PCIDB

KNApSAcK Metabolite C00036480

Metabolite

KNApSAcK Entry

id C00036480
Name Colosic acid / 2alpha-Hydroxyursolic acid
CAS RN 4547-24-4
Standard InChI InChI=1S/C30H48O4/c1-17-10-13-30(25(33)34)15-14-28(6)19(23(30)18(17)2)8-9-22-27(5)16-20(31)24(32)26(3,4)21(27)11-12-29(22,28)7/h8,17-18,20-24,31-32H,9-16H2,1-7H3,(H,33,34)/t17-,18+,20-,21+,22-,23+,24+,27+,28-,29-,30+/m1/s1
Standard InChI (Main Layer) InChI=1S/C30H48O4/c1-17-10-13-30(25(33)34)15-14-28(6)19(23(30)18(17)2)8-9-22-27(5)16-20(31)24(32)26(3,4)21(27)11-12-29(22,28)7/h8,17-18,20-24,31-32H,9-16H2,1-7H3,(H,33,34)

Cluster

Phytochemical cluster No. 51
KCF-S cluster No. 13

Link

ChEMBL

By standard InChI CHEMBL391533
By standard InChI Main Layer CHEMBL391533 CHEMBL237535 CHEMBL391534 CHEMBL574993

KEGG

By LinkDB

CTD

By CAS RN C113861

Human Protein / Gene in interaction

17 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P11217 Glycogen phosphorylase, muscle form Enzyme CHEMBL391533 CHEMBL881513 (1)
1 / 1
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr CHEMBL391533 CHEMBL963010 (1) CHEMBL2089751 (1)
0 / 0
Q99700 Ataxin-2 Unclassified protein CHEMBL391533 CHEMBL2114784 (1)
1 / 1
P06746 DNA polymerase beta Enzyme CHEMBL391533 CHEMBL1002742 (1)
0 / 0
P10586 Receptor-type tyrosine-protein phosphatase F Receptor tyrosine-protein phosphatase CHEMBL391533 CHEMBL963013 (1)
0 / 0
P28845 Corticosteroid 11-beta-dehydrogenase isozyme 1 Enzyme CHEMBL391533 CHEMBL1072762 (2)
1 / 1
P42858 Huntingtin Unclassified protein CHEMBL391533 CHEMBL1613918 (1)
1 / 1
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein CHEMBL391533 CHEMBL1794584 (1)
2 / 0
O75496 Geminin Unclassified protein CHEMBL391533 CHEMBL2114843 (1)
0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein CHEMBL391533 CHEMBL1794401 (1)
0 / 0
P18433 Receptor-type tyrosine-protein phosphatase alpha Receptor tyrosine-protein phosphatase CHEMBL391533 CHEMBL963014 (1)
0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein CHEMBL391533 CHEMBL1738588 (1) CHEMBL1738317 (1)
0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein CHEMBL391533 CHEMBL1738184 (1)
0 / 0
P17706 Tyrosine-protein phosphatase non-receptor type 2 Tyr CHEMBL391533 CHEMBL963011 (1)
0 / 1
P29350 Tyrosine-protein phosphatase non-receptor type 6 Tyr CHEMBL391533 CHEMBL963012 (1)
0 / 0
P80365 Corticosteroid 11-beta-dehydrogenase isozyme 2 Enzyme CHEMBL391533 CHEMBL1072763 (1)
1 / 1
P23469 Receptor-type tyrosine-protein phosphatase epsilon Receptor tyrosine-protein phosphatase CHEMBL391533 CHEMBL963015 (1)
0 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (7)

OMIM preferred title UniProt
#218030 Apparent mineralocorticoid excess; ame P80365
#114500 Colorectal cancer; crc P84022
#604931 Cortisone reductase deficiency 1; cortrd1 P28845
#232600 Glycogen storage disease v P11217
#143100 Huntington disease; hd P42858
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#183090 Spinocerebellar ataxia 2; sca2 Q99700

KEGG DISEASE (6)

KEGG disease name UniProt
H00069 Glycogen storage diseases (GSD) P11217 (related)
H00408 Type I diabetes mellitus P17706 (related)
H01111 Cortisone reductase deficiency (CRD) P28845 (related)
H00059 Huntington's disease (HD) P42858 (related)
H00259 Apparent mineralocorticoid excess syndrome P80365 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)