PCIDB

KNApSAcK Metabolite C00003838

Metabolite

KNApSAcK Entry

id C00003838
Name Pectolinarigenin
CAS RN 520-12-7
Standard InChI InChI=1S/C17H14O6/c1-21-10-5-3-9(4-6-10)13-7-11(18)15-14(23-13)8-12(19)17(22-2)16(15)20/h3-8,19-20H,1-2H3
Standard InChI (Main Layer) InChI=1S/C17H14O6/c1-21-10-5-3-9(4-6-10)13-7-11(18)15-14(23-13)8-12(19)17(22-2)16(15)20/h3-8,19-20H,1-2H3

Cluster

Phytochemical cluster No. 15
KCF-S cluster No. 3

Link

ChEMBL

By standard InChI CHEMBL78010
By standard InChI Main Layer CHEMBL78010

KEGG

By LinkDB C17784

CTD

By CAS RN C079207

Human Protein / Gene in interaction

31 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q99700 Ataxin-2 Unclassified protein CHEMBL78010 CHEMBL2114784 (1)
1 / 1
P06746 DNA polymerase beta Enzyme CHEMBL78010 CHEMBL1614079 (1)
0 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme CHEMBL78010 CHEMBL1794585 (1)
0 / 0
O75496 Geminin Unclassified protein CHEMBL78010 CHEMBL2114780 (1)
0 / 0
P51151 Ras-related protein Rab-9A Unclassified protein CHEMBL78010 CHEMBL1613838 (1)
0 / 0
P38398 Breast cancer type 1 susceptibility protein Enzyme CHEMBL78010 CHEMBL2114807 (1)
4 / 2
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein CHEMBL78010 CHEMBL2114817 (1)
7 / 3
O15118 Niemann-Pick C1 protein Unclassified protein CHEMBL78010 CHEMBL1614342 (1)
1 / 1
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein CHEMBL78010 CHEMBL1738588 (1) CHEMBL1738317 (1)
0 / 0
P10636 Microtubule-associated protein tau Unclassified protein CHEMBL78010 CHEMBL1614421 (1)
4 / 3
O00255 Menin Unclassified protein CHEMBL78010 CHEMBL1614257 (1)
2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme CHEMBL78010 CHEMBL1614257 (1)
1 / 3
Q00653 Nuclear factor NF-kappa-B p100 subunit Transcription Factor CHEMBL78010 CHEMBL1613870 (1)
0 / 0
Q04206 Transcription factor p65 Transcription Factor CHEMBL78010 CHEMBL1613870 (1)
0 / 0
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor CHEMBL78010 CHEMBL1613870 (1)
0 / 0
Q13748 Tubulin alpha-3C/D chain Structural CHEMBL78010 CHEMBL818984 (1) CHEMBL820476 (1)
0 / 0
P68366 Tubulin alpha-4A chain Structural CHEMBL78010 CHEMBL818984 (1) CHEMBL820476 (1)
0 / 0
Q9H4B7 Tubulin beta-1 chain Structural CHEMBL78010 CHEMBL818984 (1) CHEMBL820476 (1)
1 / 0
P04350 Tubulin beta-4A chain Structural CHEMBL78010 CHEMBL818984 (1) CHEMBL820476 (1)
2 / 0
Q3ZCM7 Tubulin beta-8 chain Structural CHEMBL78010 CHEMBL818984 (1) CHEMBL820476 (1)
0 / 0
P07437 Tubulin beta chain Structural CHEMBL78010 CHEMBL818984 (1) CHEMBL820476 (1)
0 / 0
Q71U36 Tubulin alpha-1A chain Structural CHEMBL78010 CHEMBL818984 (1) CHEMBL820476 (1)
1 / 1
P68371 Tubulin beta-4B chain Structural CHEMBL78010 CHEMBL818984 (1) CHEMBL820476 (1)
0 / 0
Q13509 Tubulin beta-3 chain Structural CHEMBL78010 CHEMBL818984 (1) CHEMBL820476 (1)
2 / 1
O94925 Glutaminase kidney isoform, mitochondrial Enzyme CHEMBL78010 CHEMBL2114738 (1)
0 / 0
P68363 Tubulin alpha-1B chain Unclassified protein CHEMBL78010 CHEMBL818984 (1) CHEMBL820476 (1)
0 / 0
Q13885 Tubulin beta-2A chain Structural CHEMBL78010 CHEMBL818984 (1) CHEMBL820476 (1)
0 / 0
Q6PEY2 Tubulin alpha-3E chain Unclassified protein CHEMBL78010 CHEMBL818984 (1) CHEMBL820476 (1)
0 / 0
Q9BQE3 Tubulin alpha-1C chain Unclassified protein CHEMBL78010 CHEMBL818984 (1) CHEMBL820476 (1)
0 / 0
Q9BUF5 Tubulin beta-6 chain Structural CHEMBL78010 CHEMBL818984 (1) CHEMBL820476 (1)
0 / 0
Q9BVA1 Tubulin beta-2B chain Structural CHEMBL78010 CHEMBL818984 (1) CHEMBL820476 (1)
1 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (27)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#114480 Breast cancer P38398
#604370 Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 P38398
#614039 Cortical dysplasia, complex, with other brain malformations 1; cdcbm1 Q13509
#128101 Dystonia 4, torsion, autosomal dominant; dyt4 P04350
#600638 Fibrosis of extraocular muscles, congenital, 3a, with or without extraocular involvement; cfeom3a Q13509
#600274 Frontotemporal dementia; ftd P10636
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#612438 Leukodystrophy, hypomyelinating, 6; hld6 P04350
#611603 Lissencephaly 3; lis3 Q71U36
#613112 Macrothrombocytopenia, autosomal dominant, tubb1-related Q9H4B7
#174800 Mccune-albright syndrome; mas P63092
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#257220 Niemann-pick disease, type c1; npc1 O15118
#166350 Osseous heteroplasia, progressive; poh P63092
#167000 Ovarian cancer P38398
#614320 Pancreatic cancer, susceptibility to, 4; pnca4 P38398
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#102200 Pituitary adenoma, growth hormone-secreting P63092
#610031 Polymicrogyria, symmetric or asymmetric; pmgysa Q9BVA1
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (19)

KEGG disease name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00136 Niemann-Pick disease type C (NPC) O15118 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00027 Ovarian cancer P38398 (related)
H00031 Breast cancer P38398 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00838 Congenital fibrosis of the extraocular muscles (CFEOM) Q13509 (related)
H00268 Lissencephaly (LIS) Q71U36 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)