PCIDB

KNApSAcK Metabolite C00032618

Metabolite

KNApSAcK Entry

id C00032618
Name 6-Hydroxysalicylic acid / 2,6-Dihydroxybenzoic acid
CAS RN 303-07-1
Standard InChI InChI=1S/C7H6O4/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3,8-9H,(H,10,11)
Standard InChI (Main Layer) InChI=1S/C7H6O4/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3,8-9H,(H,10,11)

Cluster

Phytochemical cluster No. 81
KCF-S cluster No. 817

Link

ChEMBL

By standard InChI CHEMBL454808
By standard InChI Main Layer CHEMBL454808

KEGG

By LinkDB

CTD

By CAS RN C412605

Species

Summary

Plant class

class name count
eudicotyledons 1

Family

family name count
Polygonaceae 1

List (1)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Polygonum cuspidatum 83819 Polygonaceae eudicotyledons Viridiplantae

Human Protein / Gene in interaction

12 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P09917 Arachidonate 5-lipoxygenase Oxidoreductase CHEMBL454808 CHEMBL1664429 (1)
0 / 0
P43166 Carbonic anhydrase 7 Lyase CHEMBL454808 CHEMBL2340802 (1)
0 / 0
P22894 Neutrophil collagenase M10A CHEMBL454808 CHEMBL1664434 (1)
0 / 0
P14780 Matrix metalloproteinase-9 M10A CHEMBL454808 CHEMBL1664435 (1)
2 / 2
P00918 Carbonic anhydrase 2 Lyase CHEMBL454808 CHEMBL2340803 (1)
1 / 2
Q9ULX7 Carbonic anhydrase 14 Lyase CHEMBL454808 CHEMBL2340799 (1)
0 / 0
O43570 Carbonic anhydrase 12 Lyase CHEMBL454808 CHEMBL2340800 (1)
1 / 2
P00915 Carbonic anhydrase 1 Lyase CHEMBL454808 CHEMBL2340804 (1)
0 / 0
P03956 Interstitial collagenase M10A CHEMBL454808 CHEMBL1664431 (1)
0 / 1
Q16790 Carbonic anhydrase 9 Lyase CHEMBL454808 CHEMBL2340801 (1)
0 / 1
P08253 72 kDa type IV collagenase M10A CHEMBL454808 CHEMBL1664432 (1)
1 / 3
P08254 Stromelysin-1 M10A CHEMBL454808 CHEMBL1664433 (1)
1 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (6)

OMIM preferred title UniProt
#614466 Coronary heart disease, susceptibility to, 6; chds6 P08254
#143860 Hyperchlorhidrosis, isolated O43570
#603932 Intervertebral disc disease; idd P14780
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#259600 Multicentric osteolysis, nodulosis, and arthropathy; mona P08253
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918

KEGG DISEASE (8)

KEGG disease name UniProt
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
Q16790 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00028 Choriocarcinoma P03956 (related)
P08253 (related)
H00025 Penile cancer P08253 (related)
P14780 (related)
H00472 Torg-Winchester syndrome P08253 (related)
H00479 Metaphyseal dysplasias P14780 (related)