KNApSAcK Metabolite C00000608
Metabolite
KNApSAcK Entry
| id | C00000608 |
|---|---|
| Name | (+)-Arctigenin |
| CAS RN | 84413-77-4 |
| Standard InChI | InChI=1S/C21H24O6/c1-24-18-7-5-13(11-20(18)26-3)8-15-12-27-21(23)16(15)9-14-4-6-17(22)19(10-14)25-2/h4-7,10-11,15-16,22H,8-9,12H2,1-3H3/t15-,16-/m1/s1 |
| Standard InChI (Main Layer) | InChI=1S/C21H24O6/c1-24-18-7-5-13(11-20(18)26-3)8-15-12-27-21(23)16(15)9-14-4-6-17(22)19(10-14)25-2/h4-7,10-11,15-16,22H,8-9,12H2,1-3H3 |
Cluster
| Phytochemical cluster | No. 21 |
|---|---|
| KCF-S cluster | No. 223 |
Link
ChEMBL
| By standard InChI | |
|---|---|
| By standard InChI Main Layer | CHEMBL369142 CHEMBL435734 CHEMBL1966556 |
KEGG
| By LinkDB |
|---|
CTD
| By CAS RN |
|---|
Species
Summary
Plant class
| class name | count |
|---|---|
| rosids | 1 |
Family
| family name | count |
|---|---|
| Thymelaeaceae | 1 |
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Wikstroemia indica | 714517 | Thymelaeaceae | rosids | Viridiplantae |
Human Protein / Gene in interaction
13 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | CHEMBL435734 |
CHEMBL1741321
(1)
|
1 / 0 |
| Q02750 | Dual specificity mitogen-activated protein kinase kinase 1 | Ste7 | CHEMBL435734 |
CHEMBL921092
(1)
|
1 / 1 |
| Q99700 | Ataxin-2 | Unclassified protein | CHEMBL369142 |
CHEMBL2114784
(1)
|
1 / 1 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | CHEMBL435734 |
CHEMBL1614027
(1)
CHEMBL1741325
(1)
|
0 / 1 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | CHEMBL369142 |
CHEMBL1794584
(1)
|
2 / 0 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | CHEMBL369142 |
CHEMBL1613838
(1)
|
0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | CHEMBL369142 |
CHEMBL2114788
(1)
|
0 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | CHEMBL435734 |
CHEMBL1613808
(1)
|
0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | CHEMBL435734 |
CHEMBL1741322
(1)
|
0 / 0 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | CHEMBL369142 |
CHEMBL1614342
(1)
|
1 / 1 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | CHEMBL435734 |
CHEMBL1613777
(1)
CHEMBL1741323
(1)
|
1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | CHEMBL435734 |
CHEMBL1614108
(1)
CHEMBL1613886
(1)
CHEMBL1741324 (1) |
0 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | CHEMBL369142 |
CHEMBL1794483
(1)
|
0 / 0 |
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (7)
| OMIM | preferred title | UniProt |
|---|---|---|
| #615279 | Cardiofaciocutaneous syndrome 3; cfc3 |
Q02750
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
KEGG DISEASE (6)
| KEGG | disease name | UniProt |
|---|---|---|
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00523 | Noonan syndrome and related disorders |
Q02750
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|