KNApSAcK Metabolite C00025885
Metabolite
KNApSAcK Entry
| id | C00025885 |
|---|---|
| Name | Hayatine / (+/-)-Curine / (+/-)-Bebeerine |
| CAS RN | 26057-51-2 |
| Standard InChI | InChI=1S/C36H38N2O6/c1-37-13-11-23-18-31(41-3)32-20-26(23)27(37)15-21-5-8-25(9-6-21)43-36-34-24(19-33(42-4)35(36)40)12-14-38(2)28(34)16-22-7-10-29(39)30(17-22)44-32/h5-10,17-20,27-28,39-40H,11-16H2,1-4H3/t27-,28-/m1/s1 |
| Standard InChI (Main Layer) | InChI=1S/C36H38N2O6/c1-37-13-11-23-18-31(41-3)32-20-26(23)27(37)15-21-5-8-25(9-6-21)43-36-34-24(19-33(42-4)35(36)40)12-14-38(2)28(34)16-22-7-10-29(39)30(17-22)44-32/h5-10,17-20,27-28,39-40H,11-16H2,1-4H3 |
Cluster
| Phytochemical cluster | No. 4 |
|---|---|
| KCF-S cluster | No. 10 |
Link
ChEMBL
| By standard InChI | CHEMBL1169627 |
|---|---|
| By standard InChI Main Layer | CHEMBL1169627 |
KEGG
| By LinkDB |
|---|
CTD
| By CAS RN |
|---|
Species
Summary
Plant class
| class name | count |
|---|---|
| eudicotyledons | 1 |
Family
| family name | count |
|---|---|
| Menispermaceae | 1 |
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Cissampelos pareira L. | 108409 | Menispermaceae | eudicotyledons | Viridiplantae |
Human Protein / Gene in interaction
13 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | CHEMBL1169627 |
CHEMBL1738312
(1)
|
0 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | CHEMBL1169627 |
CHEMBL2114784
(1)
|
1 / 1 |
| P47898 | 5-hydroxytryptamine receptor 5A | Serotonin receptor | CHEMBL1169627 |
CHEMBL1794491
(1)
|
0 / 0 |
| P42858 | Huntingtin | Unclassified protein | CHEMBL1169627 |
CHEMBL1613918
(1)
|
1 / 1 |
| O75496 | Geminin | Unclassified protein | CHEMBL1169627 |
CHEMBL2114843
(1)
CHEMBL2114780
(2)
|
0 / 0 |
| P41143 | Delta-type opioid receptor | Opioid receptor | CHEMBL1169627 |
CHEMBL1794452
(1)
CHEMBL1794484
(1)
|
0 / 0 |
| P35372 | Mu-type opioid receptor | Opioid receptor | CHEMBL1169627 |
CHEMBL1794457
(1)
CHEMBL1794484
(1)
|
0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | CHEMBL1169627 |
CHEMBL1737991
(1)
|
0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | CHEMBL1169627 |
CHEMBL1614421
(1)
|
4 / 3 |
| O43603 | Galanin receptor type 2 | Galanin receptor | CHEMBL1169627 |
CHEMBL1614350
(1)
CHEMBL1614422
(1)
|
0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | CHEMBL1169627 |
CHEMBL1794536
(1)
|
0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | CHEMBL1169627 |
CHEMBL1738442
(1)
|
0 / 0 |
| P43351 | DNA repair protein RAD52 homolog | Unclassified protein | CHEMBL1169627 |
CHEMBL2354285
(1)
|
0 / 0 |
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (6)
| OMIM | preferred title | UniProt |
|---|---|---|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #143100 | Huntington disease; hd |
P42858
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
KEGG DISEASE (5)
| KEGG | disease name | UniProt |
|---|---|---|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00059 | Huntington's disease (HD) |
P42858
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|