Species

KNApSAcK Entry

Organism name Aspergillus versicolor
Genus Aspergillus
Family Trichocomaceae
Kingdom Fungi

NCBI taxonomy

Entry

Linked NCBI taxonomy name Aspergillus versicolor
Linked NCBI taxonomy ID 46472
Linked level species

Family

Family in NCBI taxonomy Aspergillaceae
ID 1131492

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Fungi
ID 4751

Plant class

Plant class
ID

Metabolite list (20)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00000560 External link 512 Averufin
CHEMBL1706207
C029856
15 / 7 / 9 No. 581 No. 62
C00000562 External link 512 Versicolorin B
No. 581 No. 62
C00023630 External link 512 Aversin
No. 581 No. 62
C00023627 External link 512 Versicolorin C
C029827
No. 581 No. 62
C00023626 External link 512 Versicolorin A
C029826
No. 581 No. 62
C00047429 External link 512 Cotteslosin B
CHEMBL556170
No. 745
C00047428 External link 512 Cotteslosin A
No. 745
C00047430 External link 512 Cottoquinazoline A
/ (+)-Cottoquinazoline A
No. 964
C00023638 External link 512 Sterigmatin
No. 1133
C00036630 External link 512 6-Methoxysterigmatocystin
No. 1133
C00023637 External link 512 5-Methoxysterigmatocystin
CHEMBL1541017
CHEMBL1973034
7 / 17 / 8 No. 1133
C00023633 External link 512 Dihydrosterigmatocystin
/ 1,2-Dihydro-6-methoxy-7-hydroxyfuroxanthone
No. 1133
C00000563 External link 512 Sterigmatocystin
CHEMBL524291
CHEMBL1532401
D013241
9 / 3 No. 1133
C00044547 External link 512 Aspergione C
/ (+)-Aspergione C
CHEMBL507994
No. 2654
C00044545 External link 512 Aspergione A
/ (+)-Aspergione A
No. 2654
C00044549 External link 512 Aspergione E
/ (+)-Aspergione E
CHEMBL453547
No. 2654
C00044550 External link 512 Aspergione F
/ (-)-Aspergione F
No. 2654
C00044548 External link 512 Aspergione D
/ (+)-Aspergione D
No. 3235 No. 25
C00044544 External link 512 Aspergillitine
CHEMBL453286
No. 3235 No. 25
C00044546 External link 512 Aspergione B
/ (+)-Aspergione B
CHEMBL120182
No. 5294

Human Protein / Gene in interactions

22 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q99700 Ataxin-2 Unclassified protein C00000560 1 / 1
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00000560 0 / 0
P37840 Alpha-synuclein Unclassified protein C00023637 4 / 2
P17405 Sphingomyelin phosphodiesterase Enzyme C00000560 2 / 2
P39748 Flap endonuclease 1 Enzyme C00000560 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00023637 2 / 0
O75496 Geminin Unclassified protein C00000560 0 / 0
P51151 Ras-related protein Rab-9A Unclassified protein C00023637 0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00023637 7 / 3
Q9Y253 DNA polymerase eta Enzyme C00000560 1 / 1
P11308 Transcriptional regulator ERG Unclassified protein C00000560 1 / 2
P83916 Chromobox protein homolog 1 Unclassified protein C00000560 0 / 0
Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G Enzyme C00000560 0 / 0
P08253 72 kDa type IV collagenase M10A C00000560 1 / 3
Q9UNA4 DNA polymerase iota Enzyme C00000560 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00000560 0 / 0
P61088 Ubiquitin-conjugating enzyme E2 N Enzyme C00023637 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00023637 4 / 3
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00023637 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00000560 1 / 0
Q8IUX4 DNA dC->dU-editing enzyme APOBEC-3F Enzyme C00000560 0 / 0
O00487 26S proteasome non-ATPase regulatory subunit 14 Enzyme C00000560 0 / 0

9 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
891 CCNB1, CCNB cyclin B1 C00000563
995 CDC25C, CDC25, PPP1R60 cell division cycle 25C (EC:3.1.3.48) C00000563
983 CDK1, CDC2, CDC28A, P34CDC2 cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) C00000563
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00000563
1544 CYP1A2, CP12, P3-450, P450(PA) cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) C00000563
1576 CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) C00000563
4292 MLH1, COCA2, FCC2, HNPCC, HNPCC2, hMLH1 mutL homolog 1 C00000563
4436 MSH2, COCA1, FCC1, HNPCC, HNPCC1, LCFS2 mutS homolog 2 C00000563
7508 XPC, RAD4, XP3, XPCC xeroderma pigmentosum, complementation group C C00000563

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (24)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#114500 Colorectal cancer; crc P84022
#127750 Dementia, lewy body; dlb P37840
#612219 Ewing sarcoma; es P11308
#600274 Frontotemporal dementia; ftd P10636
#137800 Glioma susceptibility 1; glm1 O75874
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#174800 Mccune-albright syndrome; mas P63092
#259600 Multicentric osteolysis, nodulosis, and arthropathy; mona P08253
#257200 Niemann-pick disease, type a P17405
#607616 Niemann-pick disease, type b P17405
#166350 Osseous heteroplasia, progressive; poh P63092
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P37840
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (17)

KEGG name UniProt
H00025 Penile cancer P08253 (related)
H00028 Choriocarcinoma P08253 (related)
H00472 Torg-Winchester syndrome P08253 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00024 Prostate cancer P11308 (related)
H00035 Ewing's sarcoma P11308 (related)
H00137 Niemann-Pick disease (NPD) typeA and B P17405 (related)
H00424 Defects in the degradation of sphingomyelin P17405 (related)
H00057 Parkinson's disease (PD) P37840 (related)
H00066 Lewy body dementia (LBD) P37840 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

3 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D007249 Inflammation C00000563
D008114 Liver Neoplasms, Experimental C00000563
D011041 Poisoning C00000563