Bacillus subtilis

• Index
• Plant Species
• Metabolite list (12)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Bacillus subtilis
Genus	Bacillus
Family	Bacillaceae
Kingdom	Bacteria

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Bacillus subtilis
Linked NCBI taxonomy ID	1423
Linked level	species

Family

Family in NCBI taxonomy	Bacillaceae
ID	186817

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Bacteria
ID	2

Plant class

Plant class
ID

Metabolite list (12)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00019756	Daidzein 7-O-(6''-succinylglucoside) / 7,4'-Dihydroxyisoflavone 7-O-(6''-succinylglucoside)					No. 2	No. 15
C00019757	Genistein 7-O-(6''-succinylglucoside) / 5,7,4'-Trihydroxyisoflavone 7-O-(6''-succinylglucoside)					No. 2	No. 15
C00019758	Glycitein 7-O-(6''-succinylglucoside) / 7,4'-Dihydroxy-6-methoxyisoflavone 7-O-(6''-succinylglucoside)					No. 2	No. 15
C00029420	1-Deoxynojirimycin / (+)-1-Deoxynojirimycin	CHEMBL11510 CHEMBL65131 CHEMBL307429 CHEMBL84844 CHEMBL110458 CHEMBL369297 CHEMBL179085 CHEMBL176206 CHEMBL179130 CHEMBL179347 CHEMBL179409 CHEMBL176021 CHEMBL369046 CHEMBL176209 CHEMBL368121 CHEMBL175901 CHEMBL1337303	D017485	33 / 27 / 27		No. 786	No. 1
C00002669	Pyrocatechuic acid / o-Pyrocatechuic acid / 2,3-Dihydroxybenzoic acid	CHEMBL1432	C009135	12 / 6 / 5	1 / 4	No. 817	No. 81
C00000757	Dethiobiotin	CHEMBL1232381		11 / 11 / 7		No. 3747
C00000734	Isochorismic acid		C052985			No. 3811
C00000733	Chorismic acid	CHEMBL1160745	D002827			No. 3811
C00007494	4-Amino-5-hydroxymethyl-2-methylpyrimidine		C012068			No. 5580
C00000759	7,8-Diaminopelargonic acid					No. 5903
C00016740	Bacitracin F		C037039			No. 6080
C00000758	8-Amino-7-oxopelargonic acid					No. 8032

Human Protein / Gene in interactions

55 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
O75164	Lysine-specific demethylase 4A	Enzyme	C00000757 C00002669	0 / 0
P06280	Alpha-galactosidase A	Enzyme	C00029420	1 / 1
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00002669	0 / 0
P21728	D(1A) dopamine receptor	Dopamine receptor	C00029420	0 / 0
P04062	Glucosylceramidase	Enzyme	C00029420	6 / 4
Q14697	Neutral alpha-glucosidase AB	Enzyme	C00029420	0 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00029420	1 / 1
P22894	Neutrophil collagenase	M10A	C00002669	0 / 0
Q9H227	Cytosolic beta-glucosidase	Enzyme	C00029420	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00002669	2 / 2
Q9Y5X4	Photoreceptor-specific nuclear receptor	NR2E3	C00000757	2 / 2
P35573	Glycogen debranching enzyme	Enzyme	C00029420	1 / 1
P14735	Insulin-degrading enzyme	Enzyme	C00000757	0 / 0
P10828	Thyroid hormone receptor beta	NR1A2	C00029420	3 / 1
P16278	Beta-galactosidase	Enzyme	C00029420	4 / 6
P02768	Serum albumin	Secreted protein	C00002669	0 / 0
P04066	Tissue alpha-L-fucosidase	Enzyme	C00029420	1 / 2
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00029420	0 / 1
P23458	Tyrosine-protein kinase JAK1	Jakb	C00029420	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00029420	0 / 0
P16581	E-selectin	Adhesion	C00002669	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00000757	2 / 0
O75496	Geminin	Unclassified protein	C00000757	0 / 0
P14410	Sucrase-isomaltase, intestinal	Enzyme	C00029420	1 / 1
P03956	Interstitial collagenase	M10A	C00002669	0 / 1
Q9Y253	DNA polymerase eta	Enzyme	C00000757	1 / 1
P83916	Chromobox protein homolog 1	Unclassified protein	C00000757	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00002669	1 / 1
Q13133	Oxysterols receptor LXR-alpha	NR1H3	C00029420	0 / 0
O00462	Beta-mannosidase	Enzyme	C00029420	1 / 2
Q9HCG7	Non-lysosomal glucosylceramidase	Enzyme	C00029420	1 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00029420	0 / 0
P08253	72 kDa type IV collagenase	M10A	C00002669	1 / 3
P55055	Oxysterols receptor LXR-beta	NR1H3	C00029420	0 / 0
P09848	Lactase-phlorizin hydrolase	Enzyme	C00029420	1 / 1
Q16739	Ceramide glucosyltransferase	Transferase	C00029420	0 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00029420	0 / 0
P14151	L-selectin	Adhesion	C00002669	0 / 0
P16109	P-selectin	Adhesion	C00002669	1 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00029420	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00029420	0 / 1
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00029420	1 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00029420	0 / 0
O43451	Maltase-glucoamylase, intestinal	Hydrolase	C00029420	0 / 0
O43280	Trehalase	Enzyme	C00029420	0 / 0
P08254	Stromelysin-1	M10A	C00002669	1 / 0
O00754	Lysosomal alpha-mannosidase	Enzyme	C00029420	1 / 2
Q6P4F1	Alpha-(1,3)-fucosyltransferase 10	Enzyme	C00029420	0 / 0
Q9Y2E5	Epididymis-specific alpha-mannosidase	Enzyme	C00029420	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00000757	1 / 0
O00255	Menin	Unclassified protein	C00029420	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00029420	1 / 2
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00000757	5 / 3
Q9Y618	Nuclear receptor corepressor 2	Unclassified protein	C00000757	0 / 0
Q14191	Werner syndrome ATP-dependent helicase	Enzyme	C00000757	2 / 1

1 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
4313	MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24)	C00002669

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions