PCIDB

KNApSAcK Metabolite C00009765

Metabolite

KNApSAcK Entry

id C00009765
Name Norwedelolactone / Demethylwedelolactone / Desmethylwedelolactone
CAS RN 6468-55-9
Standard InChI InChI=1S/C15H8O7/c16-5-1-9(19)13-11(2-5)22-15(20)12-6-3-7(17)8(18)4-10(6)21-14(12)13/h1-4,16-19H
Standard InChI (Main Layer) InChI=1S/C15H8O7/c16-5-1-9(19)13-11(2-5)22-15(20)12-6-3-7(17)8(18)4-10(6)21-14(12)13/h1-4,16-19H

Cluster

Phytochemical cluster No. 17
KCF-S cluster No. 54

Link

ChEMBL

By standard InChI CHEMBL2089002
By standard InChI Main Layer CHEMBL2089002

KEGG

By LinkDB

CTD

By CAS RN C051123

Human Protein / Gene in interaction

6 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P25963 NF-kappa-B inhibitor alpha Other cytosolic protein CHEMBL2089002 CHEMBL2091591 (1) CHEMBL2091593 (1)
1 / 2
P14780 Matrix metalloproteinase-9 M10A CHEMBL2089002 CHEMBL2089632 (1)
2 / 2
P28482 Mitogen-activated protein kinase 1 Erk CHEMBL2089002 CHEMBL2091594 (1)
0 / 0
P27361 Mitogen-activated protein kinase 3 Erk CHEMBL2089002 CHEMBL2091594 (1)
0 / 0
Q05397 Focal adhesion kinase 1 Fak CHEMBL2089002 CHEMBL2089629 (1)
0 / 0
P08253 72 kDa type IV collagenase M10A CHEMBL2089002 CHEMBL2089631 (1)
1 / 3

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (4)

OMIM preferred title UniProt
#612132 Ectodermal dysplasia, anhidrotic, with t-cell immunodeficiency, autosomal dominant P25963
#603932 Intervertebral disc disease; idd P14780
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#259600 Multicentric osteolysis, nodulosis, and arthropathy; mona P08253

KEGG DISEASE (6)

KEGG disease name UniProt
H00025 Penile cancer P08253 (related)
P14780 (related)
H00028 Choriocarcinoma P08253 (related)
H00472 Torg-Winchester syndrome P08253 (related)
H00479 Metaphyseal dysplasias P14780 (related)
H00007 Hodgkin lymphoma P25963 (related)
H00095 Ectodermal dysplasia associated immunodeficiency (EDA-ID) P25963 (related)