KCF-S cluster No. 1355 (7 metabolites)

Corresponding Phytochemical cluster No. 1

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (7)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
asterids	13
rosids	4

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Cumulative family count

class name	count
Convolvulaceae	10
Solanaceae	3
Erythroxylaceae	2
Phyllanthaceae	1
Rhizophoraceae	1

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Tropane alkaloids	3

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metabolites link (3)

br08003 Category	KEGG ID	KNApSAcK ID
Tropane alkaloids	C10854	C00002287
Tropane alkaloids	C10856	C00002289
Tropane alkaloids	C10863	C00002298

Metabolite list (7)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00002287	Convolamine	CHEMBL1514821 CHEMBL1907009		5 / 2 / 3
C00002288	Convoline	CHEMBL1890337		1 / 0 / 0
C00002289	Convolvine
C00002298	Phyllalbine	CHEMBL1375175 CHEMBL1555308 CHEMBL2165592		9 / 10 / 8
C00036530	3alpha-(3,4,5-Trimethoxybenzoyloxy)nortropan-6beta-ol
C00036531	3alpha-(3,4,5-Trimethoxybenzoyloxy)nortropane
C00036930	Convolidine	CHEMBL1384086		5 / 3 / 7

Human Protein / Gene in interactions

13 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00002287 C00002298	1 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00002287 C00002298	0 / 1
O75496	Geminin	Unclassified protein	C00002288 C00002298	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00002287 C00002298	0 / 1
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00002287 C00002298	1 / 1
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00002298 C00036930	1 / 2
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00002287 C00002298	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00002298	7 / 3
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00002298	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00036930	0 / 0
O00167	Eyes absent homolog 2	Enzyme	C00036930	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00036930	0 / 0
O00255	Menin	Unclassified protein	C00036930	2 / 5

Related Diseases

Diseases related to proteins in ChEMBL interactions