PCIDB

KNApSAcK Metabolite C00050256

Metabolite

KNApSAcK Entry

id C00050256
Name Thunberginol B
CAS RN 147666-81-7
Standard InChI InChI=1S/C15H10O6/c16-9-3-8-5-13(7-1-2-10(17)11(18)4-7)21-15(20)14(8)12(19)6-9/h1-6,16-19H
Standard InChI (Main Layer) InChI=1S/C15H10O6/c16-9-3-8-5-13(7-1-2-10(17)11(18)4-7)21-15(20)14(8)12(19)6-9/h1-6,16-19H

Cluster

Phytochemical cluster No. 17
KCF-S cluster No. 54

Link

ChEMBL

By standard InChI CHEMBL70501
By standard InChI Main Layer CHEMBL70501

KEGG

By LinkDB

CTD

By CAS RN C079056

Species

Summary

Plant class

class name count
asterids 1

Family

family name count
Hydrangeaceae 1

List (1)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Hydrangea macrophylla var. thunbergii 23109 Hydrangeaceae asterids Viridiplantae

Human Protein / Gene in interaction

20 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P04637 Cellular tumor antigen p53 Transcription Factor CHEMBL70501 CHEMBL1738132 (1) CHEMBL2114753 (1)
7 / 44
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme CHEMBL70501 CHEMBL1794585 (1)
0 / 0
P39748 Flap endonuclease 1 Enzyme CHEMBL70501 CHEMBL1794486 (1)
0 / 0
O75496 Geminin Unclassified protein CHEMBL70501 CHEMBL2114843 (1)
0 / 0
Q9Y253 DNA polymerase eta Enzyme CHEMBL70501 CHEMBL1794569 (1)
1 / 1
P09923 Intestinal-type alkaline phosphatase Enzyme CHEMBL70501 CHEMBL1738087 (1) CHEMBL1738192 (1)
0 / 0
P05186 Alkaline phosphatase, tissue-nonspecific isozyme Enzyme CHEMBL70501 CHEMBL1738668 (1)
3 / 1
Q9Y468 Lethal(3)malignant brain tumor-like protein 1 Unclassified protein CHEMBL70501 CHEMBL1614280 (1)
0 / 0
P11308 Transcriptional regulator ERG Unclassified protein CHEMBL70501 CHEMBL2114924 (1)
1 / 2
P11021 78 kDa glucose-regulated protein Unclassified protein CHEMBL70501 CHEMBL1963893 (1)
0 / 0
P51843 Nuclear receptor subfamily 0 group B member 1 Nuclear hormone receptor subfamily 0 group B member 1 CHEMBL70501 CHEMBL1794556 (1)
2 / 2
P10696 Alkaline phosphatase, placental-like Enzyme CHEMBL70501 CHEMBL1738185 (1)
0 / 1
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein CHEMBL70501 CHEMBL1738588 (1) CHEMBL1738317 (1)
0 / 0
Q9UNA4 DNA polymerase iota Enzyme CHEMBL70501 CHEMBL1794483 (1)
0 / 0
O75164 Lysine-specific demethylase 4A Enzyme CHEMBL70501 CHEMBL1737991 (1)
0 / 0
Q9UBT6 DNA polymerase kappa Enzyme CHEMBL70501 CHEMBL1794536 (1)
0 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme CHEMBL70501 CHEMBL2114738 (1)
0 / 0
Q9H0H5 Rac GTPase-activating protein 1 Unclassified protein CHEMBL70501 CHEMBL2114881 (1)
0 / 0
Q14191 Werner syndrome ATP-dependent helicase Enzyme CHEMBL70501 CHEMBL2114796 (1)
2 / 1
Q9HCT0 Fibroblast growth factor 22 Unclassified protein CHEMBL70501 CHEMBL2354256 (1)
0 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (16)

OMIM preferred title UniProt
#300018 46,xy sex reversal 2; srxy2 P51843
#300200 Adrenal hypoplasia, congenital; ahc P51843
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#114500 Colorectal cancer; crc Q14191
#133239 Esophageal cancer P04637
#612219 Ewing sarcoma; es P11308
#146300 Hypophosphatasia, adult P05186
#241510 Hypophosphatasia, childhood P05186
#241500 Hypophosphatasia, infantile P05186
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#211980 Lung cancer P04637
#260500 Papilloma of choroid plexus; cpp P04637
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
#277700 Werner syndrome; wrn Q14191
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (45)

KEGG disease name UniProt
H00004 Chronic myeloid leukemia (CML) P04637 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00016 Oral cancer P04637 (related)
P04637 (marker)
H00017 Esophageal cancer P04637 (related)
P04637 (marker)
H00018 Gastric cancer P04637 (related)
H00019 Pancreatic cancer P04637 (related)
P04637 (marker)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00022 Bladder cancer P04637 (related)
H00025 Penile cancer P04637 (related)
P04637 (marker)
H00026 Endometrial Cancer P04637 (related)
H00027 Ovarian cancer P04637 (related)
H00028 Choriocarcinoma P04637 (related)
H00029 Vulvar cancer P04637 (related)
H00031 Breast cancer P04637 (related)
H00032 Thyroid cancer P04637 (related)
H00033 Adrenal carcinoma P04637 (related)
H00036 Osteosarcoma P04637 (related)
H00038 Malignant melanoma P04637 (related)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00042 Glioma P04637 (related)
P04637 (marker)
H00044 Cancer of the anal canal P04637 (related)
H00046 Cholangiocarcinoma P04637 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00055 Laryngeal cancer P04637 (related)
P04637 (marker)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00021 Renal cell carcinoma P04637 (marker)
H00213 Hypophosphatasia P05186 (related)
H00023 Testicular cancer P10696 (marker)
H00024 Prostate cancer P11308 (related)
H00035 Ewing's sarcoma P11308 (related)
H00552 Glycerol kinase deficiency (GKD) P51843 (related)
H00607 46,XY disorders of sex development (Disorders of gonadal development) P51843 (related)
H00296 Defects in RecQ helicases Q14191 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)