KCF-S cluster No. 1232 (8 metabolites)

Corresponding Phytochemical cluster No. 21

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (8)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
rosids	6
Magnoliophyta	6
asterids	1

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Cumulative family count

class name	count
Phyllanthaceae	5
Piperaceae	4
Hernandiaceae	1
Plantaginaceae	1
Burseraceae	1
Schisandraceae	1

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Lignans	2

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metabolites link (2)

br08003 Category	KEGG ID	KNApSAcK ID
Lignans	C10547	C00000705
Lignans	C10746	C00000706

Metabolite list (8)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00000705	(-)-Burseran	CHEMBL157013
C00000706	Phyllanthin	CHEMBL453568 CHEMBL1253999		3 / 9 / 9
C00030823	Niranthin		C475932
C00041984	Clusin / (-)-Clusin	CHEMBL479701 CHEMBL476708		2 / 1 / 1
C00041985	(-)-Cubebinin	CHEMBL480296		2 / 1 / 1
C00041986	(-)-Dihydroclusin	CHEMBL469916		2 / 1 / 1
C00042499	Ethoxyclusin / (-)-Ethoxyclusin
C00047598	Tiegusanin N	CHEMBL556989

Human Protein / Gene in interactions

5 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00041984 C00041985 C00041986	1 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00041984 C00041985 C00041986	0 / 1
P25101	Endothelin-1 receptor	Endothelin receptor	C00000706	0 / 0
P24530	Endothelin B receptor	Endothelin receptor	C00000706	4 / 4
O14746	Telomerase reverse transcriptase	Enzyme	C00000706	5 / 5

Related Diseases

Diseases related to proteins in ChEMBL interactions