KNApSAcK Metabolite C00008155
Metabolite
KNApSAcK Entry
| id | C00008155 |
|---|---|
| Name | 8-Hydroxy-5,7-dimethoxyflavanone |
| CAS RN | 75041-38-2 |
| Standard InChI | InChI=1S/C17H16O5/c1-20-13-9-14(21-2)16(19)17-15(13)11(18)8-12(22-17)10-6-4-3-5-7-10/h3-7,9,12,19H,8H2,1-2H3 |
| Standard InChI (Main Layer) | InChI=1S/C17H16O5/c1-20-13-9-14(21-2)16(19)17-15(13)11(18)8-12(22-17)10-6-4-3-5-7-10/h3-7,9,12,19H,8H2,1-2H3 |
Cluster
| Phytochemical cluster | No. 14 |
|---|---|
| KCF-S cluster | No. 25 |
Link
ChEMBL
| By standard InChI | CHEMBL1350188 |
|---|---|
| By standard InChI Main Layer | CHEMBL1350188 |
KEGG
| By LinkDB |
|---|
CTD
| By CAS RN |
|---|
Species
Summary
Plant class
| class name | count |
|---|---|
| Magnoliophyta | 1 |
Family
| family name | count |
|---|---|
| Piperaceae | 1 |
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Piper hispidum | 130401 | Piperaceae | Magnoliophyta | Viridiplantae |
Human Protein / Gene in interaction
21 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| P06746 | DNA polymerase beta | Enzyme | CHEMBL1350188 |
CHEMBL1614079
(1)
CHEMBL1794299
(1)
|
0 / 0 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | CHEMBL1350188 |
CHEMBL1614076
(1)
|
1 / 1 |
| Q15056 | Eukaryotic translation initiation factor 4H | Unclassified protein | CHEMBL1350188 |
CHEMBL1613814
(1)
|
0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | CHEMBL1350188 |
CHEMBL1794311
(1)
|
2 / 3 |
| P39748 | Flap endonuclease 1 | Enzyme | CHEMBL1350188 |
CHEMBL1794486
(1)
|
0 / 0 |
| O75496 | Geminin | Unclassified protein | CHEMBL1350188 |
CHEMBL2114780
(1)
|
0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | CHEMBL1350188 |
CHEMBL1794569
(1)
|
1 / 1 |
| P09923 | Intestinal-type alkaline phosphatase | Enzyme | CHEMBL1350188 |
CHEMBL1738679
(1)
|
0 / 0 |
| P05186 | Alkaline phosphatase, tissue-nonspecific isozyme | Enzyme | CHEMBL1350188 |
CHEMBL1738602
(1)
|
3 / 1 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | CHEMBL1350188 |
CHEMBL1614280
(1)
|
0 / 0 |
| P10696 | Alkaline phosphatase, placental-like | Enzyme | CHEMBL1350188 |
CHEMBL1738040
(1)
|
0 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | CHEMBL1350188 |
CHEMBL1794483
(1)
|
0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | CHEMBL1350188 |
CHEMBL1737991
(1)
|
0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | CHEMBL1350188 |
CHEMBL1614466
(1)
CHEMBL1614211
(1)
|
0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | CHEMBL1350188 |
CHEMBL1614421
(1)
|
4 / 3 |
| P11940 | Polyadenylate-binding protein 1 | Unclassified protein | CHEMBL1350188 |
CHEMBL1614548
(1)
|
0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | CHEMBL1350188 |
CHEMBL1794536
(1)
|
0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | CHEMBL1350188 |
CHEMBL1613829
(1)
|
0 / 0 |
| O00255 | Menin | Unclassified protein | CHEMBL1350188 |
CHEMBL1614257
(1)
|
2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | CHEMBL1350188 |
CHEMBL1614257
(1)
|
1 / 3 |
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | CHEMBL1350188 |
CHEMBL2114796
(1)
|
2 / 1 |
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (16)
| OMIM | preferred title | UniProt |
|---|---|---|
| #114500 | Colorectal cancer; crc |
Q14191
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #232300 | Glycogen storage disease ii |
P10253
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #146300 | Hypophosphatasia, adult |
P05186
|
| #241510 | Hypophosphatasia, childhood |
P05186
|
| #241500 | Hypophosphatasia, infantile |
P05186
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #277700 | Werner syndrome; wrn |
Q14191
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG DISEASE (18)
| KEGG | disease name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00213 | Hypophosphatasia |
P05186
(related)
|
| H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00023 | Testicular cancer |
P10696
(marker)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00296 | Defects in RecQ helicases |
Q14191
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|