KNApSAcK Entry

Organism name Areca catechu
Genus Areca
Family Palmae
Kingdom Plantae

NCBI taxonomy


Linked NCBI taxonomy name Areca catechu
Linked NCBI taxonomy ID 184783
Linked level species


Family in NCBI taxonomy Arecaceae
ID 4710

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Liliopsida
ID 4447

Natural Activity

List (38)

Species Activity
Areca catechu L. Abortifacient
Areca catechu L. Antibacterial
Areca catechu L. Antidote, abrin
Areca catechu L. Antiimplantation
Areca catechu L. Antiinfertility
Areca catechu L. Antioxidant
Areca catechu L. Antiradicular
Areca catechu L. Antiseptic
Areca catechu L. Astringent
Areca catechu L. Bradycardic
Areca catechu L. Bronchostimulant
Areca catechu L. Candidistat
Areca catechu L. Carcinogenic
Areca catechu L. Cardiac
Areca catechu L. Cholinergic
Areca catechu L. CNS-Depressant
Areca catechu L. CNS-Stimulant
Areca catechu L. Dentifrice
Areca catechu L. Deobstruent
Areca catechu L. Diaphoretic
Areca catechu L. Digestive
Areca catechu L. Emmenagogue
Areca catechu L. Euphoriant
Areca catechu L. Gastrostimulant
Areca catechu L. Mitotic
Areca catechu L. Muscarinic
Areca catechu L. Mydriatic
Areca catechu L. Narcotic
Areca catechu L. Oxytocic
Areca catechu L. Parasympathetic
Areca catechu L. Sedative
Areca catechu L. Sialagogue
Areca catechu L. Spasmogenic
Areca catechu L. Stimulant
Areca catechu L. Stomachic
Areca catechu L. Tremorigenic
Areca catechu L. Vasoconstrictor
Areca catechu L. Vermifuge

Metabolite list (17)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
C00009277 External link 512 Proanthocyanidin A1
13 / 3 / 4 No. 16 No. 19
C00009074 External link 512 Procyanidin B7
/ Catechin-(4beta->6)-catechin
No. 16 No. 19
C00009089 External link 512 Arecatannin B1
2 / 3 / 4 No. 29 No. 19
C00009097 External link 512 Arecatamnin A1
/ [Epicatechin-(4beta->8)]2-catechin
13 / 5 / 6 No. 29 No. 19
C00009086 External link 512 Epicatechin-(4beta->6)-epicatechin-(4beta->8)-catechin
2 / 3 / 4 No. 29 No. 19
C00009095 External link 512 Procyanidin C4
13 / 5 / 6 No. 29 No. 19
C00009105 External link 512 [Epicatechin-(4beta->8)]2-epicatechin-(4beta->6)-catechin
No. 113 No. 19
C00009106 External link 512 Arecatannin A2
No. 113 No. 19
C00002057 External link 512 Nicotine
131 / 72 / 55 370 / 191 No. 2084 No. 1
C00044165 External link 512 Ethyl N-methyl-1,2,5,6-tetrahydro-pyridine-3-carboxylate
No. 3405 No. 1
C00002020 External link 512 Arecoline
15 / 22 / 18 64 / 21 No. 3405 No. 1
C00044191 External link 512 Guvacoline
1 / 1 / 0 No. 3405 No. 1
C00002019 External link 512 Arecaidine
1 / 0 No. 5088 No. 1
C00002043 External link 512 Guvacine
13 / 5 / 5 No. 5088 No. 1
C00044164 External link 512 Ethyl nicotinate
No. 5102
C00044235 External link 512 Methyl nicotinate
6 / 3 / 7 No. 5102
C00044166 External link 512 Ethyl N-methylpiperidine-3-carboxylate
No. 8929

