| class name | count |
|---|---|
| rosids | 22 |
| eudicotyledons | 1 |
| asterids | 1 |
| class name | count |
|---|---|
| Fabaceae | 22 |
| Daphniphyllaceae | 1 |
| Styracaceae | 1 |
| br08003 Category | # of metabolite |
|---|---|
| Quinolizidine alkaloids | 1 |
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|---|---|
| Quinolizidine alkaloids | C10749 | C00007758 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00007695
|
Lupanine N-oxide
|
|
||||
|
C00007751
|
Multiflorine N-oxide
|
|
||||
|
C00007758
|
Oxymatrine
/ Ammothamnine / Matrine N-oxide / (+)-Matrine N-oxide / Matrine 1beta-oxide |
CHEMBL458337
CHEMBL1358502 |
C037573
|
3 / 11 / 6 | 0 / 4 |
|
|
C00007760
|
Sophocarpine N-oxide
/ (+)-Sophocarpine N-oxide |
CHEMBL380410
|
C046246
|
|
||
|
C00007782
|
Camoensidine N-oxide
|
|
||||
|
C00023307
|
(+)-Sophoranol N-oxide
|
|
||||
|
C00026281
|
(-)-Sophoridine N-oxide
|
CHEMBL458337
CHEMBL1358502 |
3 / 11 / 6 |
|
||
|
C00026318
|
5,6-Dehydroisolupanine
|
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00007758 C00026281 | 7 / 3 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00007758 C00026281 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00007758 C00026281 | 4 / 3 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| KEGG | name | UniProt |
|---|---|---|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|