Species

KNApSAcK Entry

Organism name Streptomyces mycarofaciens No.510-19
Genus Streptomyces
Family Streptomycetaceae
Kingdom Bacteria

NCBI taxonomy

Entry

Linked NCBI taxonomy name Streptomyces
Linked NCBI taxonomy ID 1883
Linked level genus

Family

Family in NCBI taxonomy Streptomycetaceae
ID 2062

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Bacteria
ID 2

Plant class

Plant class
ID

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00018233 External link 512 Aboren
/ SF 837
/ Myoxam
/ Midecin
/ Momicine
/ Macropen
/ SF 837A1
/ YL 704B1
/ Normicina
/ Medemycin
/ Rubimycin
/ NSC 154011
/ Midecamycin
/ Mydecamycin
/ Medemycin A1
/ Turimycin P3
/ Espinomycin A
/ Mydecamycin A1
/ Medecamycin A1
/ Midecamycin A1
/ Platenomycin B1
/ Antibiotic SF 837
/ Antibiotic YL 704B1
/ Antibiotic SF 837A1
CHEMBL444963
CHEMBL1305053
CHEMBL1436846
C026483
8 / 2 / 3 2 / 0 No. 180
C00018234 External link 512 Mydecamycin A3
/ Medecamycin A3
/ Midecamycin A3
/ Antibiotic SF 837A3
No. 180

Human Protein / Gene in interactions

8 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00018233 1 / 0
O75604 Ubiquitin carboxyl-terminal hydrolase 2 Enzyme C00018233 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00018233 0 / 1
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00018233 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00018233 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00018233 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00018233 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00018233 0 / 1

2 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
8647 ABCB11, ABC16, BRIC2, BSEP, PFIC-2, PFIC2, PGY4, SPGP ATP-binding cassette, sub-family B (MDR/TAP), member 11 C00018233
1244 ABCC2, ABC30, CMOAT, DJS, MRP2, cMRP ATP-binding cassette, sub-family C (CFTR/MRP), member 2 C00018233

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (2)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635

KEGG DISEASE (3)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)