Human Protein / Gene in interactions

151 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
P14780 Matrix metalloproteinase-9 M10A C00002057 C00009086 C00009089 C00009095 C00009097 2 / 2
P17252 Protein kinase C alpha type Alpha C00002057 C00009095 C00009097 C00009277 0 / 0
P08253 72 kDa type IV collagenase M10A C00009086 C00009089 C00009095 C00009097 1 / 3
Q02156 Protein kinase C epsilon type Eta C00009095 C00009097 C00009277 0 / 0
P05771 Protein kinase C beta type Alpha C00009095 C00009097 C00009277 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00002020 C00002043 C00002057 0 / 1
P20309 Muscarinic acetylcholine receptor M3 Acetylcholine receptor C00002020 C00002057 C00044191 1 / 0
P05129 Protein kinase C gamma type Alpha C00009095 C00009097 C00009277 1 / 1
Q05655 Protein kinase C delta type Delta C00009095 C00009097 C00009277 0 / 0
O94806 Serine/threonine-protein kinase D3 Pkd C00009095 C00009097 C00009277 0 / 0
P24723 Protein kinase C eta type Eta C00009095 C00009097 C00009277 1 / 0
Q04759 Protein kinase C theta type Delta C00009095 C00009097 C00009277 0 / 1
Q05513 Protein kinase C zeta type Iota C00009095 C00009097 C00009277 0 / 0
Q01196 Runt-related transcription factor 1 Unclassified protein C00002020 C00002057 C00044235 1 / 4
Q13951 Core-binding factor subunit beta Unclassified protein C00002020 C00002057 C00044235 0 / 1
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00002020 C00002043 C00002057 1 / 0
P41743 Protein kinase C iota type Iota C00009095 C00009097 C00009277 0 / 0
Q15139 Serine/threonine-protein kinase D1 Pkd C00009095 C00009097 C00009277 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002020 C00002043 C00002057 0 / 1
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00002020 C00002043 C00002057 1 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00002020 C00002043 C00002057 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00002043 C00002057 C00044235 0 / 0
P08173 Muscarinic acetylcholine receptor M4 Acetylcholine receptor C00002020 C00002057 0 / 0
P02545 Prelamin-A/C Unclassified protein C00002020 C00002057 11 / 10
P21728 D(1A) dopamine receptor Dopamine receptor C00002043 C00002057 0 / 0
P11229 Muscarinic acetylcholine receptor M1 Acetylcholine receptor C00002020 C00002057 0 / 0
P08172 Muscarinic acetylcholine receptor M2 Acetylcholine receptor C00002020 C00002057 2 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00002043 C00002057 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00002057 C00044235 0 / 0
P08912 Muscarinic acetylcholine receptor M5 Acetylcholine receptor C00002020 C00002057 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00002057 C00044235 0 / 0
P49798 Regulator of G-protein signaling 4 Unclassified protein C00002020 C00002057 2 / 0
P25103 Substance-P receptor Neurokinin receptor C00002057 0 / 0
P25024 C-X-C chemokine receptor type 1 CXC chemokine receptor C00002057 0 / 0
P06241 Tyrosine-protein kinase Fyn Src C00002057 0 / 0
Q08209 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform Ser_Thr C00002057 0 / 0
P13945 Beta-3 adrenergic receptor Adrenergic receptor C00002057 0 / 0
P30926 Neuronal acetylcholine receptor subunit beta-4 CHRN beta C00002057 0 / 0
Q07001 Acetylcholine receptor subunit delta CHRN delta C00002057 3 / 2
P43681 Neuronal acetylcholine receptor subunit alpha-4 CHRN alpha C00002057 1 / 1
P07510 Acetylcholine receptor subunit gamma CHRN gamma C00002057 2 / 1
P17787 Neuronal acetylcholine receptor subunit beta-2 CHRN beta C00002057 1 / 1
P02708 Acetylcholine receptor subunit alpha CHRN alpha C00002057 3 / 2
P11230 Acetylcholine receptor subunit beta CHRN beta C00002057 2 / 1
P49763 Placenta growth factor Unclassified protein C00009277 0 / 0
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily C00002057 1 / 8
P11473 Vitamin D3 receptor NR1I1 C00044235 2 / 3
P14416 D(2) dopamine receptor Dopamine receptor C00002057 2 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00002057 0 / 0
P37288 Vasopressin V1a receptor Vasopressin and oxytocin receptor C00002057 0 / 0
P41145 Kappa-type opioid receptor Opioid receptor C00002057 0 / 0
Q9Y271 Cysteinyl leukotriene receptor 1 Leukotriene receptor C00002057 0 / 0
P29274 Adenosine receptor A2a Adenosine receptor C00002057 0 / 0
P25929 Neuropeptide Y receptor type 1 Neuropeptide Y receptor C00002057 0 / 0
P50052 Type-2 angiotensin II receptor Angiotensin receptor C00002057 1 / 1
P17948 Vascular endothelial growth factor receptor 1 Vegfr C00002057 0 / 0
P41968 Melanocortin receptor 3 Melanocortin receptor C00002057 1 / 0
P18825 Alpha-2C adrenergic receptor Adrenergic receptor C00002057 0 / 0
P48065 Sodium- and chloride-dependent betaine transporter Betaine and GABA Na-symporter C00002043 0 / 0
P11509 Cytochrome P450 2A6 Cytochrome P450 2A6 C00002057 0 / 0
Q01959 Sodium-dependent dopamine transporter Dopamine C00002057 1 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00002057 2 / 0
O75496 Geminin Unclassified protein C00002057 0 / 0
P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase Oxidoreductase C00002057 0 / 0
P08913 Alpha-2A adrenergic receptor Adrenergic receptor C00002057 0 / 0
P21917 D(4) dopamine receptor Dopamine receptor C00002057 0 / 0
P30988 Calcitonin receptor Calcitonin receptor C00002057 0 / 0
P35462 D(3) dopamine receptor Dopamine receptor C00002057 1 / 0
P41143 Delta-type opioid receptor Opioid receptor C00002057 0 / 0
P46098 5-hydroxytryptamine receptor 3A NS C00002057 0 / 0
Q92731 Estrogen receptor beta NR3A2 C00002057 0 / 1
P41595 5-hydroxytryptamine receptor 2B Serotonin receptor C00002057 0 / 0
P25101 Endothelin-1 receptor Endothelin receptor C00002057 0 / 0
P30411 B2 bradykinin receptor Bradykinin receptor C00002057 0 / 0
P10145 Interleukin-8 Secreted protein C00002057 0 / 0
P32245 Melanocortin receptor 4 Melanocortin receptor C00002057 1 / 0
P32238 Cholecystokinin receptor type A Cholecystokinin receptor C00002057 0 / 0
P08311 Cathepsin G S1A C00002057 0 / 0
Q99720 Sigma non-opioid intracellular receptor 1 Membrane receptor C00002057 1 / 0
P03956 Interstitial collagenase M10A C00002057 0 / 1
P32241 Vasoactive intestinal polypeptide receptor 1 Vasoactive intestinal peptide receptor C00002057 0 / 0
P35367 Histamine H1 receptor Histamine receptor C00002057 0 / 0
Q9NPD5 Solute carrier organic anion transporter family member 1B3 Electrochemical transporter C00002057 1 / 0
P04150 Glucocorticoid receptor NR3C1 C00002057 0 / 1
P25021 Histamine H2 receptor Histamine receptor C00002057 0 / 0
P21397 Amine oxidase [flavin-containing] A Oxidoreductase C00002057 1 / 1
P21554 Cannabinoid receptor 1 Cannabinoid receptor C00002057 0 / 0
P31645 Sodium-dependent serotonin transporter Serotonin C00002057 2 / 0
P15692 Vascular endothelial growth factor A Secreted protein C00009277 1 / 2
P04626 Receptor tyrosine-protein kinase erbB-2 TK tyrosine-protein kinase EGFR subfamily C00002057 5 / 9
P07550 Beta-2 adrenergic receptor Adrenergic receptor C00002057 0 / 1
P21452 Substance-K receptor Neurokinin receptor C00002057 0 / 0
P51679 C-C chemokine receptor type 4 CC chemokine receptor C00002057 0 / 0
P51681 C-C chemokine receptor type 5 CC chemokine receptor C00002057 3 / 0
P50406 5-hydroxytryptamine receptor 6 Serotonin receptor C00002057 0 / 0
P36544 Neuronal acetylcholine receptor subunit alpha-7 CHRN alpha C00002057 0 / 0
P41597 C-C chemokine receptor type 2 CC chemokine receptor C00002057 1 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00002057 0 / 0
P08575 Receptor-type tyrosine-protein phosphatase C Enzyme C00002057 2 / 1
P00918 Carbonic anhydrase 2 Lyase C00002057 1 / 2
P10828 Thyroid hormone receptor beta NR1A2 C00002020 3 / 1
Q92887 Canalicular multispecific organic anion transporter 1 Unclassified protein C00002057 1 / 1
O75762 Transient receptor potential cation channel subfamily A member 1 Unclassified protein C00002057 1 / 0
P51449 Nuclear receptor ROR-gamma Nuclear hormone receptor subfamily 1 group F member 3 C00002057 0 / 0
O76074 cGMP-specific 3',5'-cyclic phosphodiesterase PDE_5A C00002057 0 / 0
P03372 Estrogen receptor NR3A1 C00002057 1 / 1
P08588 Beta-1 adrenergic receptor Adrenergic receptor C00002057 1 / 0
P22303 Acetylcholinesterase Hydrolase C00002057 1 / 0
P28223 5-hydroxytryptamine receptor 2A Serotonin receptor C00002057 0 / 0
P28335 5-hydroxytryptamine receptor 2C Serotonin receptor C00002057 0 / 0
P35372 Mu-type opioid receptor Opioid receptor C00002057 0 / 0
P16473 Thyrotropin receptor Glycohormone receptor C00002043 3 / 2
P32297 Neuronal acetylcholine receptor subunit alpha-3 CHRN alpha C00002057 1 / 0
P25105 Platelet-activating factor receptor PAF receptor C00002057 0 / 0
P33032 Melanocortin receptor 5 Melanocortin receptor C00002057 0 / 0
O15245 Solute carrier family 22 member 1 Drug uniporter C00002057 0 / 0
Q9NSD5 Sodium- and chloride-dependent GABA transporter 2 GABA C00002043 0 / 0
P05181 Cytochrome P450 2E1 Cytochrome P450 2E1 C00002057 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00002057 4 / 3
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00002057 0 / 0
P23975 Sodium-dependent noradrenaline transporter Norepinephrine C00002057 1 / 1
P25100 Alpha-1D adrenergic receptor Adrenergic receptor C00002057 0 / 0
P30542 Adenosine receptor A1 Adenosine receptor C00002057 0 / 0
P18089 Alpha-2B adrenergic receptor Adrenergic receptor C00002057 0 / 0
P24557 Thromboxane-A synthase Cytochrome P450 5A1 C00002057 1 / 1
P06239 Tyrosine-protein kinase Lck Src C00002057 0 / 1
P25025 C-X-C chemokine receptor type 2 CXC chemokine receptor C00002057 0 / 0
P27361 Mitogen-activated protein kinase 3 Erk C00002057 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00002057 1 / 1
P29466 Caspase-1 C14 C00002057 0 / 0
P49146 Neuropeptide Y receptor type 2 Neuropeptide Y receptor C00002057 0 / 0
Q16539 Mitogen-activated protein kinase 14 p38 C00002057 0 / 0
P33765 Adenosine receptor A3 Adenosine receptor C00002057 0 / 0
P08246 Neutrophil elastase S1A C00002057 2 / 1
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) C00002057 2 / 2
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00002057 0 / 3
P30531 Sodium- and chloride-dependent GABA transporter 1 GABA C00002043 0 / 0
O94956 Solute carrier organic anion transporter family member 2B1 Unclassified protein C00002057 0 / 0
O15244 Solute carrier family 22 member 2 Drug uniporter C00002057 0 / 0
Q9Y6L6 Solute carrier organic anion transporter family member 1B1 Electrochemical transporter C00002057 1 / 0
P48066 Sodium- and chloride-dependent GABA transporter 3 GABA C00002043 0 / 0
Q15822 Neuronal acetylcholine receptor subunit alpha-2 CHRN alpha C00002057 1 / 1
Q9H015 Solute carrier family 22 member 4 Unclassified protein C00002057 1 / 1
O76082 Solute carrier family 22 member 5 Unclassified protein C00002057 1 / 2
Q8WXA8 5-hydroxytryptamine receptor 3C NS C00002057 0 / 0
Q70Z44 5-hydroxytryptamine receptor 3D NS C00002057 0 / 0
O95264 5-hydroxytryptamine receptor 3B NS C00002057 0 / 0
A5X5Y0 5-hydroxytryptamine receptor 3E NS C00002057 0 / 0
Q05901 Neuronal acetylcholine receptor subunit beta-3 CHRN beta C00002057 0 / 0
P30532 Neuronal acetylcholine receptor subunit alpha-5 CHRN alpha C00002057 1 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein C00002057 1 / 1

