Species

KNApSAcK Entry

Organism name Podocarpus nagai
Genus Podocarpus
Family Podocarpaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Nageia nagi
Linked NCBI taxonomy ID 36012
Linked level species

Family

Family in NCBI taxonomy Podocarpaceae
ID 3362

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Spermatophyta
ID 58024

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00006490 External link 512 Podocarpusflavone A
CHEMBL220745
C094150
2 / 1 / 2 No. 34 No. 18
C00000278 External link 512 Ponalactone A
No. 1155 No. 41
C00000270 External link 512 Nagilactone C
CHEMBL176006
CHEMBL487996
C004552
No. 1854 No. 41
C00000269 External link 512 Nagilactone B
CHEMBL1586581
19 / 26 / 18 No. 1854 No. 41
C00000268 External link 512 Nagilactone A
CHEMBL1381439
13 / 20 / 13 No. 1854 No. 41

Human Protein / Gene in interactions

24 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q16637 Survival motor neuron protein Unclassified protein C00000268 C00000269 4 / 1
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00000268 C00000269 1 / 0
Q99700 Ataxin-2 Unclassified protein C00000268 C00000269 1 / 1
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00000268 C00000269 0 / 0
P02545 Prelamin-A/C Unclassified protein C00000268 C00000269 11 / 10
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00000268 C00000269 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00000268 C00000269 0 / 0
P42858 Huntingtin Unclassified protein C00000268 C00000269 1 / 1
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00000268 C00000269 2 / 0
O75496 Geminin Unclassified protein C00000268 C00000269 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00000268 0 / 0
P43235 Cathepsin K C1A C00006490 1 / 2
P51151 Ras-related protein Rab-9A Unclassified protein C00000269 0 / 0
P56817 Beta-secretase 1 A1A C00006490 0 / 0
O15118 Niemann-Pick C1 protein Unclassified protein C00000269 1 / 1
O75030 Microphthalmia-associated transcription factor Unclassified protein C00000269 4 / 4
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00000269 1 / 0
Q9UNA4 DNA polymerase iota Enzyme C00000268 0 / 0
P06746 DNA polymerase beta Enzyme C00000268 0 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00000269 0 / 0
Q8IUX4 DNA dC->dU-editing enzyme APOBEC-3F Enzyme C00000269 0 / 0
Q00653 Nuclear factor NF-kappa-B p100 subunit Transcription Factor C00000269 0 / 0
Q04206 Transcription factor p65 Transcription Factor C00000269 0 / 0
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor C00000269 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (27)

OMIM preferred title UniProt
#103470 Albinism, ocular, with sensorineural deafness O75030
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#114500 Colorectal cancer; crc P84022
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#137800 Glioma susceptibility 1; glm1 O75874
#610140 Heart-hand syndrome, slovenian type P02545
#143100 Huntington disease; hd P42858
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#614456 Melanoma, cutaneous malignant, susceptibility to, 8; cmm8 O75030
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#257220 Niemann-pick disease, type c1; npc1 O15118
#265800 Pycnodysostosis P43235
#275210 Restrictive dermopathy, lethal P02545
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#103500 Tietz syndrome O75030
#193510 Waardenburg syndrome, type 2a; ws2a O75030

KEGG DISEASE (20)

KEGG name UniProt
H00136 Niemann-Pick disease type C (NPC) O15118 (related)
H00038 Malignant melanoma O75030 (related)
O75030 (marker)
H00169 Ocular albinism O75030 (related)
H00759 Waardenburg syndrome (WS) O75030 (related)
H01187 Tietz syndrome O75030 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00059 Huntington's disease (HD) P42858 (related)
H00273 Pycnodysostosis P43235 (related)
H00425 Lysosomal cysteine protease deficiencies P43235 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)