PCIDB

KNApSAcK Metabolite C00000269

Metabolite

KNApSAcK Entry

id C00000269
Name Nagilactone B
CAS RN 19891-51-1
Standard InChI InChI=1S/C19H24O7/c1-7(2)13-11-8(5-10(21)25-13)19(4)15-14(12(11)22)26-17(24)18(15,3)6-9(20)16(19)23/h5,7,9,12,14-16,20,22-23H,6H2,1-4H3/t9-,12-,14-,15+,16-,18+,19-/m1/s1
Standard InChI (Main Layer) InChI=1S/C19H24O7/c1-7(2)13-11-8(5-10(21)25-13)19(4)15-14(12(11)22)26-17(24)18(15,3)6-9(20)16(19)23/h5,7,9,12,14-16,20,22-23H,6H2,1-4H3

Cluster

Phytochemical cluster No. 41
KCF-S cluster No. 1854

Link

ChEMBL

By standard InChI
By standard InChI Main Layer CHEMBL1586581

KEGG

By LinkDB

CTD

By CAS RN

Species

Summary

Plant class

class name count
Spermatophyta 2

Family

family name count
Podocarpaceae 2

List (2)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Podocarpus nagai 36012 Podocarpaceae Spermatophyta Viridiplantae
Podocarpus nagi 36012 Podocarpaceae Spermatophyta Viridiplantae

Human Protein / Gene in interaction

19 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q16637 Survival motor neuron protein Unclassified protein CHEMBL1586581 CHEMBL1613842 (1)
4 / 2
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein CHEMBL1586581 CHEMBL1738312 (1)
0 / 0
Q99700 Ataxin-2 Unclassified protein CHEMBL1586581 CHEMBL2114784 (1)
1 / 1
P02545 Prelamin-A/C Unclassified protein CHEMBL1586581 CHEMBL1614073 (1)
11 / 10
Q9NR56 Muscleblind-like protein 1 Unclassified protein CHEMBL1586581 CHEMBL1614166 (1)
1 / 0
P42858 Huntingtin Unclassified protein CHEMBL1586581 CHEMBL1613918 (1)
1 / 1
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein CHEMBL1586581 CHEMBL1794584 (1)
2 / 0
O75496 Geminin Unclassified protein CHEMBL1586581 CHEMBL2114843 (1) CHEMBL2114780 (1)
0 / 0
P51151 Ras-related protein Rab-9A Unclassified protein CHEMBL1586581 CHEMBL1613838 (1)
0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor CHEMBL1586581 CHEMBL2114788 (1)
0 / 0
O15118 Niemann-Pick C1 protein Unclassified protein CHEMBL1586581 CHEMBL1614342 (1)
1 / 1
O75030 Microphthalmia-associated transcription factor Unclassified protein CHEMBL1586581 CHEMBL1738671 (1) CHEMBL1737866 (1)
CHEMBL1738318 (1)
4 / 5
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein CHEMBL1586581 CHEMBL1738588 (1) CHEMBL1738317 (1)
0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein CHEMBL1586581 CHEMBL1738184 (1)
0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme CHEMBL1586581 CHEMBL2354311 (1)
1 / 0
Q8IUX4 DNA dC->dU-editing enzyme APOBEC-3F Enzyme CHEMBL1586581 CHEMBL1963966 (1)
0 / 0
Q00653 Nuclear factor NF-kappa-B p100 subunit Transcription Factor CHEMBL1586581 CHEMBL1613870 (1)
0 / 0
Q04206 Transcription factor p65 Transcription Factor CHEMBL1586581 CHEMBL1613870 (1)
0 / 0
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor CHEMBL1586581 CHEMBL1613870 (1)
0 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (26)

OMIM preferred title UniProt
#103470 Albinism, ocular, with sensorineural deafness O75030
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#114500 Colorectal cancer; crc P84022
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#137800 Glioma susceptibility 1; glm1 O75874
#610140 Heart-hand syndrome, slovenian type P02545
#143100 Huntington disease; hd P42858
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#614456 Melanoma, cutaneous malignant, susceptibility to, 8; cmm8 O75030
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#257220 Niemann-pick disease, type c1; npc1 O15118
#275210 Restrictive dermopathy, lethal P02545
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#103500 Tietz syndrome O75030
#193510 Waardenburg syndrome, type 2a; ws2a O75030

KEGG DISEASE (18)

KEGG disease name UniProt
H00136 Niemann-Pick disease type C (NPC) O15118 (related)
H00038 Malignant melanoma O75030 (related)
O75030 (marker)
H00169 Ocular albinism O75030 (related)
H00759 Waardenburg syndrome (WS) O75030 (related)
H01187 Tietz syndrome O75030 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00059 Huntington's disease (HD) P42858 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
Q16637 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)