422 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
7076 TIMP1, CLGI, EPA, EPO, HCI, TIMP TIMP metallopeptidase inhibitor 1 C00002019 C00002020 C00002057
672 BRCA1, BRCAI, BRCC1, BROVCA1, IRIS, PNCA4, PPP1R53, PSCP, RNF53 breast cancer 1, early onset C00002020 C00002057
10111 RAD50, NBSLD, RAD502, hRad50 RAD50 homolog (S. cerevisiae) C00002020 C00002057
5743 PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC: C00002020 C00002057
4313 MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC: C00002020 C00002057
596 BCL2, Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 C00002020 C00002057
7157 TP53, BCC7, LFS1, P53, TRP53 tumor protein p53 C00002020 C00002057
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC: C00002020 C00002057
6352 CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP chemokine (C-C motif) ligand 5 C00002020 C00002057
3576 IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 interleukin 8 C00002020 C00002057
3569 IL6, BSF2, HGF, HSF, IFNB2, IL-6 interleukin 6 (interferon, beta 2) C00002020 C00002057
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC: C00002020 C00002057
6814 STXBP3, MUNC18-3, MUNC18C, PSP, UNC-18C syntaxin binding protein 3 C00002057
8208 CHAF1B, CAF-1, CAF-IP60, CAF1, CAF1A, CAF1P60, MPHOSPH7, MPP7 chromatin assembly factor 1, subunit B (p60) C00002020
1131 CHRM3, EGBRS, HM3 cholinergic receptor, muscarinic 3 C00002020
983 CDK1, CDC2, CDC28A, P34CDC2 cyclin-dependent kinase 1 (EC: C00002020
56603 CYP26B1, CYP26A2, P450RAI-2, P450RAI2, RHFCA cytochrome P450, family 26, subfamily B, polypeptide 1 C00002020
64858 DCLRE1B, APOLLO, SNM1B, SNMIB DNA cross-link repair 1B C00002020
54541 DDIT4, Dig2, REDD-1, REDD1 DNA-damage-inducible transcript 4 C00002020
3301 DNAJA1, DJ-2, DjA1, HDJ2, HSDJ, HSJ2, HSPF4, NEDD7, hDJ-2 DnaJ (Hsp40) homolog, subfamily A, member 1 C00002020
9521 EEF1E1, AIMP3, P18 eukaryotic translation elongation factor 1 epsilon 1 C00002020
2068 ERCC2, COFS2, EM9, TTD, XPD excision repair cross-complementing rodent repair deficiency, complementation group 2 (EC: C00002020
2189 FANCG, FAG, XRCC9 Fanconi anemia, complementation group G C00002020
9518 GDF15, GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB growth differentiation factor 15 C00002020
2937 GSS, GSHS glutathione synthetase (EC: C00002020
2966 GTF2H2, BTF2, BTF2P44, T-BTF2P44, TFIIH, p44 general transcription factor IIH, polypeptide 2, 44kDa C00002020
404672 GTF2H5, C6orf175, TFB5, TFIIH, TGF2H5, TTD, TTD-A, TTDA, bA120J8.2 general transcription factor IIH, polypeptide 5 C00002020
51182 HSPA14, HSP70-4, HSP70L1 heat shock 70kDa protein 14 C00002020
995 CDC25C, CDC25, PPP1R60 cell division cycle 25C (EC: C00002020
902 CCNH, CAK, p34, p37 cyclin H C00002020
51451 LCMT1, LCMT, PPMT1 leucine carboxyl methyltransferase 1 (EC: C00002020
4128 MAOA, MAO-A monoamine oxidase A (EC: C00002020
100302175 MIR1207, MIRN1207, hsa-mir-1207 microRNA 1207 C00002020
100188847 MIR1225, MIRN1225 microRNA 1225 C00002020
100302142 MIR1246, MIRN1246, hsa-mir-1246 microRNA 1246 C00002020
100302233 MIR1268A, MIR1268, MIRN1268, hsa-mir-1268, hsa-mir-1268a microRNA 1268a C00002020
100302276 MIR1290, MIRN1290, hsa-mir-1290 microRNA 1290 C00002020
100302270 MIR1305, MIRN1305, hsa-mir-1305 microRNA 1305 C00002020
406927 MIR136, MIRN136, miRNA136 microRNA 136 C00002020
406935 MIR143, MIRN143 microRNA 143 C00002020
406937 MIR145, MIRN145, miR-145, miRNA145 microRNA 145 C00002020
100302137 MIR1914, MIRN1914, hsa-mir-1914 microRNA 1914 C00002020
100302129 MIR1915, MIRN1915, hsa-mir-1915 microRNA 1915 C00002020
406978 MIR199B, MIRN199B, mir-199b microRNA 199b C00002020
407010 MIR23A, MIRN23A, hsa-mir-23a, miRNA23A microRNA 23a C00002020
407015 MIR26A1, MIR26A, MIRN26A1 microRNA 26a-1 C00002020
407017 MIR26B, MIRN26B, hsa-mir-26b, miR-26b microRNA 26b C00002020
407026 MIR29C, MIRN29C, miRNA29C microRNA 29c C00002020
407029 MIR30A, MIRN30A microRNA 30a C00002020
693215 MIR630, MIRN630, hsa-mir-630 microRNA 630 C00002020
4292 MLH1, COCA2, FCC2, HNPCC, HNPCC2, hMLH1 mutL homolog 1 C00002020
328 APEX1, APE, APE1, APEN, APEX, APX, HAP1, REF1 APEX nuclease (multifunctional DNA repair enzyme) 1 (EC: C00002020
4436 MSH2, COCA1, FCC1, HNPCC, HNPCC1, LCFS2 mutS homolog 2 C00002020
4489 MT1A, MT1, MT1S, MTC metallothionein 1A C00002020
9027 NAT8, ATase2, CML1, GLA, Hcml1, TSC501, TSC510 N-acetyltransferase 8 (GCN5-related, putative) C00002020
5591 PRKDC, DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350 protein kinase, DNA-activated, catalytic polypeptide (EC: C00002020
223 ALDH9A1, ALDH4, ALDH7, ALDH9, E3, TMABADH aldehyde dehydrogenase 9 family, member A1 (EC: C00002020
5810 RAD1, HRAD1, REC1 RAD1 homolog (S. pombe) (EC: C00002020
10327 AKR1A1, ALDR1, ALR, ARM, DD3 aldo-keto reductase family 1, member A1 (aldehyde reductase) (EC: C00002020
6283 S100A12, CAAF1, CAGC, CGRP, ENRAGE, MRP-6, MRP6, p6 S100 calcium binding protein A12 C00002020
8243 SMC1A, CDLS2, DXS423E, SB1.8, SMC1, SMC1L1, SMC1alpha, SMCB structural maintenance of chromosomes 1A C00002020
57491 AHRR, AHH, AHHR, bHLHe77 aryl-hydrocarbon receptor repressor C00002020
56886 UGGT1, HUGT1, UGCGL1, UGT1 UDP-glucose glycoprotein glucosyltransferase 1 C00002020
100126299 VTRNA2-1, CBL-3, CBL3, MIR886, MIRN886, VTRNA2, hsa-mir-886, hvg-5, nc886 vault RNA 2-1 C00002020
9625 AATK, AATYK, AATYK1, LMR1, LMTK1, p35BP apoptosis-associated tyrosine kinase (EC: C00002057
1636 ACE, ACE1, CD143, DCP, DCP1, ICH, MVCD3 angiotensin I converting enzyme (EC: C00002057
153 ADRB1, ADRB1R, B1AR, BETA1AR, RHR adrenoceptor beta 1 C00002057
154 ADRB2, ADRB2R, ADRBR, B2AR, BAR, BETA2AR adrenoceptor beta 2, surface C00002057
207 AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA v-akt murine thymoma viral oncogene homolog 1 (EC: C00002057
210 ALAD, ALADH, PBGS aminolevulinate dehydratase (EC: C00002057
216 ALDH1A1, ALDC, ALDH-E1, ALDH1, ALDH11, PUMB1, RALDH1 aldehyde dehydrogenase 1 family, member A1 (EC: C00002057
240 ALOX5, 5-LO, 5-LOX, 5LPG, LOG5 arachidonate 5-lipoxygenase (EC: C00002057
262 AMD1, ADOMETDC, AMD, SAMDC adenosylmethionine decarboxylase 1 (EC: C00002057
269 AMHR2, AMHR, MISR2, MISRII, MRII anti-Mullerian hormone receptor, type II (EC: C00002057
327 APEH, AARE, ACPH, APH, D3F15S2, D3S48E, DNF15S2, OPH acylaminoacyl-peptide hydrolase (EC: C00002057
351 APP, AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2 amyloid beta (A4) precursor protein C00002057
55082 ARGLU1 arginine and glutamate rich 1 C00002057
8874 ARHGEF7, BETA-PIX, COOL-1, COOL1, Nbla10314, P50, P50BP, P85, P85COOL1, P85SPR, PAK3, PIXB Rho guanine nucleotide exchange factor (GEF) 7 C00002057
408 ARRB1, ARB1, ARR1 arrestin, beta 1 C00002057
546 ATRX, ATR2, JMS, MRXHF1, RAD54, RAD54L, SFM1, SHS, XH2, XNP, ZNF-HX alpha thalassemia/mental retardation syndrome X-linked (EC: C00002057
572 BAD, BBC2, BCL2L8 BCL2-associated agonist of cell death C00002057
581 BAX, BCL2L4 BCL2-associated X protein C00002057
597 BCL2A1, ACC-1, ACC-2, BCL2L5, BFL1, GRS, HBPA1 BCL2-related protein A1 C00002057
627 BDNF, ANON2, BULN2 brain-derived neurotrophic factor C00002057
632 BGLAP, BGP, OC, OCN bone gamma-carboxyglutamate (gla) protein C00002057
329 BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1 baculoviral IAP repeat containing 2 C00002057
332 BIRC5, API4, EPR-1 baculoviral IAP repeat containing 5 C00002057
648 BMI1, FLVI2/BMI1, PCGF4, RNF51 BMI1 polycomb ring finger oncogene C00002057
689 BTF3, BETA-NAC, BTF3a, BTF3b, NACB basic transcription factor 3 C00002057
695 BTK, AGMX1, AT, ATK, BPK, IMD1, PSCTK1, XLA Bruton agammaglobulinemia tyrosine kinase (EC: C00002057
728 C5AR1, C5A, C5AR, C5R1, CD88 complement component 5a receptor 1 C00002057
730 C7 complement component 7 C00002057
811 CALR, CRT, RO, SSA, cC1qR calreticulin C00002057
830 CAPZA2, CAPPA2, CAPZ capping protein (actin filament) muscle Z-line, alpha 2 C00002057
9607 CARTPT, CART CART prepropeptide C00002057
834 CASP1, ICE, IL1BC, P45 caspase 1, apoptosis-related cysteine peptidase (EC: C00002057
842 CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 caspase 9, apoptosis-related cysteine peptidase (EC: C00002057
867 CBL, C-CBL, CBL2, FRA11B, NSLL, RNF55 Cbl proto-oncogene, E3 ubiquitin protein ligase C00002057
11335 CBX3, HECH, HP1-GAMMA, HP1Hs-gamma chromobox homolog 3 C00002057
6360 CCL16, CKb12, HCC-4, ILINCK, LCC-1, LEC, LMC, Mtn-1, NCC-4, NCC4, SCYA16, SCYL4 chemokine (C-C motif) ligand 16 C00002057
890 CCNA2, CCN1, CCNA cyclin A2 C00002057
891 CCNB1, CCNB cyclin B1 C00002057
595 CCND1, BCL1, D11S287E, PRAD1, U21B31 cyclin D1 C00002057
894 CCND2, KIAK0002 cyclin D2 C00002057
898 CCNE1, CCNE cyclin E1 C00002057
901 CCNG2 cyclin G2 C00002057
1234 CCR5, CC-CKR-5, CCCKR5, CCR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22 chemokine (C-C motif) receptor 5 (gene/pseudogene) C00002057
1235 CCR6, BN-1, C-C_CKR-6, CC-CKR-6, CCR-6, CD196, CKR-L3, CKRL3, CMKBR6, DCR2, DRY6, GPR29, GPRCY4, STRL22 chemokine (C-C motif) receptor 6 C00002057
9973 CCS copper chaperone for superoxide dismutase C00002057
920 CD4, CD4mut CD4 molecule C00002057
4179 CD46, AHUS2, MCP, MIC10, TLX, TRA2.10 CD46 molecule, complement regulatory protein C00002057
966 CD59, 16.3A5, 1F5, EJ16, EJ30, EL32, G344, HRF-20, HRF20, MAC-IP, MACIF, MEM43, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, p18-20 CD59 molecule, complement regulatory protein C00002057
993 CDC25A, CDC25A2 cell division cycle 25A (EC: C00002057
990 CDC6, CDC18L, HsCDC18, HsCDC6 cell division cycle 6 C00002057
999 CDH1, Arc-1, CD324, CDHE, ECAD, LCAM, UVO cadherin 1, type 1, E-cadherin (epithelial) C00002057
8621 CDK13, CDC2L, CDC2L5, CHED, hCDK13 cyclin-dependent kinase 13 (EC: C00002057
1019 CDK4, CMM3, PSK-J3 cyclin-dependent kinase 4 (EC: C00002057
1021 CDK6, PLSTIRE cyclin-dependent kinase 6 (EC: C00002057
1026 CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 cyclin-dependent kinase inhibitor 1A (p21, Cip1) C00002057
1027 CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1 cyclin-dependent kinase inhibitor 1B (p27, Kip1) C00002057
1051 CEBPB, C/EBP-beta, CRP2, IL6DBP, LAP, LIP, NF-IL6, TCF5 CCAAT/enhancer binding protein (C/EBP), beta C00002057
1062 CENPE, CENP-E, KIF10, PPP1R61 centromere protein E, 312kDa C00002057
1106 CHD2, EEOC chromodomain helicase DNA binding protein 2 (EC: C00002057
1135 CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal) C00002057
1136 CHRNA3, LNCR2, NACHRA3, PAOD2 cholinergic receptor, nicotinic, alpha 3 (neuronal) C00002057
1137 CHRNA4, BFNC, EBN, EBN1, NACHR, NACHRA4, NACRA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) C00002057
1138 CHRNA5, LNCR2 cholinergic receptor, nicotinic, alpha 5 (neuronal) C00002057
8973 CHRNA6, CHNRA6 cholinergic receptor, nicotinic, alpha 6 (neuronal) C00002057
1139 CHRNA7, CHRNA7-2, NACHRA7 cholinergic receptor, nicotinic, alpha 7 (neuronal) C00002057
1141 CHRNB2, EFNL3, nAChRB2 cholinergic receptor, nicotinic, beta 2 (neuronal) C00002057
1143 CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) C00002057
1160 CKMT2, SMTCK creatine kinase, mitochondrial 2 (sarcomeric) (EC: C00002057
100196409 C00002057
1164 CKS2, CKSHS2 CDC28 protein kinase regulatory subunit 2 C00002057
23155 CLCC1, MCLC chloride channel CLIC-like 1 C00002057
1182 CLCN3, CLC3, ClC-3 chloride channel, voltage-sensitive 3 C00002057
1192 CLIC1, G6, NCC27 chloride intracellular channel 1 C00002057
1272 CNTN1, F3, GP135 contactin 1 C00002057
1382 CRABP2, CRABP-II, RBP6 cellular retinoic acid binding protein 2 C00002057
1385 CREB1, CREB cAMP responsive element binding protein 1 C00002057
1437 CSF2, GMCSF colony stimulating factor 2 (granulocyte-macrophage) C00002057
3579 CXCR2, CD182, CDw128b, CMKAR2, IL8R2, IL8RA, IL8RB chemokine (C-X-C motif) receptor 2 C00002057
