KNApSAcK Metabolite C00002043
Metabolite
KNApSAcK Entry
| id | C00002043 |
|---|---|
| Name | Guvacine |
| CAS RN | 498-96-4 |
| Standard InChI | InChI=1S/C6H9NO2/c8-6(9)5-2-1-3-7-4-5/h2,7H,1,3-4H2,(H,8,9) |
| Standard InChI (Main Layer) | InChI=1S/C6H9NO2/c8-6(9)5-2-1-3-7-4-5/h2,7H,1,3-4H2,(H,8,9) |
Cluster
| Phytochemical cluster | No. 1 |
|---|---|
| KCF-S cluster | No. 5088 |
Link
ChEMBL
| By standard InChI | CHEMBL76768 |
|---|---|
| By standard InChI Main Layer | CHEMBL76768 |
KEGG
| By LinkDB | C10149 |
|---|
CTD
| By CAS RN | C015910 |
|---|
Species
Summary
Plant class
| class name | count |
|---|---|
| Liliopsida | 1 |
Family
| family name | count |
|---|---|
| Arecaceae | 1 |
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Areca catechu | 184783 | Arecaceae | Liliopsida | Viridiplantae |
Human Protein / Gene in interaction
13 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| P48066 | Sodium- and chloride-dependent GABA transporter 3 | GABA | CHEMBL76768 |
CHEMBL679557
(1)
CHEMBL1166721
(1)
|
0 / 0 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | CHEMBL76768 |
CHEMBL1741321
(2)
|
1 / 0 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | CHEMBL76768 |
CHEMBL1738091
(1)
|
0 / 0 |
| P30531 | Sodium- and chloride-dependent GABA transporter 1 | GABA | CHEMBL76768 |
CHEMBL806333
(1)
|
0 / 0 |
| Q9NSD5 | Sodium- and chloride-dependent GABA transporter 2 | GABA | CHEMBL76768 |
CHEMBL1166722
(1)
|
0 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | CHEMBL76768 |
CHEMBL1614281
(1)
CHEMBL1614361
(1)
|
3 / 2 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | CHEMBL76768 |
CHEMBL1741325
(2)
|
0 / 1 |
| P48065 | Sodium- and chloride-dependent betaine transporter | Betaine and GABA Na-symporter | CHEMBL76768 |
CHEMBL806334
(1)
|
0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | CHEMBL76768 |
CHEMBL1738610
(1)
|
0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | CHEMBL76768 |
CHEMBL1741322
(2)
|
0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | CHEMBL76768 |
CHEMBL1741323
(2)
|
1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | CHEMBL76768 |
CHEMBL1741324
(2)
|
0 / 1 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | CHEMBL76768 |
CHEMBL1738442
(1)
|
0 / 0 |
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (5)
| OMIM | preferred title | UniProt |
|---|---|---|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|