Species

KNApSAcK Entry

Organism name Streptomyces rosa var. notoensis
Genus Streptomyces
Family Streptomycetaceae
Kingdom Bacteria

NCBI taxonomy

Entry

Linked NCBI taxonomy name Streptomyces
Linked NCBI taxonomy ID 1883
Linked level genus

Family

Family in NCBI taxonomy Streptomycetaceae
ID 2062

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Bacteria
ID 2

Plant class

Plant class
ID

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00002845 External link 512 (1S,3R)-Nanaomycin A
CHEMBL1212972
CHEMBL2106789
C008638
20 / 21 / 14 No. 1191

Human Protein / Gene in interactions

20 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q99700 Ataxin-2 Unclassified protein C00002845 1 / 1
P37840 Alpha-synuclein Unclassified protein C00002845 4 / 2
P11473 Vitamin D3 receptor NR1I1 C00002845 2 / 3
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00002845 2 / 0
O75496 Geminin Unclassified protein C00002845 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00002845 0 / 0
P51684 C-C chemokine receptor type 6 CC chemokine receptor C00002845 0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00002845 7 / 3
Q9Y253 DNA polymerase eta Enzyme C00002845 1 / 1
P83916 Chromobox protein homolog 1 Unclassified protein C00002845 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00002845 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00002845 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00002845 0 / 0
P07900 Heat shock protein HSP 90-alpha Other cytosolic protein C00002845 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00002845 1 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00002845 0 / 0
Q9H0H5 Rac GTPase-activating protein 1 Unclassified protein C00002845 0 / 0
Q14191 Werner syndrome ATP-dependent helicase Enzyme C00002845 2 / 1
Q06710 Paired box protein Pax-8 Unclassified protein C00002845 1 / 2
Q13148 TAR DNA-binding protein 43 Unclassified protein C00002845 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (21)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#114500 Colorectal cancer; crc P84022
Q14191
#127750 Dementia, lewy body; dlb P37840
#137800 Glioma susceptibility 1; glm1 O75874
#218700 Hypothyroidism, congenital, nongoitrous, 2; chng2 Q06710
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#174800 Mccune-albright syndrome; mas P63092
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#166350 Osseous heteroplasia, progressive; poh P63092
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P37840
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#277700 Werner syndrome; wrn Q14191
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (14)

KEGG name UniProt
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00057 Parkinson's disease (PD) P37840 (related)
H00066 Lewy body dementia (LBD) P37840 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00032 Thyroid cancer Q06710 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) Q06710 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)
H00296 Defects in RecQ helicases Q14191 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)