PCIDB

KNApSAcK Metabolite C00002020

Metabolite

KNApSAcK Entry

id C00002020
Name Arecoline
CAS RN 63-75-2
Standard InChI InChI=1S/C8H13NO2/c1-9-5-3-4-7(6-9)8(10)11-2/h4H,3,5-6H2,1-2H3
Standard InChI (Main Layer) InChI=1S/C8H13NO2/c1-9-5-3-4-7(6-9)8(10)11-2/h4H,3,5-6H2,1-2H3

Cluster

Phytochemical cluster No. 1
KCF-S cluster No. 3405

Link

ChEMBL

By standard InChI CHEMBL7303
By standard InChI Main Layer CHEMBL7303

KEGG

By LinkDB C10129

CTD

By CAS RN D001115

Species

Summary

Plant class

class name count
Liliopsida 1

Family

family name count
Arecaceae 1

List (1)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Areca catechu 184783 Arecaceae Liliopsida Viridiplantae

Human Protein / Gene in interaction

15 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 CHEMBL7303 CHEMBL1741321 (2)
1 / 0
P49798 Regulator of G-protein signaling 4 Unclassified protein CHEMBL7303 CHEMBL1794499 (1)
2 / 0
P02545 Prelamin-A/C Unclassified protein CHEMBL7303 CHEMBL1614544 (1)
11 / 10
P10828 Thyroid hormone receptor beta NR1A2 CHEMBL7303 CHEMBL1613776 (1)
3 / 1
P08912 Muscarinic acetylcholine receptor M5 Acetylcholine receptor CHEMBL7303 CHEMBL684492 (1) CHEMBL683206 (1)
CHEMBL747137 (1) CHEMBL747159 (1)
CHEMBL748276 (1) CHEMBL923037 (1)
0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 CHEMBL7303 CHEMBL1741325 (2)
0 / 1
P08172 Muscarinic acetylcholine receptor M2 Acetylcholine receptor CHEMBL7303 CHEMBL684492 (1) CHEMBL683206 (1)
CHEMBL749205 (1) CHEMBL745482 (1)
CHEMBL744783 (1) CHEMBL748246 (1)
CHEMBL745634 (1) CHEMBL745647 (1)
CHEMBL748894 (1) CHEMBL748904 (1)
CHEMBL747480 (1) CHEMBL747481 (1)
CHEMBL751167 (1) CHEMBL848570 (1)
CHEMBL847458 (1) CHEMBL846393 (1)
CHEMBL923036 (1)
2 / 0
P11229 Muscarinic acetylcholine receptor M1 Acetylcholine receptor CHEMBL7303 CHEMBL684492 (1) CHEMBL683206 (1)
CHEMBL744231 (1) CHEMBL744234 (1)
CHEMBL744235 (1) CHEMBL744321 (1)
CHEMBL744325 (1) CHEMBL744326 (1)
CHEMBL744768 (1) CHEMBL744920 (1)
CHEMBL745687 (1) CHEMBL748279 (1)
CHEMBL744060 (1) CHEMBL744061 (1)
CHEMBL773336 (1) CHEMBL881931 (1)
CHEMBL848570 (1) CHEMBL846393 (1)
CHEMBL850283 (1) CHEMBL851333 (1)
CHEMBL923035 (1)
0 / 0
P20309 Muscarinic acetylcholine receptor M3 Acetylcholine receptor CHEMBL7303 CHEMBL684492 (1) CHEMBL683206 (1)
CHEMBL745482 (1) CHEMBL749054 (1)
CHEMBL746366 (1) CHEMBL746514 (1)
CHEMBL747819 (1) CHEMBL747822 (1)
CHEMBL872667 (1) CHEMBL752405 (1)
CHEMBL747474 (1)
1 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 CHEMBL7303 CHEMBL1741322 (2)
0 / 0
P08173 Muscarinic acetylcholine receptor M4 Acetylcholine receptor CHEMBL7303 CHEMBL684492 (1) CHEMBL683206 (1)
CHEMBL749231 (1) CHEMBL749238 (1)
CHEMBL749861 (1) CHEMBL749862 (1)
CHEMBL749863 (1) CHEMBL749864 (1)
CHEMBL745069 (1)
0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 CHEMBL7303 CHEMBL1741323 (2)
1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL7303 CHEMBL1741324 (2)
0 / 1
Q13951 Core-binding factor subunit beta Unclassified protein CHEMBL7303 CHEMBL1613933 (1)
0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein CHEMBL7303 CHEMBL1613933 (1)
1 / 6

