KNApSAcK Metabolite C00002845
Metabolite
KNApSAcK Entry
| id | C00002845 |
|---|---|
| Name | (1S,3R)-Nanaomycin A |
| CAS RN | 52934-83-5 |
| Standard InChI | InChI=1S/C16H14O6/c1-7-13-10(5-8(22-7)6-12(18)19)15(20)9-3-2-4-11(17)14(9)16(13)21/h2-4,7-8,17H,5-6H2,1H3,(H,18,19)/t7-,8+/m0/s1 |
| Standard InChI (Main Layer) | InChI=1S/C16H14O6/c1-7-13-10(5-8(22-7)6-12(18)19)15(20)9-3-2-4-11(17)14(9)16(13)21/h2-4,7-8,17H,5-6H2,1H3,(H,18,19) |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 1191 |
Link
ChEMBL
| By standard InChI | CHEMBL2106789 |
|---|---|
| By standard InChI Main Layer | CHEMBL1212972 CHEMBL2106789 |
KEGG
| By LinkDB | C10377 |
|---|
CTD
| By CAS RN | C008638 |
|---|
Species
Summary
Plant class
| class name | count |
|---|
Family
| family name | count |
|---|---|
| Streptomycetaceae | 1 |
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Streptomyces rosa var. notoensis | 1883 | Streptomycetaceae | Bacteria |
Human Protein / Gene in interaction
20 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| Q99700 | Ataxin-2 | Unclassified protein | CHEMBL1212972 |
CHEMBL2114784
(1)
|
1 / 1 |
| P37840 | Alpha-synuclein | Unclassified protein | CHEMBL1212972 |
CHEMBL2354282
(1)
|
4 / 2 |
| P11473 | Vitamin D3 receptor | NR1I1 | CHEMBL1212972 |
CHEMBL1794311
(1)
|
2 / 3 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | CHEMBL1212972 |
CHEMBL1794584
(1)
|
2 / 0 |
| O75496 | Geminin | Unclassified protein | CHEMBL1212972 |
CHEMBL2114843
(1)
CHEMBL2114780
(1)
|
0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | CHEMBL1212972 |
CHEMBL2114788
(1)
|
0 / 0 |
| P51684 | C-C chemokine receptor type 6 | CC chemokine receptor | CHEMBL1212972 |
CHEMBL1738164
(1)
|
0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | CHEMBL1212972 |
CHEMBL2114810
(1)
CHEMBL2114817
(1)
|
7 / 3 |
| Q9Y253 | DNA polymerase eta | Enzyme | CHEMBL1212972 |
CHEMBL1794569
(1)
|
1 / 1 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | CHEMBL1212972 |
CHEMBL1794401
(1)
|
0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | CHEMBL1212972 |
CHEMBL1794483
(1)
|
0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | CHEMBL1212972 |
CHEMBL1737991
(1)
|
0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | CHEMBL1212972 |
CHEMBL1738184
(1)
|
0 / 0 |
| P07900 | Heat shock protein HSP 90-alpha | Other cytosolic protein | CHEMBL1212972 |
CHEMBL1794333
(1)
|
0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | CHEMBL1212972 |
CHEMBL2354311
(1)
|
1 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | CHEMBL1212972 |
CHEMBL2114738
(1)
|
0 / 0 |
| Q9H0H5 | Rac GTPase-activating protein 1 | Unclassified protein | CHEMBL1212972 |
CHEMBL2114881
(1)
|
0 / 0 |
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | CHEMBL1212972 |
CHEMBL2114796
(1)
|
2 / 1 |
| Q06710 | Paired box protein Pax-8 | Unclassified protein | CHEMBL1212972 |
CHEMBL2354301
(1)
|
1 / 2 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | CHEMBL1212972 |
CHEMBL2354287
(1)
|
1 / 1 |
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (21)
| OMIM | preferred title | UniProt |
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #114500 | Colorectal cancer; crc |
P84022
Q14191 |
| #127750 | Dementia, lewy body; dlb |
P37840
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #218700 | Hypothyroidism, congenital, nongoitrous, 2; chng2 |
Q06710
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
| #605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
| #168600 | Parkinson disease, late-onset; pd |
P37840
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #277700 | Werner syndrome; wrn |
Q14191
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG DISEASE (14)
| KEGG | disease name | UniProt |
|---|---|---|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00057 | Parkinson's disease (PD) |
P37840
(related)
|
| H00066 | Lewy body dementia (LBD) |
P37840
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00032 | Thyroid cancer |
Q06710
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
Q06710
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
Q13148
(related)
|
| H00296 | Defects in RecQ helicases |
Q14191
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|