KNApSAcK Metabolite C00000706
Metabolite
KNApSAcK Entry
| id | C00000706 |
|---|---|
| Name | Phyllanthin |
| CAS RN | 10351-88-9 |
| Standard InChI | InChI=1S/C24H34O6/c1-25-15-19(11-17-7-9-21(27-3)23(13-17)29-5)20(16-26-2)12-18-8-10-22(28-4)24(14-18)30-6/h7-10,13-14,19-20H,11-12,15-16H2,1-6H3/t19-,20-/m0/s1 |
| Standard InChI (Main Layer) | InChI=1S/C24H34O6/c1-25-15-19(11-17-7-9-21(27-3)23(13-17)29-5)20(16-26-2)12-18-8-10-22(28-4)24(14-18)30-6/h7-10,13-14,19-20H,11-12,15-16H2,1-6H3 |
Cluster
| Phytochemical cluster | No. 21 |
|---|---|
| KCF-S cluster | No. 1232 |
Link
ChEMBL
| By standard InChI | CHEMBL453568 |
|---|---|
| By standard InChI Main Layer | CHEMBL453568 CHEMBL1253999 |
KEGG
| By LinkDB | C10746 |
|---|
CTD
| By CAS RN |
|---|
Species
Summary
Plant class
| class name | count |
|---|---|
| rosids | 3 |
Family
| family name | count |
|---|---|
| Phyllanthaceae | 3 |
List (3)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Phyllanthus amarus Schum. & Thonn. | 233880 | Phyllanthaceae | rosids | Viridiplantae |
| Phyllanthus niruri | 296034 | Phyllanthaceae | rosids | Viridiplantae |
| Phyllanthus urinaria L. | 296035 | Phyllanthaceae | rosids | Viridiplantae |
Human Protein / Gene in interaction
3 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| P24530 | Endothelin B receptor | Endothelin receptor | CHEMBL453568 |
CHEMBL937908
(1)
|
4 / 4 |
| P25101 | Endothelin-1 receptor | Endothelin receptor | CHEMBL453568 |
CHEMBL937907
(1)
|
0 / 0 |
| O14746 | Telomerase reverse transcriptase | Enzyme | CHEMBL453568 |
CHEMBL1251398
(1)
|
5 / 5 |
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (9)
| OMIM | preferred title | UniProt |
|---|---|---|
| #600501 | Abcd syndrome; abcds |
P24530
|
| #609135 | Aplastic anemia |
O14746
|
| #613989 | Dyskeratosis congenita, autosomal dominant, 2; dkca2 |
O14746
|
| #142623 | Hirschsprung disease, susceptibility to, 1; hscr1 |
P24530
|
| #600155 | Hirschsprung disease, susceptibility to, 2; hscr2 |
P24530
|
| #615134 | Melanoma, cutaneous malignant, susceptibility to, 9; cmm9 |
O14746
|
| #614742 | Pulmonary fibrosis and/or bone marrow failure, telomere-related, 1; pfbmft1 |
O14746
|
| #178500 | Pulmonary fibrosis, idiopathic; ipf |
O14746
|
| #277580 | Waardenburg syndrome, type 4a; ws4a |
P24530
|
KEGG DISEASE (9)
| KEGG | disease name | UniProt |
|---|---|---|
| H00764 | Cri du chat syndrome |
O14746
(related)
|
| H01132 | Aplastic anemia (AA) |
O14746
(related)
|
| H01299 | Idiopathic pulmonary fibrosis |
O14746
(related)
|
| H00022 | Bladder cancer |
O14746
(marker)
|
| H00024 | Prostate cancer |
O14746
(marker)
|
| H00054 | Nasopharyngeal cancer |
P24530
(related)
|
| H00759 | Waardenburg syndrome (WS) |
P24530
(related)
|
| H00823 | ABCD syndrome |
P24530
(related)
|
| H00910 | Hirschsprung disease (HD) |
P24530
(related)
|