| Organism name | Hydrangea macrophylla var. thunbergii |
|---|---|
| Genus | Hydrangea |
| Family | Hydrangeaceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Hydrangea |
|---|---|
| Linked NCBI taxonomy ID | 23109 |
| Linked level | genus |
| Family in NCBI taxonomy | Hydrangeaceae |
|---|---|
| ID | 23097 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | asterids |
|---|---|
| ID | 71274 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00015274
|
Thunberginol A
/ 3-(3,4-dihydroxyphenyl)-8-hydroxyisocoumarin |
CHEMBL68810
|
C079055
|
14 / 5 / 4 | No. 54 | No. 17 |
|
|
|
C00050256
|
Thunberginol B
|
CHEMBL70501
|
C079056
|
20 / 16 / 45 | No. 54 | No. 17 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00015274 C00050256 | 0 / 0 |
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00015274 C00050256 | 2 / 1 |
| Q9H0H5 | Rac GTPase-activating protein 1 | Unclassified protein | C00015274 C00050256 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00015274 C00050256 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00015274 C00050256 | 0 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00015274 C00050256 | 0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00015274 C00050256 | 1 / 1 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00015274 C00050256 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00015274 C00050256 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00015274 C00050256 | 0 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00015274 C00050256 | 0 / 0 |
| P11021 | 78 kDa glucose-regulated protein | Unclassified protein | C00050256 | 0 / 0 |
| P51843 | Nuclear receptor subfamily 0 group B member 1 | Nuclear hormone receptor subfamily 0 group B member 1 | C00050256 | 2 / 2 |
| P10696 | Alkaline phosphatase, placental-like | Enzyme | C00050256 | 0 / 1 |
| P11308 | Transcriptional regulator ERG | Unclassified protein | C00050256 | 1 / 2 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00050256 | 0 / 0 |
| P05186 | Alkaline phosphatase, tissue-nonspecific isozyme | Enzyme | C00050256 | 3 / 1 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00015274 | 0 / 0 |
| P09923 | Intestinal-type alkaline phosphatase | Enzyme | C00050256 | 0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00015274 | 0 / 0 |
| P17405 | Sphingomyelin phosphodiesterase | Enzyme | C00015274 | 2 / 2 |
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00050256 | 7 / 37 |
| Q9HCT0 | Fibroblast growth factor 22 | Unclassified protein | C00050256 | 0 / 0 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #300018 | 46,xy sex reversal 2; srxy2 |
P51843
|
| #300200 | Adrenal hypoplasia, congenital; ahc |
P51843
|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #114500 | Colorectal cancer; crc |
Q14191
|
| #133239 | Esophageal cancer |
P04637
|
| #612219 | Ewing sarcoma; es |
P11308
|
| #146300 | Hypophosphatasia, adult |
P05186
|
| #241510 | Hypophosphatasia, childhood |
P05186
|
| #241500 | Hypophosphatasia, infantile |
P05186
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #211980 | Lung cancer |
P04637
|
| #257200 | Niemann-pick disease, type a |
P17405
|
| #607616 | Niemann-pick disease, type b |
P17405
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| #277700 | Werner syndrome; wrn |
Q14191
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
| KEGG | name | UniProt |
|---|---|---|
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00016 | Oral cancer |
P04637
(related)
P04637 (marker) |
| H00017 | Esophageal cancer |
P04637
(related)
P04637 (marker) |
| H00018 | Gastric cancer |
P04637
(related)
|
| H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00022 | Bladder cancer |
P04637
(related)
|
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) |
| H00026 | Endometrial Cancer |
P04637
(related)
|
| H00027 | Ovarian cancer |
P04637
(related)
|
| H00028 | Choriocarcinoma |
P04637
(related)
|
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00031 | Breast cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
|
| H00033 | Adrenal carcinoma |
P04637
(related)
|
| H00036 | Osteosarcoma |
P04637
(related)
|
| H00038 | Malignant melanoma |
P04637
(related)
|
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00042 | Glioma |
P04637
(related)
P04637 (marker) |
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00046 | Cholangiocarcinoma |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00055 | Laryngeal cancer |
P04637
(related)
P04637 (marker) |
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00021 | Renal cell carcinoma |
P04637
(marker)
|
| H00213 | Hypophosphatasia |
P05186
(related)
|
| H00023 | Testicular cancer |
P10696
(marker)
|
| H00024 | Prostate cancer |
P11308
(related)
|
| H00035 | Ewing's sarcoma |
P11308
(related)
|
| H00137 | Niemann-Pick disease (NPD) typeA and B |
P17405
(related)
|
| H00424 | Defects in the degradation of sphingomyelin |
P17405
(related)
|
| H00552 | Glycerol kinase deficiency (GKD) |
P51843
(related)
|
| H00607 | 46,XY disorders of sex development (Disorders of gonadal development) |
P51843
(related)
|
| H00296 | Defects in RecQ helicases |
Q14191
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|