KNApSAcK Metabolite C00018233
Metabolite
KNApSAcK Entry
| id | C00018233 |
|---|---|
| Name | Aboren / SF 837 / Myoxam / Midecin / Momicine / Macropen / SF 837A1 / YL 704B1 / Normicina / Medemycin / Rubimycin / NSC 154011 / Midecamycin / Mydecamycin / Medemycin A1 / Turimycin P3 / Espinomycin A / Mydecamycin A1 / Medecamycin A1 / Midecamycin A1 / Platenomycin B1 / Antibiotic SF 837 / Antibiotic YL 704B1 / Antibiotic SF 837A1 |
| CAS RN | 35457-80-8 |
| Standard InChI | InChI=1S/C41H67NO15/c1-11-30(45)54-29-21-32(47)51-24(4)16-14-13-15-17-28(44)23(3)20-27(18-19-43)37(38(29)50-10)57-40-35(48)34(42(8)9)36(25(5)53-40)56-33-22-41(7,49)39(26(6)52-33)55-31(46)12-2/h13-15,17,19,23-29,33-40,44,48-49H,11-12,16,18,20-22H2,1-10H3/b14-13+,17-15+/t23-,24-,25-,26+,27+,28+,29-,33+,34-,35-,36-,37+,38?,39+,40+,41-/m1/s1 |
| Standard InChI (Main Layer) | InChI=1S/C41H67NO15/c1-11-30(45)54-29-21-32(47)51-24(4)16-14-13-15-17-28(44)23(3)20-27(18-19-43)37(38(29)50-10)57-40-35(48)34(42(8)9)36(25(5)53-40)56-33-22-41(7,49)39(26(6)52-33)55-31(46)12-2/h13-15,17,19,23-29,33-40,44,48-49H,11-12,16,18,20-22H2,1-10H3 |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 180 |
Link
ChEMBL
| By standard InChI | |
|---|---|
| By standard InChI Main Layer | CHEMBL444963 CHEMBL1305053 CHEMBL1436846 |
KEGG
| By LinkDB |
|---|
CTD
| By CAS RN | C026483 |
|---|
Species
Summary
Plant class
| class name | count |
|---|
Family
| family name | count |
|---|---|
| Streptomycetaceae | 1 |
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Streptomyces mycarofaciens No.510-19 | 1883 | Streptomycetaceae | Bacteria |
Human Protein / Gene in interaction
8 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | CHEMBL1436846 |
CHEMBL1741321
(1)
|
1 / 0 |
| O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | CHEMBL1436846 |
CHEMBL1614331
(1)
|
0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | CHEMBL1436846 |
CHEMBL1741325
(1)
|
0 / 1 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | CHEMBL1436846 |
CHEMBL1794467
(1)
|
0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | CHEMBL1436846 |
CHEMBL1741322
(1)
|
0 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | CHEMBL1305053 |
CHEMBL1738588
(1)
|
0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | CHEMBL1436846 |
CHEMBL1741323
(1)
|
1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | CHEMBL1436846 |
CHEMBL1741324
(1)
|
0 / 1 |
CTD interaction (2)
| compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
|---|---|---|---|---|---|---|---|
| C026483 | 8647 |
ABCB11
ABC16 BRIC2 BSEP PFIC-2 PFIC2 PGY4 SPGP |
ATP-binding cassette, sub-family B (MDR/TAP), member 11 | midecamycin results in decreased activity of ABCB11 protein |
decreases activity
|
protein |
15618715
|
| C026483 | 1244 |
ABCC2
ABC30 CMOAT DJS MRP2 cMRP |
ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | midecamycin results in decreased activity of ABCC2 protein |
decreases activity
|
protein |
15618715
|