2833 CXCR3, CD182, CD183, CKR-L2, CMKAR3, GPR9, IP10-R, Mig-R, MigR chemokine (C-X-C motif) receptor 3 C00002057
7852 CXCR4, CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM chemokine (C-X-C motif) receptor 4 C00002057
54205 CYCS, CYC, HCS, THC4 cytochrome c, somatic C00002057
1583 CYP11A1, CYP11A, CYPXIA1, P450SCC cytochrome P450, family 11, subfamily A, polypeptide 1 (EC: C00002057
1544 CYP1A2, CP12, P3-450, P450(PA) cytochrome P450, family 1, subfamily A, polypeptide 2 (EC: C00002057
1592 CYP26A1, CP26, CYP26, P450RAI, P450RAI1 cytochrome P450, family 26, subfamily A, polypeptide 1 (EC:1.14.-.-) C00002057
1553 CYP2A13, CPAD, CYP2A, CYPIIA13 cytochrome P450, family 2, subfamily A, polypeptide 13 (EC: C00002057
1548 CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB cytochrome P450, family 2, subfamily A, polypeptide 6 (EC: C00002057
1555 CYP2B6, CPB6, CYP2B, CYP2B7, CYP2B7P, CYPIIB6, EFVM, IIB1, P450 cytochrome P450, family 2, subfamily B, polypeptide 6 (EC: C00002057
1576 CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 cytochrome P450, family 3, subfamily A, polypeptide 4 (EC: C00002057
1621 DBH, DBM dopamine beta-hydroxylase (dopamine beta-monooxygenase) (EC: C00002057
54876 DCAF16, C4orf30 DDB1 and CUL4 associated factor 16 C00002057
1642 DDB1, DDBA, UV-DDB1, XAP1, XPCE, XPE, XPE-BF damage-specific DNA binding protein 1, 127kDa C00002057
1649 DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153 DNA-damage-inducible transcript 3 C00002057
10521 DDX17, P72, RH70 DEAD (Asp-Glu-Ala-Asp) box helicase 17 (EC: C00002057
9191 DEDD, CASP8IP1, DEDD1, DEFT, FLDED1 death effector domain containing C00002057
1677 DFFB, CAD, CPAN, DFF-40, DFF2, DFF40 DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) C00002057
1719 DHFR, DHFRP1, DYR dihydrofolate reductase (EC: C00002057
1725 DHPS, DHS, DS, MIG13 deoxyhypusine synthase (EC: C00002057
1777 DNASE2, DNASE2A, DNL, DNL2 deoxyribonuclease II, lysosomal (EC: C00002057
10059 DNM1L, DLP1, DRP1, DVLP, DYMPLE, EMPF, HDYNIV dynamin 1-like (EC: C00002057
1841 DTYMK, CDC8, PP3731, TMPK, TYMK deoxythymidylate kinase (thymidylate kinase) (EC: C00002057
1856 DVL2 dishevelled segment polarity protein 2 C00002057
1783 DYNC1LI2, DNCLI2, LIC2 dynein, cytoplasmic 1, light intermediate chain 2 C00002057
1869 E2F1, E2F-1, RBAP1, RBBP3, RBP3 E2F transcription factor 1 C00002057
1870 E2F2, E2F-2 E2F transcription factor 2 C00002057
1871 E2F3, E2F-3 E2F transcription factor 3 C00002057
1874 E2F4, E2F-4 E2F transcription factor 4, p107/p130-binding C00002057
1875 E2F5, E2F-5 E2F transcription factor 5, p130-binding C00002057
1909 EDNRA, ET-A, ETA, ETA-R, ETAR, ETRA, hET-AR endothelin receptor type A C00002057
1938 EEF2, EEF-2, EF-2, EF2, SCA26 eukaryotic translation elongation factor 2 C00002057
1956 EGFR, ERBB, ERBB1, HER1, PIG61, mENA epidermal growth factor receptor (EC: C00002057
5610 EIF2AK2, EIF2AK1, PKR, PRKR eukaryotic translation initiation factor 2-alpha kinase 2 (EC: C00002057
1978 EIF4EBP1, 4E-BP1, 4EBP1, BP-1, PHAS-I eukaryotic translation initiation factor 4E binding protein 1 C00002057
27436 EML4, C2orf2, ELP120, EMAP-4, EMAPL4, ROPP120 echinoderm microtubule associated protein like 4 C00002057
2042 EPHA3, EK4, ETK, ETK1, HEK, HEK4, TYRO4 EPH receptor A3 (EC: C00002057
2049 EPHB3, ETK2, HEK2, TYRO6 EPH receptor B3 (EC: C00002057
2056 EPO, EP, MVCD2 erythropoietin C00002057
7430 EZR, CVIL, CVL, VIL2 ezrin C00002057
2147 F2, PT, RPRGL2, THPH1 coagulation factor II (thrombin) (EC: C00002057
355 FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6 Fas cell surface death receptor C00002057
356 FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6 Fas ligand (TNF superfamily, member 6) C00002057
2195 FAT1, CDHF7, CDHR8, FAT, ME5, hFat1 FAT atypical cadherin 1 C00002057
9638 FEZ1 fasciculation and elongation protein zeta 1 (zygin I) C00002057
2247 FGF2, BFGF, FGF-2, FGFB, HBGF-2 fibroblast growth factor 2 (basic) C00002057
2322 FLT3, CD135, FLK-2, FLK2, STK1 fms-related tyrosine kinase 3 (EC: C00002057
2328 FMO3, FMOII, TMAU, dJ127D3.1 flavin containing monooxygenase 3 (EC: C00002057
2335 FN1, CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF fibronectin 1 C00002057
2348 FOLR1, FBP, FOLR folate receptor 1 (adult) C00002057
2353 FOS, AP-1, C-FOS, p55 FBJ murine osteosarcoma viral oncogene homolog C00002057
2354 FOSB, AP-1, G0S3, GOS3, GOSB FBJ murine osteosarcoma viral oncogene homolog B C00002057
2308 FOXO1, FKH1, FKHR, FOXO1A forkhead box O1 C00002057
2534 FYN, SLK, SYN, p59-FYN FYN oncogene related to SRC, FGR, YES (EC: C00002057
2582 GALE, SDR1E1 UDP-galactose-4-epimerase (EC: C00002057
2624 GATA2, DCML, MONOMAC, NFE1B GATA binding protein 2 C00002057
2643 GCH1, DYT14, DYT5, DYT5a, GCH, GTP-CH-1, GTPCH1, HPABH4B GTP cyclohydrolase 1 (EC: C00002057
2657 GDF1, DORV, DTGA3, RAI growth differentiation factor 1 C00002057
11010 GLIPR1, CRISP7, GLIPR, RTVP1 GLI pathogenesis-related 1 C00002057
2790 GNG10 guanine nucleotide binding protein (G protein), gamma 10 C00002057
2803 GOLGA4, GCP2, GOLG, MU-RMS-40.18, p230 golgin A4 C00002057
2876 GPX1, GPXD, GSHPX1 glutathione peroxidase 1 (EC: C00002057
30206 C00002057
2931 GSK3A glycogen synthase kinase 3 alpha (EC: C00002057
2932 GSK3B glycogen synthase kinase 3 beta (EC: C00002057
2978 GUCA1A, C6orf131, COD3, CORD14, GCAP, GCAP1, GUCA, GUCA1, dJ139D8.6 guanylate cyclase activator 1A (retina) C00002057
3094 HINT1, HINT, NMAN, PKCI-1, PRKCNH1 histidine triad nucleotide binding protein 1 C00002057
6596 HLTF, HIP116, HIP116A, HLTF1, RNF80, SMARCA3, SNF2L3, ZBU1 helicase-like transcription factor C00002057
3159 HMGA1, HMG-R, HMGA1A, HMGIY high mobility group AT-hook 1 C00002057
3156 HMGCR, LDLCQ3 3-hydroxy-3-methylglutaryl-CoA reductase (EC: C00002057
50809 HP1BP3, HP1-BP74 heterochromatin protein 1, binding protein 3 C00002057
3320 HSP90AA1, EL52, HSP86, HSP89A, HSP90A, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2 heat shock protein 90kDa alpha (cytosolic), class A member 1 C00002057
3422 IDI1, IPP1, IPPI1 isopentenyl-diphosphate delta isomerase 1 (EC: C00002057
2537 IFI6, 6-16, FAM14C, G1P3, IFI-6-16, IFI616 interferon, alpha-inducible protein 6 C00002057
3454 IFNAR1, AVP, IFN-alpha-REC, IFNAR, IFNBR, IFRC interferon (alpha, beta and omega) receptor 1 C00002057
3507 C00002057
3586 IL10, CSIF, GVHDS, IL-10, IL10A, TGIF interleukin 10 C00002057
3552 IL1A, IL-1A, IL1, IL1-ALPHA, IL1F1 interleukin 1, alpha C00002057
3553 IL1B, IL-1, IL1-BETA, IL1F2 interleukin 1, beta C00002057
3558 IL2, IL-2, TCGF, lymphokine interleukin 2 C00002057
3563 IL3RA, CD123, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra interleukin 3 receptor, alpha (low affinity) C00002057
3574 IL7, IL-7 interleukin 7 C00002057
3578 IL9, HP40, IL-9, P40 interleukin 9 C00002057
3638 INSIG1, CL-6, CL6 insulin induced gene 1 C00002057
3674 ITGA2B, BDPLT16, BDPLT2, CD41, CD41B, GP2B, GPIIb, GT, GTA, HPA3 integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) C00002057
3683 ITGAL, CD11A, LFA-1, LFA1A integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) C00002057
3688 ITGB1, CD29, FNRB, GPIIA, MDF2, MSK12, VLA-BETA, VLAB integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) C00002057
3690 ITGB3, BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, GT integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) C00002057
3713 IVL involucrin C00002057
80853 KDM7A, JHDM1D lysine (K)-specific demethylase 7A C00002057
3725 JUN, AP-1, AP1, c-Jun jun proto-oncogene C00002057
3726 JUNB, AP-1 jun B proto-oncogene C00002057
8462 KLF11, FKLF, FKLF1, MODY7, TIEG2, Tieg3 Kruppel-like factor 11 C00002057
58508 KMT2C, HALR, MLL3 lysine (K)-specific methyltransferase 2C (EC: C00002057
3912 LAMB1, CLM, LIS5 laminin, beta 1 C00002057
3932 LCK, LSK, YT16, p56lck, pp58lck lymphocyte-specific protein tyrosine kinase (EC: C00002057
3936 LCP1, CP64, L-PLASTIN, LC64P, LPL, PLS2 lymphocyte cytosolic protein 1 (L-plastin) C00002057
3949 LDLR, FH, FHC, LDLCQ2 low density lipoprotein receptor C00002057
3981 LIG4 ligase IV, DNA, ATP-dependent (EC: C00002057
9516 LITAF, PIG7, SIMPLE, TP53I7 lipopolysaccharide-induced TNF factor C00002057
9208 LRRFIP1, FLAP-1, FLAP1, FLIIAP1, GCF-2, GCF2, HUFI-1, TRIP leucine rich repeat (in FLII) interacting protein 1 C00002057
4050 LTB, TNFC, TNFSF3, p33 lymphotoxin beta (TNF superfamily, member 3) C00002057
116068 LYSMD3 LysM, putative peptidoglycan-binding, domain containing 3 C00002057
8567 MADD, DENN, IG20, RAB3GEP MAP-kinase activating death domain C00002057
378938 MALAT1, HCN, LINC00047, MALAT-1, NCRNA00047, NEAT2, PRO2853 metastasis associated lung adenocarcinoma transcript 1 (non-protein coding) C00002057
5594 MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk mitogen-activated protein kinase 1 (EC: C00002057
5595 MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK mitogen-activated protein kinase 3 (EC: C00002057
5599 MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c mitogen-activated protein kinase 8 (EC: C00002057
4170 MCL1, BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT myeloid cell leukemia sequence 1 (BCL2-related) C00002057
80306 MED28, 1500003D12Rik, EG1, magicin mediator complex subunit 28 C00002057
4312 MMP1, CLG, CLGN matrix metallopeptidase 1 (interstitial collagenase) (EC: C00002057
4322 MMP13, CLG3, MANDP1 matrix metallopeptidase 13 (collagenase 3) (EC:3.4.24.-) C00002057
4314 MMP3, CHDS6, MMP-3, SL-1, STMY, STMY1, STR1 matrix metallopeptidase 3 (stromelysin 1, progelatinase) (EC: C00002057
4316 MMP7, MMP-7, MPSL1, PUMP-1 matrix metallopeptidase 7 (matrilysin, uterine) (EC: C00002057
4318 MMP9, CLG4B, GELB, MANDP2, MMP-9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC: C00002057
4485 MST1, D3F15S2, DNF15S2, HGFL, MSP, NF15S2 macrophage stimulating 1 (hepatocyte growth factor-like) C00002057
4528 MTIF2 mitochondrial translational initiation factor 2 C00002057
4605 MYBL2, B-MYB, BMYB v-myb avian myeloblastosis viral oncogene homolog-like 2 C00002057
4609 MYC, MRTL, MYCC, bHLHe39, c-Myc v-myc avian myelocytomatosis viral oncogene homolog C00002057
4637 MYL6, ESMLC, LC17, LC17-GI, LC17-NM, LC17A, LC17B, MLC-3, MLC1SM, MLC3NM, MLC3SM myosin, light chain 6, alkali, smooth muscle and non-muscle C00002057
79923 NANOG Nanog homeobox C00002057
4698 NDUFA5, B13, CI-13KD-B, CI-13kB, NUFM, UQOR13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 (EC: C00002057
4741 NEFM, NEF3, NF-M, NFM neurofilament, medium polypeptide C00002057
4773 NFATC2, NFAT1, NFATP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 C00002057
4790 NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 C00002057
4794 NFKBIE, IKBE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon C00002057
4801 NFYB, CBF-A, CBF-B, HAP3, NF-YB nuclear transcription factor Y, beta C00002057
51199 NIN, SCKL7 ninein (GSK3B interacting protein) C00002057
4832 NME3, DR-nm23, NDPK-C, NDPKC, NM23-H3, NM23H3, c371H6.2 NME/NM23 nucleoside diphosphate kinase 3 (EC: C00002057
4843 NOS2, HEP-NOS, INOS, NOS, NOS2A nitric oxide synthase 2, inducible (EC: C00002057
4846 NOS3, ECNOS, eNOS nitric oxide synthase 3 (endothelial cell) (EC: C00002057
4915 NTRK2, GP145-TrkB, TRKB, trk-B neurotrophic tyrosine kinase, receptor, type 2 (EC: C00002057
8473 OGT, HRNT1, O-GLCNAC O-linked N-acetylglucosamine (GlcNAc) transferase (EC: C00002057
4986 OPRK1, K-OR-1, KOR, KOR-1, OPRK opioid receptor, kappa 1 C00002057
4999 ORC2, ORC2L origin recognition complex, subunit 2 C00002057
79646 PANK3 pantothenate kinase 3 (EC: C00002057
5071 PARK2, AR-JP, LPRS2, PDJ, PRKN parkin RBR E3 ubiquitin protein ligase C00002057
3355109 C00002057
