Species

KNApSAcK Entry

Organism name Ochna afzelii
Genus Ochna
Family Ochnaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Ochna
Linked NCBI taxonomy ID 56628
Linked level genus

Family

Family in NCBI taxonomy Ochnaceae
ID 56627

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (11)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00009468 External link 512 Irisolone methyl ether
/ 5,4'-Dimethoxy-6,7-methylenedioxyisoflavone
/ 4',5-Dimethoxy-6,7-methylenedioxyisoflavone
No. 27 No. 15
C00036011 External link 512 4',5,7-Trimethoxyisoflavone
CHEMBL13097
10 / 9 / 8 No. 35 No. 15
C00036030 External link 512 Afzelone A
No. 57 No. 18
C00036031 External link 512 Afzelone B
No. 57 No. 18
C00006554 External link 512 Lophirone C
No. 375
C00014527 External link 512 Dihydrolophirone C
No. 375
C00019038 External link 512 Breynioside A
/ Lanceoloside A
No. 532
C00006551 External link 512 Calodenin B
No. 1251
C00006553 External link 512 Calodenin A
No. 1251
C00014526 External link 512 Isolophirone C
No. 1251
C00014705 External link 512 Afzelone D
/ Lophirone A dimethyl ether
No. 2947

Human Protein / Gene in interactions

10 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P37840 Alpha-synuclein Unclassified protein C00036011 4 / 2
P00352 Retinal dehydrogenase 1 Enzyme C00036011 0 / 0
O75496 Geminin Unclassified protein C00036011 0 / 0
P51151 Ras-related protein Rab-9A Unclassified protein C00036011 0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00036011 3 / 3
O15118 Niemann-Pick C1 protein Unclassified protein C00036011 1 / 1
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00036011 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00036011 0 / 1
B2RXH2 Lysine-specific demethylase 4E Enzyme C00036011 0 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein C00036011 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (9)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#127750 Dementia, lewy body; dlb P37840
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#257220 Niemann-pick disease, type c1; npc1 O15118
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P37840

KEGG DISEASE (8)

KEGG name UniProt
H00136 Niemann-Pick disease type C (NPC) O15118 (related)
H00036 Osteosarcoma P08684 (marker)
H00057 Parkinson's disease (PD) P37840 (related)
H00066 Lewy body dementia (LBD) P37840 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)