CTD interaction (73)

compound gene gene name gene description interaction interaction type form reference
pmid
D001115 57491 AHRR
AHH
AHHR
bHLHe77
aryl-hydrocarbon receptor repressor Arecoline inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHRR mRNA] decreases reaction
/ increases expression
mRNA 17234337
D001115 10327 AKR1A1
ALDR1
ALR
ARM
DD3
aldo-keto reductase family 1, member A1 (aldehyde reductase) (EC:1.1.1.2) Arecoline results in decreased expression of AKR1A1 mRNA decreases expression
mRNA 17682004
D001115 223 ALDH9A1
ALDH4
ALDH7
ALDH9
E3
TMABADH
aldehyde dehydrogenase 9 family, member A1 (EC:1.2.1.3 1.2.1.19 1.2.1.47) Arecoline results in decreased expression of ALDH9A1 mRNA decreases expression
mRNA 17682004
D001115 328 APEX1
APE
APE1
APEN
APEX
APX
HAP1
REF1
APEX nuclease (multifunctional DNA repair enzyme) 1 (EC:4.2.99.18) Arecoline results in decreased expression of APEX1 mRNA decreases expression
mRNA 17682004
D001115 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 Arecoline results in decreased expression of BCL2 protein decreases expression
protein 22108589
D001115 672 BRCA1
BRCAI
BRCC1
BROVCA1
IRIS
PNCA4
PPP1R53
PSCP
RNF53
breast cancer 1, early onset Arecoline results in decreased expression of BRCA1 mRNA decreases expression
mRNA 17682004
D001115 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) Arecoline results in increased activity of CASP3 protein increases activity
protein 22108589
D001115 6352 CCL5
D17S136E
RANTES
SCYA5
SIS-delta
SISd
TCP228
eoCP
chemokine (C-C motif) ligand 5 Arecoline results in increased secretion of CCL5 protein increases secretion
protein 21297082
D001115 902 CCNH
CAK
p34
p37
cyclin H Arecoline results in decreased expression of CCNH mRNA decreases expression
mRNA 17682004
D001115 995 CDC25C
CDC25
PPP1R60
cell division cycle 25C (EC:3.1.3.48) [[Arecoline results in decreased expression of CDC25C] co-treated with [Arecoline results in increased expression of TP53]] results in decreased activity of CDK1 protein affects cotreatment
/ decreases activity
/ decreases expression
/ increases expression
22108589
D001115 995 CDC25C
CDC25
PPP1R60
cell division cycle 25C (EC:3.1.3.48) Arecoline results in decreased expression of CDC25C protein decreases expression
protein 22108589
D001115 983 CDK1
CDC2
CDC28A
P34CDC2
cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) Arecoline results in decreased activity of CDK1 protein decreases activity
protein 22108589
D001115 983 CDK1
CDC2
CDC28A
P34CDC2
cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) [[Arecoline results in decreased expression of CDC25C] co-treated with [Arecoline results in increased expression of TP53]] results in decreased activity of CDK1 protein affects cotreatment
/ decreases activity
/ decreases expression
/ increases expression
protein 22108589
D001115 10036 CHAF1A
CAF-1
CAF1
CAF1B
CAF1P150
P150
chromatin assembly factor 1, subunit A (p150) Arecoline results in decreased expression of CHAF1A mRNA decreases expression
mRNA 17682004
D001115 8208 CHAF1B
CAF-1
CAF-IP60
CAF1
CAF1A
CAF1P60
MPHOSPH7
MPP7
chromatin assembly factor 1, subunit B (p60) Arecoline results in decreased expression of CHAF1B mRNA decreases expression
mRNA 17682004
D001115 1131 CHRM3
EGBRS
HM3
cholinergic receptor, muscarinic 3 brucine promotes the reaction [Arecoline binds to CHRM3 protein] affects binding
/ increases reaction
protein 9224827
D001115 1131 CHRM3
EGBRS
HM3
cholinergic receptor, muscarinic 3 CHRM3 protein binds to Arecoline affects binding
protein 9224827
D001115 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) Arecoline inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein] decreases reaction
/ increases activity
protein 17234337
D001115 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) Arecoline inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] decreases reaction
/ increases expression
mRNA 17234337
D001115 56603 CYP26B1
CYP26A2
P450RAI-2
P450RAI2
RHFCA
cytochrome P450, family 26, subfamily B, polypeptide 1 Arecoline results in decreased expression of CYP26B1 mRNA decreases expression
mRNA 17682004
D001115 64858 DCLRE1B
APOLLO
SNM1B
SNMIB
DNA cross-link repair 1B Arecoline results in decreased expression of DCLRE1B mRNA decreases expression
mRNA 17682004
D001115 54541 DDIT4
Dig2
REDD-1
REDD1
