PCIDB

KNApSAcK Metabolite C00002905

Metabolite

KNApSAcK Entry

id C00002905
Name epsilon-Viniferin / (-)-epsilon-Viniferin
CAS RN 62218-08-0
Standard InChI InChI=1S/C28H22O6/c29-20-7-2-16(3-8-20)1-4-18-11-24(33)15-25-26(18)27(19-12-22(31)14-23(32)13-19)28(34-25)17-5-9-21(30)10-6-17/h1-15,27-33H/b4-1+/t27-,28+/m1/s1
Standard InChI (Main Layer) InChI=1S/C28H22O6/c29-20-7-2-16(3-8-20)1-4-18-11-24(33)15-25-26(18)27(19-12-22(31)14-23(32)13-19)28(34-25)17-5-9-21(30)10-6-17/h1-15,27-33H

Cluster

Phytochemical cluster No. 30
KCF-S cluster No. 108

Link

ChEMBL

By standard InChI CHEMBL1224875
By standard InChI Main Layer CHEMBL498439 CHEMBL1224875 CHEMBL1224889

KEGG

By LinkDB C10289

CTD

By CAS RN C091891

Human Protein / Gene in interaction

CTD interaction (10)

compound gene gene name gene description interaction interaction type form reference
pmid
C091891 4363 ABCC1
ABC29
ABCC
GS-X
MRP
MRP1
ATP-binding cassette, sub-family C (CFTR/MRP), member 1 epsilon-viniferin inhibits the reaction [ABCC1 protein results in increased transport of 2',7'-bis-(carboxypropyl)-5(6)-carboxyfluorescein] decreases reaction
/ increases transport
protein 16827148
C091891 4363 ABCC1
ABC29
ABCC
GS-X
MRP
MRP1
ATP-binding cassette, sub-family C (CFTR/MRP), member 1 epsilon-viniferin results in decreased activity of ABCC1 protein decreases activity
protein 16827148
C091891 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) epsilon-viniferin results in decreased activity of CYP1A1 protein decreases activity
protein 12818727
C091891 1544 CYP1A2
CP12
P3-450
P450(PA)
cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) epsilon-viniferin results in decreased activity of CYP1A2 protein decreases activity
protein 12818727
C091891 1545 CYP1B1
CP1B
CYPIB1
GLC3A
P4501B1
cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) epsilon-viniferin results in decreased activity of CYP1B1 protein decreases activity
protein 12818727
C091891 1548 CYP2A6
CPA6
CYP2A
CYP2A3
CYPIIA6
P450C2A
P450PB
cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1) epsilon-viniferin results in decreased activity of CYP2A6 protein decreases activity
protein 12818727
C091891 1555 CYP2B6
CPB6
CYP2B
CYP2B7
CYP2B7P
CYPIIB6
EFVM
IIB1
P450
cytochrome P450, family 2, subfamily B, polypeptide 6 (EC:1.14.14.1) epsilon-viniferin results in decreased activity of CYP2B6 protein decreases activity
protein 12818727
C091891 1571 CYP2E1
CPE1
CYP2E
P450-J
P450C2E
cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) epsilon-viniferin results in decreased activity of CYP2E1 protein decreases activity
protein 12818727
C091891 1576 CYP3A4
CP33
CP34
CYP3A
CYP3A3
CYPIIIA3
CYPIIIA4
HLP
NF-25
P450C3
P450PCN1
cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) epsilon-viniferin results in decreased activity of CYP3A4 protein decreases activity
protein 12818727
C091891 3949 LDLR
FH
FHC
LDLCQ2
low density lipoprotein receptor epsilon-viniferin results in increased expression of LDLR mRNA increases expression
mRNA 22153697