PCIDB

KNApSAcK Metabolite C00006097

Metabolite

KNApSAcK Entry

id C00006097
Name 8-C-beta-D-Galactopyranosylapigenin
CAS RN 35013-07-1
Standard InChI InChI=1S/C21H20O10/c22-7-14-17(27)18(28)19(29)21(31-14)16-11(25)5-10(24)15-12(26)6-13(30-20(15)16)8-1-3-9(23)4-2-8/h1-6,14,17-19,21-25,27-29H,7H2/t14?,17-,18-,19?,21-/m0/s1
Standard InChI (Main Layer) InChI=1S/C21H20O10/c22-7-14-17(27)18(28)19(29)21(31-14)16-11(25)5-10(24)15-12(26)6-13(30-20(15)16)8-1-3-9(23)4-2-8/h1-6,14,17-19,21-25,27-29H,7H2

Cluster

Phytochemical cluster No. 15
KCF-S cluster No. 22

Link

ChEMBL

By standard InChI
By standard InChI Main Layer CHEMBL487417 CHEMBL1332209 CHEMBL1357921

KEGG

By LinkDB

CTD

By CAS RN

Human Protein / Gene in interaction

16 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 CHEMBL1357921 CHEMBL1741321 (1)
1 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme CHEMBL1332209 CHEMBL1794585 (1)
0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 CHEMBL1357921 CHEMBL1741325 (1)
0 / 1
O75496 Geminin Unclassified protein CHEMBL1332209 CHEMBL2114843 (1) CHEMBL2114780 (1)
0 / 0
P15121 Aldose reductase Enzyme CHEMBL487417 CHEMBL1942674 (1)
0 / 0
Q9Y253 DNA polymerase eta Enzyme CHEMBL1332209 CHEMBL1794569 (1)
1 / 1
Q9Y468 Lethal(3)malignant brain tumor-like protein 1 Unclassified protein CHEMBL1332209 CHEMBL1614280 (1)
0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 CHEMBL1357921 CHEMBL1741322 (1)
0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 CHEMBL1357921 CHEMBL1741323 (1)
1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL1357921 CHEMBL1741324 (1)
0 / 1
Q9UNA4 DNA polymerase iota Enzyme CHEMBL1332209 CHEMBL1794483 (1)
0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme CHEMBL487417 CHEMBL1357921 CHEMBL1614211 (2)
0 / 0
Q9UBT6 DNA polymerase kappa Enzyme CHEMBL487417 CHEMBL1332209 CHEMBL1794536 (2)
0 / 0
Q13951 Core-binding factor subunit beta Unclassified protein CHEMBL487417 CHEMBL1613933 (1)
0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein CHEMBL487417 CHEMBL1613933 (1)
1 / 6
O94925 Glutaminase kidney isoform, mitochondrial Enzyme CHEMBL1332209 CHEMBL2114738 (1)
0 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (4)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (8)

KEGG disease name UniProt
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)