DNA-damage-inducible transcript 4 Arecoline results in increased expression of DDIT4 mRNA increases expression
mRNA 17682004
D001115 3301 DNAJA1
DJ-2
DjA1
HDJ2
HSDJ
HSJ2
HSPF4
NEDD7
hDJ-2
DnaJ (Hsp40) homolog, subfamily A, member 1 Arecoline results in increased expression of DNAJA1 mRNA increases expression
mRNA 17682004
D001115 9521 EEF1E1
AIMP3
P18
eukaryotic translation elongation factor 1 epsilon 1 Arecoline results in decreased expression of EEF1E1 mRNA decreases expression
mRNA 17682004
D001115 2068 ERCC2
COFS2
EM9
TTD
XPD
excision repair cross-complementing rodent repair deficiency, complementation group 2 (EC:3.6.4.12) Arecoline results in decreased expression of ERCC2 mRNA decreases expression
mRNA 17682004
D001115 2189 FANCG
FAG
XRCC9
Fanconi anemia, complementation group G Arecoline results in decreased expression of FANCG mRNA decreases expression
mRNA 17682004
D001115 9518 GDF15
GDF-15
MIC-1
MIC1
NAG-1
PDF
PLAB
PTGFB
growth differentiation factor 15 Arecoline results in increased expression of GDF15 mRNA increases expression
mRNA 17682004
D001115 2937 GSS
GSHS
glutathione synthetase (EC:6.3.2.3) Arecoline results in decreased expression of GSS mRNA decreases expression
mRNA 17682004
D001115 2966 GTF2H2
BTF2
BTF2P44
T-BTF2P44
TFIIH
p44
general transcription factor IIH, polypeptide 2, 44kDa Arecoline results in decreased expression of GTF2H2 mRNA decreases expression
mRNA 17682004
D001115 404672 GTF2H5
C6orf175
TFB5
TFIIH
TGF2H5
TTD
TTD-A
TTDA
bA120J8.2
general transcription factor IIH, polypeptide 5 Arecoline results in decreased expression of GTF2H5 mRNA decreases expression
mRNA 17682004
D001115 51182 HSPA14
HSP70-4
HSP70L1
heat shock 70kDa protein 14 Arecoline results in increased expression of HSPA14 mRNA increases expression
mRNA 17682004
D001115 3569 IL6
BSF2
HGF
HSF
IFNB2
IL-6
interleukin 6 (interferon, beta 2) Arecoline results in decreased expression of IL6 mRNA decreases expression
mRNA 22108589
D001115 3569 IL6
BSF2
HGF
HSF
IFNB2
IL-6
interleukin 6 (interferon, beta 2) Arecoline results in decreased secretion of IL6 protein decreases secretion
protein 22108589
D001115 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 Arecoline results in increased secretion of IL8 protein increases secretion
protein 21297082
D001115 51451 LCMT1
LCMT
PPMT1
leucine carboxyl methyltransferase 1 (EC:2.1.1.233) Arecoline results in decreased expression of LCMT1 mRNA decreases expression
mRNA 17682004
D001115 4128 MAOA
MAO-A
monoamine oxidase A (EC:1.4.3.4) Arecoline results in decreased expression of MAOA mRNA decreases expression
mRNA 17682004
D001115 100302175 MIR1207
MIRN1207
hsa-mir-1207
microRNA 1207 Arecoline results in increased expression of MIR1207 increases expression
21750350
D001115 100188847 MIR1225
MIRN1225
microRNA 1225 Arecoline results in increased expression of MIR1225 increases expression
21750350
D001115 100302142 MIR1246
MIRN1246
hsa-mir-1246
microRNA 1246 Arecoline results in increased expression of MIR1246 increases expression
21750350
D001115 100302233 MIR1268A
MIR1268
MIRN1268
hsa-mir-1268
hsa-mir-1268a
microRNA 1268a Arecoline results in increased expression of MIR1268A increases expression
21750350
D001115 100302276 MIR1290
MIRN1290
hsa-mir-1290
microRNA 1290 Arecoline results in increased expression of MIR1290 increases expression
21750350
D001115 100302270 MIR1305
MIRN1305
hsa-mir-1305
microRNA 1305 Arecoline results in decreased expression of MIR1305 decreases expression
21750350
D001115 406927 MIR136
MIRN136
miRNA136
microRNA 136 Arecoline results in increased expression of MIR136 increases expression
21750350
D001115 406935 MIR143
MIRN143
microRNA 143 Arecoline results in increased expression of MIR143 increases expression
21750350
D001115 406937 MIR145
MIRN145
miR-145
miRNA145
microRNA 145 Arecoline results in increased expression of MIR145 increases expression
21750350
D001115 100302137 MIR1914
MIRN1914
hsa-mir-1914
microRNA 1914 Arecoline results in decreased expression of MIR1914 decreases expression
21750350
D001115 100302129 MIR1915
MIRN1915
hsa-mir-1915
microRNA 1915 Arecoline results in increased expression of MIR1915 increases expression
21750350
D001115 406978 MIR199B
MIRN199B
mir-199b
microRNA 199b Arecoline results in increased expression of MIR199B increases expression
21750350
D001115 407010 MIR23A
MIRN23A
