KCF-S cluster No. 1013 (9 metabolites)

Corresponding Phytochemical cluster No. 15


KEGG BRITE br08003 External link 512


Categories (1)

br08003 Category # of metabolite
Chromones 2

metabolites link (2)

br08003 Category KEGG ID KNApSAcK ID
Chromones C08994 C00002415
Chromones C08996 C00002417

Metabolite list (9)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00002415 External link 512 Aloesin
/ Aloe resin B
CHEMBL1343351
C069868
4 / 7 / 3
C00002417 External link 512 Biflorin
CHEMBL463312
C00029994 External link 512 Cnidimoside A
CHEMBL1329158
CHEMBL2087917
1 / 1 / 1
C00030518 External link 512 Isobiflorin
C00032440 External link 512 Uncinoside A
CHEMBL2164950
C00032441 External link 512 Uncinoside B
C00036661 External link 512 7-O-Methylaloesin
/ (-)-7-O-Methylaloesin
C00042148 External link 512 5,7-Dihydroxy-2-isopropylchromone-8-beta-D-glucoside
/ (+)-5,7-Dihydroxy-2-isopropylchromone-8-beta-D-glucoside
CHEMBL463692
C00042182 External link 512 8-C-Glucosyl-7-O-methylaloediol

Human Protein / Gene in interactions

5 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00002415 7 / 3
Q9Y253 DNA polymerase eta Enzyme C00029994 1 / 1
P83916 Chromobox protein homolog 1 Unclassified protein C00002415 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00002415 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00002415 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (8)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#174800 Mccune-albright syndrome; mas P63092
#166350 Osseous heteroplasia, progressive; poh P63092
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (4)

KEGG name UniProt
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)