142 PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 poly (ADP-ribose) polymerase 1 (EC: C00002057
5111 PCNA proliferating cell nuclear antigen C00002057
5155 PDGFB, IBGC5, PDGF-2, PDGF2, SIS, SSV, c-sis platelet-derived growth factor beta polypeptide C00002057
5159 PDGFRB, CD140B, IBGC4, IMF1, JTK12, PDGFR, PDGFR-1, PDGFR1 platelet-derived growth factor receptor, beta polypeptide (EC: C00002057
51317 PHF21A, BHC80 PHD finger protein 21A C00002057
23469 PHF3 PHD finger protein 3 C00002057
35178 C00002057
5281 PIGF phosphatidylinositol glycan anchor biosynthesis, class F (EC: C00002057
5290 PIK3CA, CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha (EC: C00002057
5586 PKN2, PAK2, PRK2, PRKCL2, PRO2042, Pak-2 protein kinase N2 (EC: C00002057
5327 PLAT, T-PA, TPA plasminogen activator, tissue (EC: C00002057
5328 PLAU, ATF, BDPLT5, QPD, UPA, URK, u-PA plasminogen activator, urokinase (EC: C00002057
5329 PLAUR, CD87, U-PAR, UPAR, URKR plasminogen activator, urokinase receptor C00002057
5337 PLD1 phospholipase D1, phosphatidylcholine-specific (EC: C00002057
5338 PLD2 phospholipase D2 (EC: C00002057
57480 PLEKHG1, ARHGEF41 pleckstrin homology domain containing, family G (with RhoGef domain) member 1 C00002057
5409 PNMT, PENT, PNMTase phenylethanolamine N-methyltransferase (EC: C00002057
8228 PNPLA4, DXS1283E, GS2, iPLA2eta patatin-like phospholipase domain containing 4 (EC: C00002057
5445 PON2 paraoxonase 2 (EC: C00002057
5450 POU2AF1, BOB1, OBF-1, OBF1, OCAB POU class 2 associating factor 1 C00002057
5451 POU2F1, OCT1, OTF1, oct-1B POU class 2 homeobox 1 C00002057
5460 POU5F1, OCT3, OCT4, OTF-3, OTF3, OTF4, Oct-3, Oct-4 POU class 5 homeobox 1 C00002057
5523 PPP2R3A, PPP2R3, PR130, PR72 protein phosphatase 2, regulatory subunit B'', alpha (EC: C00002057
5577 PRKAR2B, PRKAR2, RII-BETA protein kinase, cAMP-dependent, regulatory, type II, beta (EC: C00002057
5578 PRKCA, AAG6, PKC-alpha, PKCA, PRKACA protein kinase C, alpha (EC: C00002057
5579 PRKCB, PKC-beta, PKCB, PRKCB1, PRKCB2 protein kinase C, beta (EC: C00002057
5589 PRKCSH, AGE-R2, G19P1, PCLD, PKCSH, PLD1 protein kinase C substrate 80K-H (EC: C00002057
5590 PRKCZ, PKC-ZETA, PKC2 protein kinase C, zeta (EC: C00002057
55119 PRPF38B, NET1, RP11-293A10.1 pre-mRNA processing factor 38B C00002057
23215 PRRC2C, BAT2-iso, BAT2D1, BAT2L2, XTP2 proline-rich coiled-coil 2C C00002057
5644 PRSS1, TRP1, TRY1, TRY4, TRYP1 protease, serine, 1 (trypsin 1) (EC: C00002057
5694 PSMB6, DELTA, LMPY, Y proteasome (prosome, macropain) subunit, beta type, 6 (EC: C00002057
5724 PTAFR, PAFR platelet-activating factor receptor C00002057
58155 PTBP2, PTB, PTBLP, brPTB, nPTB, nPTB5, nPTB6, nPTB7, nPTB8 polypyrimidine tract binding protein 2 C00002057
5786 PTPRA, HEPTP, HLPR, HPTPA, HPTPalpha, LRP, PTPA, PTPRL2, R-PTP-alpha, RPTPA protein tyrosine phosphatase, receptor type, A (EC: C00002057
5806 PTX3, TNFAIP5, TSG-14 pentraxin 3, long C00002057
5870 RAB6A, RAB6 RAB6A, member RAS oncogene family C00002057
5894 RAF1, CRAF, NS5, Raf-1, c-Raf v-raf-1 murine leukemia viral oncogene homolog 1 (EC: C00002057
5916 RARG, NR1B3, RARC retinoic acid receptor, gamma C00002057
5925 RB1, OSRC, RB, p105-Rb, pRb, pp110 retinoblastoma 1 C00002057
5930 RBBP6, MY038, P2P-R, PACT, RBQ-1, SNAMA retinoblastoma binding protein 6 C00002057
146713 RBFOX3, FOX-3, FOX3, HRNBP3, NEUN RNA binding protein, fox-1 homolog (C. elegans) 3 C00002057
5933 RBL1, CP107, PRB1, p107 retinoblastoma-like 1 (p107) C00002057
5934 RBL2, P130, Rb2 retinoblastoma-like 2 (p130) C00002057
58517 RBM25, NET52, RED120, RNPC7, S164, Snu71, fSAP94 RNA binding motif protein 25 C00002057
5970 RELA, NFKB3, p65 v-rel avian reticuloendotheliosis viral oncogene homolog A C00002057
5994 RFXAP regulatory factor X-associated protein C00002057
5996 RGS1, 1R20, BL34, IER1, IR20 regulator of G-protein signaling 1 C00002057
6018 RLF, ZN-15L, ZNF292L rearranged L-myc fusion C00002057
6130 RPL7A, L7A, SURF3, TRUP ribosomal protein L7a C00002057
6230 RPS25, S25 ribosomal protein S25 C00002057
57521 RPTOR, KOG1, Mip1 regulatory associated protein of MTOR, complex 1 C00002057
862 RUNX1T1, AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) C00002057
6281 S100A10, 42C, ANX2L, ANX2LG, CAL1L, CLP11, Ca[1], GP11, P11, p10 S100 calcium binding protein A10 C00002057
44263 C00002057
66234 C00002057
9169 SCAF11, CASP11, SFRS2IP, SIP1, SRRP129, SRSF2IP SR-related CTD-associated factor 11 C00002057
23480 SEC61G, SSS1 Sec61 gamma subunit C00002057
10955 SERINC3, AIGP1, DIFF33, SBBI99, TDE, TDE1, TMS-1 serine incorporator 3 C00002057
5054 SERPINE1, PAI, PAI-1, PAI1, PLANH1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 C00002057
871 SERPINH1, AsTP3, CBP1, CBP2, HSP47, OI10, PPROM, RA-A47, SERPINH2, gp46 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) C00002057
51639 SF3B14, HSPC175, Ht006, P14, SAP14, SF3B14a splicing factor 3B, 14 kDa subunit C00002057
10572 SIVA1, CD27BP, SIVA, Siva-1, Siva-2 SIVA1, apoptosis-inducing factor C00002057
6573 SLC19A1, CHMD, FOLT, IFC1, REFC, RFC1 solute carrier family 19 (folate transporter), member 1 C00002057
10559 SLC35A1, CDG2F, CMPST, CST, hCST solute carrier family 35 (CMP-sialic acid transporter), member A1 C00002057
25800 SLC39A6, LIV-1 solute carrier family 39 (zinc transporter), member 6 C00002057
9351 SLC9A3R2, E3KARP, NHE3RF2, NHERF-2, NHERF2, OCTS2, SIP-1, SIP1, TKA-1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 C00002057
4093 SMAD9, MADH6, MADH9, PPH2, SMAD8, SMAD8A, SMAD8B SMAD family member 9 C00002057
6615 SNAI1, SLUGH2, SNA, SNAH, SNAIL, SNAIL1, dJ710H13.1 snail family zinc finger 1 C00002057
6591 SNAI2, SLUG, SLUGH1, SNAIL2, WS2D snail family zinc finger 2 C00002057
6619 SNAPC3, PTFbeta, SNAP50 small nuclear RNA activating complex, polypeptide 3, 50kDa C00002057
6622 SNCA, NACP, PARK1, PARK4, PD1 synuclein, alpha (non A4 component of amyloid precursor) C00002057
252672 C00002057
6647 SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer superoxide dismutase 1, soluble (EC: C00002057
6654 SOS1, GF1, GGF1, GINGF, HGF, NS4 son of sevenless homolog 1 (Drosophila) C00002057
9043 SPAG9, CT89, HLC-6, HLC4, JIP-4, JIP4, JLP, PHET, PIG6 sperm associated antigen 9 C00002057
6696 SPP1, BNSP, BSPI, ETA-1, OPN secreted phosphoprotein 1 C00002057
6714 SRC, ASV, SRC1, c-SRC, p60-Src v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (EC: C00002057
6720 SREBF1, SREBP-1c, SREBP1, bHLHd1 sterol regulatory element binding transcription factor 1 C00002057
400410 ST20, HCCS-1 suppressor of tumorigenicity 20 C00002057
6770 STAR, STARD1 steroidogenic acute regulatory protein C00002057
6773 STAT2, ISGF-3, P113, STAT113 signal transducer and activator of transcription 2, 113kDa C00002057
6774 STAT3, APRF, HIES signal transducer and activator of transcription 3 (acute-phase response factor) C00002057
6777 STAT5B, STAT5 signal transducer and activator of transcription 5B C00002057
6778 STAT6, D12S1644, IL-4-STAT, STAT6B, STAT6C signal transducer and activator of transcription 6, interleukin-4 induced C00002057
8614 STC2, STC-2, STCRP stanniocalcin 2 C00002057
10963 STIP1, HOP, IEF-SSP-3521, P60, STI1, STI1L stress-induced-phosphoprotein 1 C00002057
10494 STK25, SOK1, YSK1 serine/threonine kinase 25 (EC: C00002057
10036 CHAF1A, CAF-1, CAF1, CAF1B, CAF1P150, P150 chromatin assembly factor 1, subunit A (p150) C00002020
6827 SUPT4H1, SPT4, SPT4H, SUPT4H suppressor of Ty 4 homolog 1 (S. cerevisiae) C00002057
8407 TAGLN2, HA1756 transgelin 2 C00002057
57551 TAOK1, KFC-B, MAP3K16, MARKK, PSK-2, PSK2, TAO1, hKFC-B, hTAOK1 TAO kinase 1 (EC: C00002057
7027 TFDP1, DP1, DRTF1, Dp-1 transcription factor Dp-1 C00002057
7980 TFPI2, PP5, REF1, TFPI-2 tissue factor pathway inhibitor 2 C00002057
7037 TFRC, CD71, T9, TFR, TFR1, TR, TRFR, p90 transferrin receptor C00002057
7054 TH, DYT14, DYT5b, TYH tyrosine hydroxylase (EC: C00002057
9984 THOC1, HPR1, P84, P84N5 THO complex 1 C00002057
7078 TIMP3, HSMRK222, K222, K222TA2, SFD TIMP metallopeptidase inhibitor 3 C00002057
7079 TIMP4 TIMP metallopeptidase inhibitor 4 C00002057
7082 TJP1, ZO-1 tight junction protein 1 C00002057
440026 TMEM41B transmembrane protein 41B C00002057
7124 TNF, DIF, TNF-alpha, TNFA, TNFSF2 tumor necrosis factor C00002057
7132 TNFRSF1A, CD120a, FPF, MS5, TBP1, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR1-d2, TNFR55, TNFR60, p55, p55-R, p60 tumor necrosis factor receptor superfamily, member 1A C00002057
11073 TOPBP1, TOP2BP1 topoisomerase (DNA) II binding protein 1 C00002057
7175 TPR translocated promoter region, nuclear basket protein C00002057
29896 TRA2A, AWMS1, HSU53209 transformer 2 alpha homolog (Drosophila) C00002057
28951 TRIB2, C5FW, GS3955, TRB2 tribbles pseudokinase 2 C00002057
9321 TRIP11, ACG1A, CEV14, GMAP-210, TRIP-11, TRIP230 thyroid hormone receptor interactor 11 C00002057
7253 TSHR, CHNG1, LGR3, hTSHR-I thyroid stimulating hormone receptor C00002057
7277 TUBA4A, H2-ALPHA, TUBA1 tubulin, alpha 4a C00002057
203068 TUBB, M40, OK/SW-cl.56, TUBB1, TUBB5 tubulin, beta class I C00002057
7291 TWIST1, ACS3, BPES2, BPES3, CRS1, SCS, TWIST, bHLHa38 twist family bHLH transcription factor 1 C00002057
10190 TXNDC9, APACD, PHLP3 thioredoxin domain containing 9 C00002057
23350 U2SURP, SR140, fSAPa U2 snRNP-associated SURP domain containing C00002057
10054 UBA2, ARX, SAE2 ubiquitin-like modifier activating enzyme 2 C00002057
11065 UBE2C, UBCH10, dJ447F3.2 ubiquitin-conjugating enzyme E2C (EC: C00002057
7329 UBE2I, C358B7.1, P18, UBC9 ubiquitin-conjugating enzyme E2I (EC: C00002057
7337 UBE3A, ANCR, AS, E6-AP, EPVE6AP, HPVE6A ubiquitin protein ligase E3A (EC: C00002057
51569 UFM1, BM-002, C13orf20 ubiquitin-fold modifier 1 C00002057
7360 UGP2, UDPG, UDPGP, UDPGP2, UGP1, UGPP1, UGPP2, pHC379 UDP-glucose pyrophosphorylase 2 (EC: C00002057
54659 UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C UDP glucuronosyltransferase 1 family, polypeptide A3 (EC: C00002057
54657 UGT1A4, HUG-BR2, UDPGT, UDPGT_1-4, UGT-1D, UGT1-04, UGT1.4, UGT1D UDP glucuronosyltransferase 1 family, polypeptide A4 (EC: C00002057
54600 UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I UDP glucuronosyltransferase 1 family, polypeptide A9 (EC: C00002057
9094 UNC119, HRG4, POC7, POC7A unc-119 homolog (C. elegans) C00002057
7386 UQCRFS1, RIP1, RIS1, RISP, UQCR5 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 (EC: C00002057
7412 VCAM1, CD106, INCAM-100 vascular cell adhesion molecule 1 C00002057
7422 VEGFA, MVCD1, VEGF, VPF vascular endothelial growth factor A C00002057
7431 VIM, CTRCT30 vimentin C00002057
7450 VWF, F8VWF, VWD von Willebrand factor C00002057
331 XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3 X-linked inhibitor of apoptosis C00002057
7503 XIST, DXS1089, DXS399E, LINC00001, NCRNA00001, SXI1, swd66 X inactive specific transcript (non-protein coding) C00002057
7525 YES1, HsT441, P61-YES, Yes, c-yes v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 (EC: C00002057
23318 ZCCHC11, PAPD3, TUT4 zinc finger, CCHC domain containing 11 (EC: C00002057
84240 ZCCHC9, PPP1R41 zinc finger, CCHC domain containing 9 C00002057
6935 ZEB1, AREB6, BZP, DELTAEF1, FECD6, NIL2A, PPCD3, TCF8, ZFHEP, ZFHX1A zinc finger E-box binding homeobox 1 C00002057
7538 ZFP36, G0S24, GOS24, NUP475, RNF162A, TIS11, TTP, zfp-36 ZFP36 ring finger protein C00002057
51663 ZFR, ZFR1 zinc finger RNA binding protein C00002057
23613 ZMYND8, PRKCBP1, PRO2893, RACK7 zinc finger, MYND-type containing 8 C00002057
7705 ZNF146, OZF zinc finger protein 146 C00002057
100129482 ZNF37BP, KOX21, ZNF37B zinc finger protein 37B, pseudogene C00002057
90333 ZNF468 zinc finger protein 468 C00002057
100289635 ZNF605 zinc finger protein 605 C00002057
100129842 ZNF737, ZNF102 zinc finger protein 737 C00002057

