KNApSAcK Metabolite C00043271
Metabolite
KNApSAcK Entry
| id | C00043271 |
|---|---|
| Name | Anthraquinone |
| CAS RN | 84-65-1 |
| Standard InChI | InChI=1S/C14H8O2/c15-13-9-5-1-2-6-10(9)14(16)12-8-4-3-7-11(12)13/h1-8H |
| Standard InChI (Main Layer) | InChI=1S/C14H8O2/c15-13-9-5-1-2-6-10(9)14(16)12-8-4-3-7-11(12)13/h1-8H |
Cluster
| Phytochemical cluster | No. 62 |
|---|---|
| KCF-S cluster | No. 41 |
Link
ChEMBL
| By standard InChI | CHEMBL55659 |
|---|---|
| By standard InChI Main Layer | CHEMBL55659 |
KEGG
| By LinkDB | C16207 |
|---|
CTD
| By CAS RN | C042834 |
|---|
Species
Summary
Plant class
| class name | count |
|---|
Family
| family name | count |
|---|---|
| Streptomycetaceae | 1 |
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Streptomyces sp. MST77755 | 1883 | Streptomycetaceae | Bacteria |
Human Protein / Gene in interaction
9 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| P19793 | Retinoic acid receptor RXR-alpha | NR2B1 | CHEMBL55659 |
CHEMBL1794371
(1)
|
0 / 0 |
| Q9HAW9 | UDP-glucuronosyltransferase 1-8 | Enzyme | CHEMBL55659 |
CHEMBL1743329
(1)
|
0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | CHEMBL55659 |
CHEMBL708330
(1)
CHEMBL708331
(1)
CHEMBL708332 (1) CHEMBL1794542 (1) |
1 / 1 |
| P30305 | M-phase inducer phosphatase 2 | Ser_Thr_Tyr | CHEMBL55659 |
CHEMBL965759
(1)
|
0 / 0 |
| P22309 | UDP-glucuronosyltransferase 1-1 | Enzyme | CHEMBL55659 |
CHEMBL1908080
(1)
|
5 / 1 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | CHEMBL55659 |
CHEMBL2114890
(1)
|
0 / 0 |
| O00255 | Menin | Unclassified protein | CHEMBL55659 |
CHEMBL1614531
(1)
|
2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | CHEMBL55659 |
CHEMBL1614531
(1)
|
1 / 3 |
| Q92731 | Estrogen receptor beta | NR3A2 | CHEMBL55659 |
CHEMBL708330
(1)
CHEMBL708331
(1)
CHEMBL708332 (1) |
0 / 1 |
CTD interaction (1)
| compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
|---|---|---|---|---|---|---|---|
| C042834 | 6352 |
CCL5
D17S136E RANTES SCYA5 SIS-delta SISd TCP228 eoCP |
chemokine (C-C motif) ligand 5 | 9,10-anthraquinone results in increased expression of CCL5 mRNA |
increases expression
|
mRNA |
23333790
|
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (9)
| OMIM | preferred title | UniProt |
|---|---|---|
| #601816 | Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 |
P22309
|
| #218800 | Crigler-najjar syndrome, type i |
P22309
|
| #606785 | Crigler-najjar syndrome, type ii |
P22309
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #143500 | Gilbert syndrome |
P22309
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #237900 | Hyperbilirubinemia, transient familial neonatal; hblrtfn |
P22309
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
KEGG DISEASE (9)
| KEGG | disease name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
Q92731 (marker) |
| H00208 | Hyperbilirubinemia |
P22309
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|