PCIDB

KNApSAcK Metabolite C00000560

Metabolite

KNApSAcK Entry

id C00000560
Name Averufin
CAS RN 14016-29-6
Standard InChI InChI=1S/C20H16O7/c1-20-4-2-3-12(26-20)16-13(27-20)7-10-15(19(16)25)18(24)14-9(17(10)23)5-8(21)6-11(14)22/h5-7,12,21-22,25H,2-4H2,1H3
Standard InChI (Main Layer) InChI=1S/C20H16O7/c1-20-4-2-3-12(26-20)16-13(27-20)7-10-15(19(16)25)18(24)14-9(17(10)23)5-8(21)6-11(14)22/h5-7,12,21-22,25H,2-4H2,1H3

Cluster

Phytochemical cluster No. 62
KCF-S cluster No. 581

Link

ChEMBL

By standard InChI
By standard InChI Main Layer CHEMBL1706207

KEGG

By LinkDB

CTD

By CAS RN C029856

Human Protein / Gene in interaction

15 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q99700 Ataxin-2 Unclassified protein CHEMBL1706207 CHEMBL2114784 (1)
1 / 1
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme CHEMBL1706207 CHEMBL1794585 (1)
0 / 0
P17405 Sphingomyelin phosphodiesterase Enzyme CHEMBL1706207 CHEMBL1794495 (1)
2 / 2
P39748 Flap endonuclease 1 Enzyme CHEMBL1706207 CHEMBL1794486 (1)
0 / 0
O75496 Geminin Unclassified protein CHEMBL1706207 CHEMBL2114843 (1)
0 / 0
Q9Y253 DNA polymerase eta Enzyme CHEMBL1706207 CHEMBL1794569 (1)
1 / 1
P11308 Transcriptional regulator ERG Unclassified protein CHEMBL1706207 CHEMBL2114924 (1)
1 / 2
P83916 Chromobox protein homolog 1 Unclassified protein CHEMBL1706207 CHEMBL1794401 (1)
0 / 0
Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G Enzyme CHEMBL1706207 CHEMBL1963863 (1) CHEMBL2114898 (1)
CHEMBL2114934 (1)
0 / 0
P08253 72 kDa type IV collagenase M10A CHEMBL1706207 CHEMBL1964000 (1)
1 / 3
Q9UNA4 DNA polymerase iota Enzyme CHEMBL1706207 CHEMBL1794483 (1)
0 / 0
O75164 Lysine-specific demethylase 4A Enzyme CHEMBL1706207 CHEMBL1737991 (1)
0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme CHEMBL1706207 CHEMBL1964002 (1)
1 / 0
Q8IUX4 DNA dC->dU-editing enzyme APOBEC-3F Enzyme CHEMBL1706207 CHEMBL1963966 (1) CHEMBL2114859 (1)
CHEMBL2114734 (1)
0 / 0
O00487 26S proteasome non-ATPase regulatory subunit 14 Enzyme CHEMBL1706207 CHEMBL1963965 (1)
0 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (7)

OMIM preferred title UniProt
#612219 Ewing sarcoma; es P11308
#137800 Glioma susceptibility 1; glm1 O75874
#259600 Multicentric osteolysis, nodulosis, and arthropathy; mona P08253
#257200 Niemann-pick disease, type a P17405
#607616 Niemann-pick disease, type b P17405
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (9)

KEGG disease name UniProt
H00025 Penile cancer P08253 (related)
H00028 Choriocarcinoma P08253 (related)
H00472 Torg-Winchester syndrome P08253 (related)
H00024 Prostate cancer P11308 (related)
H00035 Ewing's sarcoma P11308 (related)
H00137 Niemann-Pick disease (NPD) typeA and B P17405 (related)
H00424 Defects in the degradation of sphingomyelin P17405 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)