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (84)

OMIM preferred title UniProt
#100100 Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism P20309
#103780 Alcohol dependence P08172
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#614373 Amyotrophic lateral sclerosis 16, juvenile; als16 Q99720
#602025 Body mass index quantitative trait locus 9; bmiq9 P41968
#300615 Brunner syndrome P21397
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#212140 Carnitine deficiency, systemic primary; cdsp O76082
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#114500 Colorectal cancer; crc P84022
#162800 Cyclic neutropenia P08246
#612522 Diabetes mellitus, insulin-dependent, 22; iddm22 P51681
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#237500 Dubin-johnson syndrome; djs Q92887
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#600513 Epilepsy, nocturnal frontal lobe, 1; enfl1 P43681
#605375 Epilepsy, nocturnal frontal lobe, 3; enfl3 P17787
#610353 Epilepsy, nocturnal frontal lobe, 4; enfl4 Q15822
#615040 Episodic pain syndrome, familial, 1; feps1 O75762
#615363 Estrogen resistance; estrr P03372
#600274 Frontotemporal dementia; ftd P10636
#613659 Gastric cancer P04626
#137215 Gastric cancer, hereditary diffuse; hdgc P04626
#231095 Ghosal hematodiaphyseal dysplasia; ghdd P24557
#137800 Glioma susceptibility 1; glm1 P04626
#610140 Heart-hand syndrome, slovenian type P02545
#609423 Human immunodeficiency virus type 1, susceptibility to P41597
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#237450 Hyperbilirubinemia, rotor type; hblrr Q9NPD5
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#603932 Intervertebral disc disease; idd P14780
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#613688 Long qt syndrome 2; lqt2 Q12809
#211980 Lung cancer P00533
#608516 Major depressive disorder; mdd P08172
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
%300852 Mental retardation, x-linked 88; mrx88 P50052
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#603933 Microvascular complications of diabetes, susceptibility to, 1; mvcd1 P15692
#259600 Multicentric osteolysis, nodulosis, and arthropathy; mona P08253
#265000 Multiple pterygium syndrome, escobar variant; evmps P07510
#253290 Multiple pterygium syndrome, lethal type; lmps P02708
#126200 Multiple sclerosis, susceptibility to; ms P08575
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#608931 Myasthenic syndrome, congenital, associated with acetylcholine receptor deficiency P11230
#608930 Myasthenic syndrome, congenital, fast-channel P02708
#601462 Myasthenic syndrome, congenital, slow-channel; sccms P02708
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#159900 Myoclonic dystonia P14416
#202700 Neutropenia, severe congenital, 1, autosomal dominant; scn1 P08246
#601665 Obesity P32245
#164230 Obsessive-compulsive disorder; ocd P31645
#604715 Orthostatic intolerance P23975
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#167000 Ovarian cancer P04626
#260540 Parkinson-dementia syndrome P10636
#613135 Parkinsonism-dystonia, infantile; pkdys Q01959
#172700 Pick disease of brain P10636
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#607276 Resting heart rate, variation in P08588
#275210 Restrictive dermopathy, lethal P02545
#180300 Rheumatoid arthritis; ra Q9H015
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#608971 Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive P08575
#609620 Short qt syndrome 1; sqt1 Q12809
#612052 Smoking as a quantitative trait locus 3; sqtl3 P30532
#605361 Spinocerebellar ataxia 14; sca14 P05129
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#601367 Stroke, ischemic P24723
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#190300 Tremor, hereditary essential, 1; etm1 P35462
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#610379 West nile virus, susceptibility to P51681
#112100 Yt blood group antigen P22303


