PCIDB

KNApSAcK Metabolite C00001714

Metabolite

KNApSAcK Entry

id C00001714
Name Eburnamonine
CAS RN 4880-88-0
Standard InChI InChI=1S/C19H22N2O/c1-2-19-9-5-10-20-11-8-14-13-6-3-4-7-15(13)21(16(22)12-19)17(14)18(19)20/h3-4,6-7,18H,2,5,8-12H2,1H3/t18-,19+/m1/s1
Standard InChI (Main Layer) InChI=1S/C19H22N2O/c1-2-19-9-5-10-20-11-8-14-13-6-3-4-7-15(13)21(16(22)12-19)17(14)18(19)20/h3-4,6-7,18H,2,5,8-12H2,1H3

Cluster

Phytochemical cluster No. 4
KCF-S cluster No. 502

Link

ChEMBL

By standard InChI CHEMBL1892145
By standard InChI Main Layer CHEMBL1318553 CHEMBL1553441 CHEMBL1733074 CHEMBL1892145

KEGG

By LinkDB C09149

CTD

By CAS RN

Species

Summary

Plant class

class name count
asterids 2

Family

family name count
Apocynaceae 2

List (2)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Hunteria eburnea Pichon. 141570 Apocynaceae asterids Viridiplantae
Vinca minor 60093 Apocynaceae asterids Viridiplantae

Human Protein / Gene in interaction

14 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 CHEMBL1318553 CHEMBL1614110 (3) CHEMBL1741321 (2)
1 / 0
Q99700 Ataxin-2 Unclassified protein CHEMBL1892145 CHEMBL2114784 (1)
1 / 1
P02545 Prelamin-A/C Unclassified protein CHEMBL1318553 CHEMBL1614544 (1)
11 / 10
P16473 Thyrotropin receptor Glycohormone receptor CHEMBL1318553 CHEMBL1614281 (1) CHEMBL1614361 (1)
3 / 2
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 CHEMBL1318553 CHEMBL1614027 (1) CHEMBL1741325 (2)
0 / 1
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein CHEMBL1733074 CHEMBL1794584 (1)
2 / 0
O75496 Geminin Unclassified protein CHEMBL1318553 CHEMBL1892145 CHEMBL2114843 (2) CHEMBL2114780 (2)
0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor CHEMBL1733074 CHEMBL1892145 CHEMBL2114788 (2)
0 / 0
Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G Enzyme CHEMBL1733074 CHEMBL1892145 CHEMBL1963863 (2)
0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 CHEMBL1318553 CHEMBL1741322 (2)
0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 CHEMBL1318553 CHEMBL1613777 (2) CHEMBL1741323 (2)
1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL1318553 CHEMBL1553441 CHEMBL1614108 (3) CHEMBL1613886 (3)
CHEMBL1741324 (2)
0 / 1
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme CHEMBL1733074 CHEMBL1738442 (1)
0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme CHEMBL1892145 CHEMBL2354311 (1)
1 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (20)

OMIM preferred title UniProt
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#114500 Colorectal cancer; crc P84022
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#137800 Glioma susceptibility 1; glm1 O75874
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#275210 Restrictive dermopathy, lethal P02545
#183090 Spinocerebellar ataxia 2; sca2 Q99700

KEGG DISEASE (16)

KEGG disease name UniProt
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)