PCIDB

KNApSAcK Metabolite C00042067

Metabolite

KNApSAcK Entry

id C00042067
Name 2,5-Dideoxy-2,5-imino-D-glucitol / (+)-2,5-Dideoxy-2,5-imino-D-glucitol
CAS RN 132295-44-4
Standard InChI InChI=1S/C6H13NO4/c8-1-3-5(10)6(11)4(2-9)7-3/h3-11H,1-2H2/t3-,4+,5-,6-/m1/s1
Standard InChI (Main Layer) InChI=1S/C6H13NO4/c8-1-3-5(10)6(11)4(2-9)7-3/h3-11H,1-2H2

Cluster

Phytochemical cluster
KCF-S cluster No. 667

Link

ChEMBL

By standard InChI CHEMBL259905
By standard InChI Main Layer CHEMBL10437 CHEMBL312653 CHEMBL121093 CHEMBL259905 CHEMBL405957 CHEMBL469844 CHEMBL2008021

KEGG

By LinkDB

CTD

By CAS RN

Species

Summary

Plant class

class name count
Liliopsida 1

Family

family name count
Stemonaceae 1

List (1)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Stemona tuberosa 167572 Stemonaceae Liliopsida Viridiplantae

Human Protein / Gene in interaction

8 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P04062 Glucosylceramidase Enzyme CHEMBL10437 CHEMBL650036 (1) CHEMBL650038 (1)
6 / 4
Q14697 Neutral alpha-glucosidase AB Enzyme CHEMBL121093 CHEMBL641728 (1) CHEMBL645811 (1)
CHEMBL645965 (1) CHEMBL645968 (1)
CHEMBL646086 (1)
0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase CHEMBL259905 CHEMBL1007693 (1)
1 / 1
Q9H227 Cytosolic beta-glucosidase Enzyme CHEMBL259905 CHEMBL1007694 (1)
0 / 0
P35573 Glycogen debranching enzyme Enzyme CHEMBL312653 CHEMBL259905 CHEMBL405957 CHEMBL923883 (3)
1 / 1
P04066 Tissue alpha-L-fucosidase Enzyme CHEMBL121093 CHEMBL649571 (1) CHEMBL649586 (1)
1 / 2
P06280 Alpha-galactosidase A Enzyme CHEMBL469844 CHEMBL1168041 (1) CHEMBL1168060 (1)
CHEMBL1168063 (1) CHEMBL1168064 (1)
CHEMBL1168065 (1) CHEMBL1168066 (1)
1 / 1
O43451 Maltase-glucoamylase, intestinal Hydrolase CHEMBL312653 CHEMBL710107 (1)
0 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (10)

OMIM preferred title UniProt
#301500 Fabry disease P06280
#230000 Fucosidosis P04066
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#232300 Glycogen storage disease ii P10253
#232400 Glycogen storage disease iii P35573
#168600 Parkinson disease, late-onset; pd P04062

KEGG DISEASE (8)

KEGG disease name UniProt
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00141 Fucosidosis P04066 (related)
H00422 Glycoproteinoses P04066 (related)
H00125 Fabry disease P06280 (related)
H00069 Glycogen storage diseases (GSD) P10253 (related)
P35573 (related)