KEGG name UniProt
H00286 Crohn's disease O76082 (related)
Q9H015 (related)
H00525 Disorders of fatty-acid oxidation O76082 (related)
H00016 Oral cancer P00533 (related)
P00533 (marker)
H00017 Esophageal cancer P00533 (related)
P35354 (related)
H00018 Gastric cancer P00533 (related)
P04626 (related)
P15692 (related)
H00022 Bladder cancer P00533 (related)
P04626 (related)
H00028 Choriocarcinoma P00533 (related)
P03956 (related)
P04626 (related)
P08253 (related)
H00030 Cervical cancer P00533 (related)
P04626 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00770 Congenital myasthenic syndrome P02708 (related)
P11230 (related)
Q07001 (related)
H00986 Multiple pterygium syndrome P02708 (related)
P07510 (related)
Q07001 (related)
H00026 Endometrial Cancer P03372 (marker)
P04626 (related)
Q92731 (marker)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00019 Pancreatic cancer P04626 (related)
H00027 Ovarian cancer P04626 (related)
H00031 Breast cancer P04626 (related)
P04626 (marker)
H00046 Cholangiocarcinoma P04626 (related)
P35354 (related)
H00063 Spinocerebellar ataxia (SCA) P05129 (related)
Q9NUW8 (related)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00079 Asthma P07550 (related)
H00100 Neutropenic disorders P08246 (related)
H00025 Penile cancer P08253 (related)
P14780 (related)
P35354 (related)
H00472 Torg-Winchester syndrome P08253 (related)
H00091 T-B+Severe combined immunodeficiencies (SCIDs) P08575 (related)
H00036 Osteosarcoma P08684 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
Q13148 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H01205 Coumarin resistance P11712 (related)
H00479 Metaphyseal dysplasias P14780 (related)
H00021 Renal cell carcinoma P15692 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00807 Autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) P17787 (related)
P43681 (related)
Q15822 (related)
H00548 Brunner syndrome P21397 (related)
H01031 Orthostatic intolerance (OI) P23975 (related)
H00490 Diaphyseal dysplasia with anemia (Ghosal) P24557 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00480 Non-syndromic X-linked mental retardation P50052 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00408 Type I diabetes mellitus Q04759 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)
H00208 Hyperbilirubinemia Q92887 (related)

