PCIDB

KNApSAcK Metabolite C00036011

Metabolite

KNApSAcK Entry

id C00036011
Name 4',5,7-Trimethoxyisoflavone
CAS RN 1162-82-9
Standard InChI InChI=1S/C18H16O5/c1-20-12-6-4-11(5-7-12)14-10-23-16-9-13(21-2)8-15(22-3)17(16)18(14)19/h4-10H,1-3H3
Standard InChI (Main Layer) InChI=1S/C18H16O5/c1-20-12-6-4-11(5-7-12)14-10-23-16-9-13(21-2)8-15(22-3)17(16)18(14)19/h4-10H,1-3H3

Cluster

Phytochemical cluster No. 15
KCF-S cluster No. 35

Link

ChEMBL

By standard InChI CHEMBL13097
By standard InChI Main Layer CHEMBL13097

KEGG

By LinkDB

CTD

By CAS RN

Species

Summary

Plant class

class name count
rosids 1

Family

family name count
Ochnaceae 1

List (1)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Ochna afzelii 56628 Ochnaceae rosids Viridiplantae

Human Protein / Gene in interaction

10 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P37840 Alpha-synuclein Unclassified protein CHEMBL13097 CHEMBL2354282 (1)
4 / 2
P00352 Retinal dehydrogenase 1 Enzyme CHEMBL13097 CHEMBL1614458 (1)
0 / 0
O75496 Geminin Unclassified protein CHEMBL13097 CHEMBL2114780 (1)
0 / 0
P51151 Ras-related protein Rab-9A Unclassified protein CHEMBL13097 CHEMBL1613838 (1)
0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme CHEMBL13097 CHEMBL1613910 (1)
3 / 3
O15118 Niemann-Pick C1 protein Unclassified protein CHEMBL13097 CHEMBL1614342 (1)
1 / 1
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein CHEMBL13097 CHEMBL1738588 (1) CHEMBL1738317 (1)
0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL13097 CHEMBL1614108 (1) CHEMBL1613886 (1)
0 / 1
B2RXH2 Lysine-specific demethylase 4E Enzyme CHEMBL13097 CHEMBL1613914 (1)
0 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein CHEMBL13097 CHEMBL2354287 (1)
1 / 1

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (9)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#127750 Dementia, lewy body; dlb P37840
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#257220 Niemann-pick disease, type c1; npc1 O15118
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P37840

KEGG DISEASE (8)

KEGG disease name UniProt
H00136 Niemann-Pick disease type C (NPC) O15118 (related)
H00036 Osteosarcoma P08684 (marker)
H00057 Parkinson's disease (PD) P37840 (related)
H00066 Lewy body dementia (LBD) P37840 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)