hsa-mir-23a
miRNA23A
microRNA 23a Arecoline results in increased expression of MIR23A increases expression
21750350
D001115 407015 MIR26A1
MIR26A
MIRN26A1
microRNA 26a-1 Arecoline results in increased expression of MIR26A1 increases expression
21750350
D001115 407017 MIR26B
MIRN26B
hsa-mir-26b
miR-26b
microRNA 26b Arecoline results in increased expression of MIR26B increases expression
21750350
D001115 407026 MIR29C
MIRN29C
miRNA29C
microRNA 29c Arecoline results in increased expression of MIR29C increases expression
21750350
D001115 407029 MIR30A
MIRN30A
microRNA 30a Arecoline results in increased expression of MIR30A increases expression
21750350
D001115 693215 MIR630
MIRN630
hsa-mir-630
microRNA 630 Arecoline results in increased expression of MIR630 increases expression
21750350
D001115 4292 MLH1
COCA2
FCC2
HNPCC
HNPCC2
hMLH1
mutL homolog 1 Arecoline results in decreased expression of MLH1 mRNA decreases expression
mRNA 17682004
D001115 4313 MMP2
CLG4
CLG4A
MMP-II
MONA
TBE-1
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) Arecoline results in decreased secretion of MMP2 protein decreases secretion
protein 16311067
D001115 4436 MSH2
COCA1
FCC1
HNPCC
HNPCC1
LCFS2
mutS homolog 2 Arecoline results in decreased expression of MSH2 mRNA decreases expression
mRNA 17682004
D001115 4489 MT1A
MT1
MT1S
MTC
metallothionein 1A Arecoline results in increased expression of MT1A mRNA increases expression
mRNA 17418620
D001115 4489 MT1A
MT1
MT1S
MTC
metallothionein 1A Benzo(a)pyrene promotes the reaction [Arecoline results in increased expression of MT1A mRNA] increases expression
/ increases reaction
mRNA 17418620
D001115 9027 NAT8
ATase2
CML1
GLA
Hcml1
TSC501
TSC510
N-acetyltransferase 8 (GCN5-related, putative) Arecoline results in decreased expression of NAT8 mRNA decreases expression
mRNA 17682004
D001115 5591 PRKDC
DNA-PKcs
DNAPK
DNPK1
HYRC
HYRC1
XRCC7
p350
protein kinase, DNA-activated, catalytic polypeptide (EC:2.7.11.1) Arecoline results in decreased expression of PRKDC mRNA decreases expression
mRNA 17682004
D001115 5743 PTGS2
COX-2
COX2
GRIPGHS
PGG/HS
PGHS-2
PHS-2
hCox-2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) Arecoline results in increased expression of PTGS2 increases expression
16311067
D001115 5743 PTGS2
COX-2
COX2
GRIPGHS
PGG/HS
PGHS-2
PHS-2
hCox-2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) Arecoline results in increased expression of PTGS2 mRNA increases expression
mRNA 17682004
D001115 5810 RAD1
HRAD1
REC1
RAD1 homolog (S. pombe) (EC:3.1.11.2) Arecoline results in decreased expression of RAD1 mRNA decreases expression
mRNA 17682004
D001115 10111 RAD50
NBSLD
RAD502
hRad50
RAD50 homolog (S. cerevisiae) Arecoline results in increased expression of RAD50 mRNA increases expression
mRNA 17682004
D001115 6283 S100A12
CAAF1
CAGC
CGRP
ENRAGE
MRP-6
MRP6
p6
S100 calcium binding protein A12 Arecoline results in decreased expression of S100A12 mRNA decreases expression
mRNA 17682004
D001115 8243 SMC1A
CDLS2
DXS423E
SB1.8
SMC1
SMC1L1
SMC1alpha
SMCB
structural maintenance of chromosomes 1A Arecoline results in decreased expression of SMC1A mRNA decreases expression
mRNA 17682004
D001115 7076 TIMP1
CLGI
EPA
EPO
HCI
TIMP
TIMP metallopeptidase inhibitor 1 Arecoline results in increased expression of TIMP1 mRNA increases expression
mRNA 16311067
D001115 7076 TIMP1
CLGI
EPA
EPO
HCI
TIMP
TIMP metallopeptidase inhibitor 1 Arecoline results in increased expression of TIMP1 protein increases expression
protein 16311067
D001115 7157 TP53
BCC7
LFS1
P53
TRP53
tumor protein p53 [[Arecoline results in decreased expression of CDC25C] co-treated with [Arecoline results in increased expression of TP53]] results in decreased activity of CDK1 protein affects cotreatment
/ decreases activity
/ decreases expression
/ increases expression
22108589
D001115 7157 TP53
BCC7
LFS1
P53
TRP53
tumor protein p53 Arecoline results in increased expression of TP53 protein increases expression
protein 22108589
D001115 56886 UGGT1
HUGT1
UGCGL1
UGT1
UDP-glucose glycoprotein glucosyltransferase 1 Arecoline results in decreased expression of UGGT1 mRNA decreases expression
mRNA 17682004
D001115 100126299 VTRNA2-1
CBL-3
CBL3
MIR886
MIRN886
VTRNA2
hsa-mir-886
hvg-5
nc886
vault RNA 2-1 Arecoline results in decreased expression of VTRNA2-1 decreases expression
21750350

