KNApSAcK Metabolite C00000757
Metabolite
KNApSAcK Entry
| id | C00000757 |
|---|---|
| Name | Dethiobiotin |
| CAS RN | 533-48-2 |
| Standard InChI | InChI=1S/C10H18N2O3/c1-7-8(12-10(15)11-7)5-3-2-4-6-9(13)14/h7-8H,2-6H2,1H3,(H,13,14)(H2,11,12,15)/t7-,8+/m0/s1 |
| Standard InChI (Main Layer) | InChI=1S/C10H18N2O3/c1-7-8(12-10(15)11-7)5-3-2-4-6-9(13)14/h7-8H,2-6H2,1H3,(H,13,14)(H2,11,12,15) |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 3747 |
Link
ChEMBL
| By standard InChI | CHEMBL1232381 |
|---|---|
| By standard InChI Main Layer | CHEMBL1232381 |
KEGG
| By LinkDB | C01909 |
|---|
CTD
| By CAS RN |
|---|
Species
Summary
Plant class
| class name | count |
|---|
Family
| family name | count |
|---|---|
| Bacillaceae | 1 |
| Enterobacteriaceae | 1 |
List (2)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Bacillus subtilis | 1423 | Bacillaceae | Bacteria | |
| Escherichia coli | 562 | Enterobacteriaceae | Bacteria |
Human Protein / Gene in interaction
11 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| Q9Y5X4 | Photoreceptor-specific nuclear receptor | NR2E3 | CHEMBL1232381 |
CHEMBL1613893
(1)
|
2 / 2 |
| P14735 | Insulin-degrading enzyme | Enzyme | CHEMBL1232381 |
CHEMBL1794358
(1)
CHEMBL1794445
(1)
|
0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | CHEMBL1232381 |
CHEMBL1794584
(1)
|
2 / 0 |
| O75496 | Geminin | Unclassified protein | CHEMBL1232381 |
CHEMBL2114843
(1)
|
0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | CHEMBL1232381 |
CHEMBL1794569
(1)
|
1 / 1 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | CHEMBL1232381 |
CHEMBL1794401
(1)
|
0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | CHEMBL1232381 |
CHEMBL1737991
(1)
|
0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | CHEMBL1232381 |
CHEMBL2354311
(1)
|
1 / 0 |
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | CHEMBL1232381 |
CHEMBL1614465
(1)
|
5 / 3 |
| Q9Y618 | Nuclear receptor corepressor 2 | Unclassified protein | CHEMBL1232381 |
CHEMBL1614465
(1)
|
0 / 0 |
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | CHEMBL1232381 |
CHEMBL2114796
(1)
|
2 / 1 |
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (11)
| OMIM | preferred title | UniProt |
|---|---|---|
| %606641 | Body mass index; bmi |
P37231
|
| #609338 | Carotid intimal medial thickness 1 |
P37231
|
| #114500 | Colorectal cancer; crc |
P84022
Q14191 |
| #268100 | Enhanced s-cone syndrome; escs |
Q9Y5X4
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
P37231 |
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #601665 | Obesity |
P37231
|
| #611131 | Retinitis pigmentosa 37; rp37 |
Q9Y5X4
|
| #277700 | Werner syndrome; wrn |
Q14191
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG DISEASE (7)
| KEGG | disease name | UniProt |
|---|---|---|
| H00032 | Thyroid cancer |
P37231
(related)
|
| H00409 | Type II diabetes mellitus |
P37231
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P37231
(related)
|
| H00296 | Defects in RecQ helicases |
Q14191
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|
| H00527 | Retinitis pigmentosa (RP) |
Q9Y5X4
(related)
|
| H00805 | Vitreoretinal degeneration |
Q9Y5X4
(related)
|