3-acetate
CHEMBL469438
No. 103 No. 4
C00024371 External link 512 Buphanisine
CHEMBL512945
No. 103 No. 4
C00024384 External link 512 Crinine
/ Crinidine
CHEMBL469648
CHEMBL1221864
CHEMBL1971343
3 / 1 / 0 No. 103 No. 4
C00024392 External link 512 Hamayne
/ Bulbispermine
CHEMBL250055
CHEMBL511614
CHEMBL1993537
CHEMBL2087241
No. 103 No. 4
C00027662 External link 512 11-O-Acetylambelline
No. 103 No. 4
C00027975 External link 512 Brunsbelline
CHEMBL1173110
CHEMBL1600436
CHEMBL1980252
1 / 0 / 1 No. 103 No. 4
C00027991 External link 512 Buphanidrine
CHEMBL2009061
CHEMBL2146603
No. 103 No. 4
C00024437 External link 512 Sternbergine
No. 633 No. 4
C00024440 External link 512 Undulatin
/ Undulatine
No. 830 No. 4
C00024395 External link 512 Hippadine
/ Pratorine
CHEMBL1922244
C039688
No. 1055

Human Protein / Gene in interactions

7 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001561 C00001569 C00027975 0 / 1
P22303 Acetylcholinesterase Hydrolase C00001569 C00024384 1 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00001569 0 / 0
P11388 DNA topoisomerase 2-alpha Isomerase C00024384 0 / 0
Q16637 Survival motor neuron protein Unclassified protein C00001569 4 / 1
P11387 DNA topoisomerase 1 Isomerase C00024384 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00001569 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (6)

OMIM preferred title UniProt
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#112100 Yt blood group antigen P22303

KEGG DISEASE (3)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)