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (22)

OMIM preferred title UniProt
#100100 Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism P20309
#103780 Alcohol dependence P08172
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#608516 Major depressive disorder; mdd P08172
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#275210 Restrictive dermopathy, lethal P02545
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828

KEGG DISEASE (18)

KEGG disease name UniProt
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00036 Osteosarcoma P08684 (marker)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)

Diseases related to CTD interactions

21 disease from interactions of metabolites

MeSH disease OMIM compound disease name evidence type reference
pmid
D000647 D001115 Amnesia therapeutic
2724699
3137602
3227033
3244205
D001919 D001115 Bradycardia marker/mechanism
4094621
D002277 D001115 Carcinoma marker/mechanism
19840781
D002280 D001115 Carcinoma, Basal Cell therapeutic
22108589
D002375 D001115 Catalepsy marker/mechanism
therapeutic
403561
989390
6268258
D020820 D001115 Dyskinesias marker/mechanism
6320248
D006965 D001115 Hyperplasia marker/mechanism
19840781
D007022 D001115 Hypotension therapeutic
8010419
D007153 D001115 Immunologic Deficiency Syndromes marker/mechanism
6857660
D009062 D001115 Mouth Neoplasms marker/mechanism
17682004
D009127 D001115 Muscle Rigidity marker/mechanism
569589
D009374 D001115 Neoplasms, Experimental marker/mechanism
19840781
D019954 D001115 Neurobehavioral Manifestations therapeutic
11370760
D009914 D001115 Oral Submucous Fibrosis marker/mechanism
16311067
D010212 D001115 Papilloma marker/mechanism
19840781
D010243 D001115 Paralysis marker/mechanism
6130710
6258692
D020734 D001115 Parkinsonian Disorders marker/mechanism
569589
D011470 D001115 Prostatic Hyperplasia marker/mechanism
21741983
D013226 D001115 Status Epilepticus marker/mechanism
2824229
D014062 D001115 Tongue Neoplasms marker/mechanism
19840781
D014202 D001115 Tremor marker/mechanism
569589
1458168
1664807
3378602
4048228
6258692
7246199
8205054
8937624
9231353
9877318
18767395