Diseases related to CTD interactions

204 disease in interactions with metabolites

D000647 Amnesia C00002020
D001919 Bradycardia C00002020
D014202 Tremor C00002020
D010243 Paralysis C00002020
D002375 Catalepsy C00002020
D019954 Neurobehavioral Manifestations C00002020
D009374 Neoplasms, Experimental C00002020
D007022 Hypotension C00002020
D055752 Small Cell Lung Carcinoma C00002057
D009062 Mouth Neoplasms C00002020
D009127 Muscle Rigidity C00002020
D006965 Hyperplasia C00002020
D020820 Dyskinesias C00002020
D009914 Oral Submucous Fibrosis C00002020
D010212 Papilloma C00002020
D002280 Carcinoma, Basal Cell C00002020
D020734 Parkinsonian Disorders C00002020
D011470 Prostatic Hyperplasia C00002020
D013226 Status Epilepticus C00002020
D014062 Tongue Neoplasms C00002020
D002277 Carcinoma C00002020
D015746 Abdominal Pain C00002057
D000014 Abnormalities, Drug-Induced C00002057
D058186 Acute Kidney Injury C00002057
D000405 Akinetic Mutism C00002057
D000437 Alcoholism C00002057
D000544 Alzheimer Disease C00002057
D019969 Amphetamine-Related Disorders C00002057
D017542 Aneurysm, Ruptured C00002057
D000860 Anoxia C00002057
D001008 Anxiety Disorders C00002057
D001014 Aortic Aneurysm C00002057
D001018 Aortic Diseases C00002057
D001049 Apnea C00002057
D001145 Arrhythmias, Cardiac C00002057
D001161 Arteriosclerosis C00002057
D001168 Arthritis C00002057
D001176 Arthrogryposis C00002057
D001259 Ataxia C00002057
D050197 Atherosclerosis C00002057
D001281 Atrial Fibrillation C00002057
D054537 Atrioventricular Block C00002057
D001289 Attention Deficit Disorder with Hyperactivity C00002057
D001308 Auditory Perceptual Disorders C00002057
D001714 Bipolar Disorder C00002057
D001927 Brain Diseases C00002057
D001929 Brain Edema C00002057
D001930 Brain Injuries C00002057
D001943 Breast Neoplasms C00002057
D002114 Calcinosis C00002057
D002289 Carcinoma, Non-Small-Cell Lung C00002057
D002294 Carcinoma, Squamous Cell C00002057
D005117 Cardiac Complexes, Premature C00002057
D009202 Cardiomyopathies C00002057
D002318 Cardiovascular Diseases C00002057
D002543 Cerebral Hemorrhage C00002057
D002561 Cerebrovascular Disorders C00002057
D018290 Cervical Intraepithelial Neoplasia C00002057
D002637 Chest Pain C00002057
D019970 Cocaine-Related Disorders C00002057
D003072 Cognition Disorders C00002057
D003093 Colitis, Ulcerative C00002057
D003110 Colonic Neoplasms C00002057
D019955 Conduct Disorder C00002057
D003251 Constriction, Pathologic C00002057
D003324 Coronary Artery Disease C00002057
D003329 Coronary Vasospasm C00002057
D003490 Cyanosis C00002057
D003693 Delirium C00002057
D003866 Depressive Disorder C00002057
D003865 Depressive Disorder, Major C00002057
D003872 Dermatitis C00002057
D003924 Diabetes Mellitus, Type 2 C00002057
D003928 Diabetic Nephropathies C00002057
D003967 Diarrhea C00002057
D004244 Dizziness C00002057
D056486 Drug-Induced Liver Injury C00002057
D064420 Drug-Related Side Effects and Adverse Reactions C00002057
D004409 Dyskinesia, Drug-Induced C00002057
D004421 Dystonia C00002057
D020821 Dystonic Disorders C00002057
D001068 Eating Disorders C00002057
D004487 Edema C00002057
D004802 Eosinophilia C00002057
D007172 Erectile Dysfunction C00002057
D004890 Erythema C00002057
D005076 Exanthema C00002057
D005234 Fatty Liver C00002057
D005317 Fetal Growth Retardation C00002057
D005334 Fever C00002057
D005921 Glomerulonephritis C00002057
D044882 Glucose Metabolism Disorders C00002057
D006261 Headache C00002057
D006258 Head and Neck Neoplasms C00002057
D006323 Heart Arrest C00002057
D006606 Hiccup C00002057
D006930 Hyperalgesia C00002057
D006940 Hyperemia C00002057
D006948 Hyperkinesis C00002057
D006973 Hypertension C00002057
D006976 Hypertension, Pulmonary C00002057
D006984 Hypertrophy C00002057
D006985 Hyperventilation C00002057
D018476 Hypokinesia C00002057
D007035 Hypothermia C00002057
D007246 Infertility C00002057
D007249 Inflammation C00002057
D007333 Insulin Resistance C00002057
D055959 Intervertebral Disc Degeneration C00002057
D002542 Intracranial Embolism and Thrombosis C00002057
D007511 Ischemia C00002057
D007805 Language Development Disorders C00002057
D007859 Learning Disorders C00002057
D008107 Liver Diseases C00002057
D008133 Long QT Syndrome C00002057
D008171 Lung Diseases C00002057
D008175 Lung Neoplasms C00002057
D008545 Melanoma C00002057
D008569 Memory Disorders C00002057
D028361 Mitochondrial Diseases C00002057
D009041 Motion Sickness C00002057
D009069 Movement Disorders C00002057
D020267 MPTP Poisoning C00002057
D009133 Muscular Atrophy C00002057
D009203 Myocardial Infarction C00002057
D015428 Myocardial Reperfusion Injury C00002057
D009207 Myoclonus C00002057
D009325 Nausea C00002057
D009336 Necrosis C00002057
D009361 Neoplasm Invasiveness C00002057
D009362 Neoplasm Metastasis C00002057
D009369 Neoplasms C00002057
D009389 Neovascularization, Pathologic C00002057
D009410 Nerve Degeneration C00002057
D009422 Nervous System Diseases C00002057
D009436 Neural Tube Defects C00002057
D019636 Neurodegenerative Diseases C00002057
D054081 Neuronal Migration Disorders C00002057
D020258 Neurotoxicity Syndromes C00002057
D009669 Nose Neoplasms C00002057
D009759 Nystagmus, Pathologic C00002057
D009765 Obesity C00002057
D009845 Oligospermia C00002057
D010146 Pain C00002057
D010182 Pancreatic Diseases C00002057
D010190 Pancreatic Neoplasms C00002057
D016584 Panic Disorder C00002057
D030361 Papillomavirus Infections C00002057
D010291 Paresis C00002057
D010302 Parkinson Disease, Secondary C00002057
D010510 Periodontal Diseases C00002057
D010523 Peripheral Nervous System Diseases C00002057
D016491 Peripheral Vascular Diseases C00002057
D011041 Poisoning C00002057
D011086 Polycythemia C00002057
D011183 Postoperative Complications C00002057
D011297 Prenatal Exposure Delayed Effects C00002057
D003668 Pressure Ulcer C00002057
D011507 Proteinuria C00002057
D011537 Pruritus C00002057
D011605 Psychoses, Substance-Induced C00002057
D011618 Psychotic Disorders C00002057
D011654 Pulmonary Edema C00002057
D011693 Purpura C00002057
D012021 Reflex, Abnormal C00002057
D051436 Renal Insufficiency, Chronic C00002057
D015427 Reperfusion Injury C00002057
D012120 Respiration Disorders C00002057
D012131 Respiratory Insufficiency C00002057
D015619 Respiratory System Abnormalities C00002057
D012164 Retinal Diseases C00002057
D012640 Seizures C00002057
D012798 Sialorrhea C00002057
D012848 Sinoatrial Block C00002057
D012878 Skin Neoplasms C00002057
D012893 Sleep Disorders C00002057
D007319 Sleep Initiation and Maintenance Disorders C00002057
D007153 Immunologic Deficiency Syndromes C00002020
D013035 Spasm C00002057
D016137 Spina Bifida Cystica C00002057
D013117 Spinal Cord Compression C00002057
D019956 Stereotypic Movement Disorder C00002057
D013274 Stomach Neoplasms C00002057
D013276 Stomach Ulcer C00002057
D020521 Stroke C00002057
D013345 Subarachnoid Hemorrhage C00002057
D019966 Substance-Related Disorders C00002057
D013375 Substance Withdrawal Syndrome C00002057
D013398 Sudden Infant Death C00002057
D013610 Tachycardia C00002057
D013919 Thromboangiitis Obliterans C00002057
D013927 Thrombosis C00002057
D020323 Tics C00002057
D014029 Tobacco Use Disorder C00002057
D005879 Tourette Syndrome C00002057
D014133 Tracheal Diseases C00002057
D001745 Urinary Bladder Diseases C00002057
D014652 Vascular Diseases C00002057
D014657 Vasculitis C00002057
D018366 Vasculitis, Leukocytoclastic, Cutaneous C00002057
D018879 Ventricular Premature Complexes C00002057
D014839 Vomiting C00002057
D015430 Weight Gain C00002057