KCF-S cluster No. 2351 (4 metabolites)

Corresponding Phytochemical cluster No. 4

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (4)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
rosids	7
eudicotyledons	1
asterids	1

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Cumulative family count

class name	count
Malpighiaceae	4
Thorectidae	2
Polygonaceae	1
Fabaceae	1
Rubiaceae	1
Nitrariaceae	1
Elaeagnaceae	1

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Indole alkaloids	1

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metabolites link (1)

br08003 Category	KEGG ID	KNApSAcK ID
Indole alkaloids	C09243	C00001774

Metabolite list (4)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00001699	Calligonine	CHEMBL440524		1 / 0 / 0
C00001774	Tetrahydroharmine	CHEMBL129208	C035525	17 / 10 / 14
C00026847	1,6-Dihydroxy-1,2,3,4-tetrahydro-beta-carboline
C00045191	6-Hydroxy-3,4-dihydro-1-oxo-beta-carboline	CHEMBL397215

Human Protein / Gene in interactions

17 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P47898	5-hydroxytryptamine receptor 5A	Serotonin receptor	C00001699 C00001774	0 / 0
P08253	72 kDa type IV collagenase	M10A	C00001774	1 / 3
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00001774	1 / 1
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00001774	0 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00001774	0 / 0
P17405	Sphingomyelin phosphodiesterase	Enzyme	C00001774	2 / 2
P39748	Flap endonuclease 1	Enzyme	C00001774	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00001774	1 / 1
P06746	DNA polymerase beta	Enzyme	C00001774	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00001774	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00001774	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00001774	4 / 3
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00001774	0 / 0
O00487	26S proteasome non-ATPase regulatory subunit 14	Enzyme	C00001774	0 / 0
Q13951	Core-binding factor subunit beta	Unclassified protein	C00001774	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00001774	1 / 4
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00001774	0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions