KCF-S cluster No. 1538 (6 metabolites)
Plant Species
Cumulative plant class count
| class name | count |
|---|---|
| rosids | 5 |
| Spermatophyta | 2 |
| Liliopsida | 1 |
| asterids | 1 |
Cumulative family count
| class name | count |
|---|---|
| Fabaceae | 3 |
| Brassicaceae | 2 |
| Cycadaceae | 2 |
| Asparagaceae | 1 |
| Enterobacteriaceae | 1 |
| Solanaceae | 1 |
| Streptomycetaceae | 1 |
KEGG BRITE br08003
Categories (0)
| br08003 Category | # of metabolite |
|---|
metabolites link (0)
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
Metabolite list (6)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00001353
|
L-alpha,gamma-Diaminobutyric acid
|
CHEMBL307931
CHEMBL102493 CHEMBL321357 |
5 / 2 / 3 |
|
||
|
C00001378
|
L-Lysine
|
CHEMBL8085
CHEMBL28328 CHEMBL319497 |
5 / 12 / 11 |
|
||
|
C00001380
|
3-Methylamino-L-alanine
|
CHEMBL11488
CHEMBL1486321 |
1 / 1 / 1 |
|
||
|
C00001384
|
L-Ornithine
|
CHEMBL446143
CHEMBL103686 CHEMBL2009502 |
6 / 5 / 6 |
|
||
|
C00018075
|
L-2-Amino-4-(2-aminoethoxy)butanoic acid
|
|
||||
|
C00045681
|
beta-Methylaminoalanine
|
CHEMBL11488
CHEMBL1486321 |
1 / 1 / 1 |
|
Human Protein / Gene in interactions
12 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001353 C00001384 | 1 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00001380 C00045681 | 1 / 1 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001353 C00001384 | 0 / 1 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001353 C00001384 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001353 C00001384 | 0 / 1 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001353 C00001384 | 1 / 1 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00001384 | 3 / 3 |
| P00390 | Glutathione reductase, mitochondrial | Oxidoreductase | C00001378 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00001378 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00001378 | 11 / 10 |
| Q9H015 | Solute carrier family 22 member 4 | Unclassified protein | C00001378 | 1 / 1 |
| Q05BR4 | SLC16A10 protein | Unclassified protein | C00001378 | 0 / 0 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (18)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #180300 | Rheumatoid arthritis; ra |
Q9H015
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
KEGG DISEASE (18)
| KEGG | name | UniProt |
|---|---|---|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00286 | Crohn's disease |
Q9H015
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|