Species

KNApSAcK Entry

Organism name Stemona tuberosa
Genus Stemona
Family Stemonaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Stemona tuberosa
Linked NCBI taxonomy ID 167572
Linked level species

Family

Family in NCBI taxonomy Stemonaceae
ID 49662

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Liliopsida
ID 4447

Metabolite list (39)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00041896 External link 512 Stilbostemin H 3'-beta-D-glucopyranoside
/ (-)-Stilbostemin H 3'-beta-D-glucopyranoside
CHEMBL495844
No. 36 No. 13
C00041895 External link 512 Stilbostemin B 3'-beta-D-glucopyranoside
/ (-)-Stilbostemin B 3'-beta-D-glucopyranoside
CHEMBL495642
No. 36 No. 13
C00034284 External link 512 Stemanthrene A
CHEMBL480658
No. 75 No. 28
C00034285 External link 512 Stemanthrene B
CHEMBL480659
No. 75 No. 28
C00034286 External link 512 Stemanthrene C
CHEMBL480660
No. 75 No. 28
C00034287 External link 512 Stemanthrene D
CHEMBL444939
No. 75 No. 28
C00042067 External link 512 2,5-Dideoxy-2,5-imino-D-glucitol
/ (+)-2,5-Dideoxy-2,5-imino-D-glucitol
CHEMBL10437
CHEMBL312653
CHEMBL121093
CHEMBL259905
CHEMBL405957
CHEMBL469844
CHEMBL2008021
8 / 10 / 8 No. 667
C00042220 External link 512 alpha-Homonojirimycin
/ (+)-alpha-Homonojirimycin
CHEMBL87169
CHEMBL320116
CHEMBL327137
CHEMBL501355
CHEMBL1169500
CHEMBL2093079
CHEMBL2093897
CHEMBL2111688
CHEMBL2114210
CHEMBL2115215
C106502
6 / 9 / 8 No. 667
C00029158 External link 512 Tuberostemonone
No. 733
C00028739 External link 512 N-Oxytuberostemonine
No. 733
C00026716 External link 512 Tuberostemonine H
/ (+)-Tuberostemonine H
/ (9alpha)-Neotuberostemonine
CHEMBL517375
CHEMBL479493
CHEMBL1317235
2 / 4 / 3 No. 733
C00041952 External link 512 Tuberostemonine K
/ (-)-Tuberostemonine K
CHEMBL517375
CHEMBL479493
CHEMBL1317235
2 / 4 / 3 No. 733
C00034732 External link 512 Tuberostemonine
/ (-)-Tuberostemonine
CHEMBL517375
CHEMBL479493
CHEMBL1317235
C034243
2 / 4 / 3 No. 733
C00029153 External link 512 Tuberostemonine A
CHEMBL517375
CHEMBL479493
CHEMBL1317235
2 / 4 / 3 No. 733
C00028678 External link 512 Stemonine LG
/ Neotuberostemonine
/ Tuberostemonine LG
CHEMBL517375
CHEMBL479493
CHEMBL1317235
2 / 4 / 3 No. 733
C00029156 External link 512 Tuberostemoninol
No. 733
C00026715 External link 512 Tuberostemonine J
/ (+)-Tuberostemonine J
/ (9alpa,9aalpha)-Neotuberostemonin
CHEMBL517375
CHEMBL479493
CHEMBL1317235
2 / 4 / 3 No. 733
C00028104 External link 512 Croomine
/ (+)-Croomine
C082845
No. 1204
C00041951 External link 512 Tuberospironine
No. 1204
C00029050 External link 512 Stemotinine
No. 1204
C00029048 External link 512 Stemonine
/ (-)-Stemonine
No. 1204
C00034428 External link 512 6-Hydroxycroomine
/ 6alpha-Hydroxycroomine
No. 1204
C00028416 External link 512 Isostemotinine
No. 1204
C00034774 External link 512 6alpha-Hydroxycroomine
/ (+)-6.alpha.-Hydroxycroomine
No. 1204
C00034283 External link 512 Stemanthraquinone
No. 2619
C00029051 External link 512 Stenine
/ (-)-Stenine
No. 2649
C00026717 External link 512 Neostenine
/ Isostenine
/ (+)-Neostenine
No. 2649
C00040388 External link 512 Stemoenonine
/ (+)-Stemoenonine
CHEMBL521126
No. 3024
C00039914 External link 512 Oxystemoenonine
/ (-)-Oxystemoenonine
No. 3024
C00038115 External link 512 1,9a-seco-Stemoenonine
/ (-)-1,9a-seco-Stemoenonine
No. 3024
C00038338 External link 512 9a-O-Methylstemoenonine
/ (-)-9a-O-Methylstemoenonine
CHEMBL482671
No. 3024
C00028785 External link 512 Oxotuberostemonine
No. 3354
C00026810 External link 512 Neotuberostemonol
No. 3354
C00029157 External link 512 Tuberostemonol
No. 3354
C00029159 External link 512 Tuberostemospironine
/ (-)-Tuberostemospironine
No. 3540
C00029044 External link 512 Stemoamide
/ (-)-Stemoamide
No. 3540
C00028182 External link 512 Didehydrotuberostemonine
No. 4086
C00026718 External link 512 epi-Bisdehydroneotuberostemonine J
/ (-)-epi-Bisdehydroneotuberostemonine J
No. 4086
C00029152 External link 512 Tuberostemoamide
CHEMBL482672
No. 7942

Human Protein / Gene in interactions

11 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00026715 C00026716 C00028678 C00029153 C00034732 C00041952 1 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00026715 C00026716 C00028678 C00029153 C00034732 C00041952 3 / 3
P10253 Lysosomal alpha-glucosidase Hydrolase C00042067 C00042220 1 / 1
P04062 Glucosylceramidase Enzyme C00042067 C00042220 6 / 4
P06280 Alpha-galactosidase A Enzyme C00042067 C00042220 1 / 1
P04066 Tissue alpha-L-fucosidase Enzyme C00042067 C00042220 1 / 2
O43451 Maltase-glucoamylase, intestinal Hydrolase C00042067 C00042220 0 / 0
Q8TET4 Neutral alpha-glucosidase C Enzyme C00042220 0 / 0
Q9H227 Cytosolic beta-glucosidase Enzyme C00042067 0 / 0
Q14697 Neutral alpha-glucosidase AB Enzyme C00042067 0 / 0
P35573 Glycogen debranching enzyme Enzyme C00042067 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (14)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#608902 Drug metabolism, poor, cyp2d6-related P10635
#301500 Fabry disease P06280
#230000 Fucosidosis P04066
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#232300 Glycogen storage disease ii P10253
#232400 Glycogen storage disease iii P35573
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#168600 Parkinson disease, late-onset; pd P04062

KEGG DISEASE (11)

KEGG name UniProt
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00141 Fucosidosis P04066 (related)
H00422 Glycoproteinoses P04066 (related)
H00125 Fabry disease P06280 (related)
H00069 Glycogen storage diseases (GSD) P10253 (related)
P35573 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)