| class name | count | 
|---|
| class name | count | 
|---|
 
                  
                | br08003 Category | # of metabolite | 
|---|
| br08003 Category | KEGG ID | KNApSAcK ID | 
|---|
| KNApSAcK ID | name | ChEMBL link | CTD link | # of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE | # of genes in CTD interaction / related diseases | figure | 
|---|---|---|---|---|---|---|
| C00046781   | Isomalyngamide A / (-)-Isomalyngamide A | CHEMBL1357867 CHEMBL2147270 | 15 / 15 / 48 |   | ||
| C00046782   | Isomalyngamide B / (+)-Isomalyngamide B | CHEMBL1702391 | 12 / 16 / 7 |   | ||
| C00046816   | Malyngamide Q / (+)-Malyngamide Q |   | ||||
| C00046817   | Malyngamide R / (+)-Malyngamide R |   | 
| accession | description | class description | KNApSAcK metabolite in interactions | # of diseases (OMIM / KEGG) | 
|---|---|---|---|---|
| Q99700 | Ataxin-2 | Unclassified protein | C00046781 C00046782 | 1 / 1 | 
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00046781 C00046782 | 1 / 0 | 
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00046781 C00046782 | 0 / 0 | 
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00046781 C00046782 | 0 / 0 | 
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00046781 C00046782 | 0 / 0 | 
| O75496 | Geminin | Unclassified protein | C00046781 C00046782 | 0 / 0 | 
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00046781 C00046782 | 2 / 0 | 
| Q9Y253 | DNA polymerase eta | Enzyme | C00046781 | 1 / 1 | 
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00046782 | 0 / 0 | 
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00046782 | 7 / 3 | 
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | C00046781 | 0 / 1 | 
| P37840 | Alpha-synuclein | Unclassified protein | C00046782 | 4 / 2 | 
| P51843 | Nuclear receptor subfamily 0 group B member 1 | Nuclear hormone receptor subfamily 0 group B member 1 | C00046781 | 2 / 2 | 
| Q13315 | Serine-protein kinase ATM | Atypical serine/threonine protein kinase PIKK subfamily | C00046781 | 1 / 4 | 
| Q9UNA4 | DNA polymerase iota | Enzyme | C00046781 | 0 / 0 | 
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00046782 | 0 / 0 | 
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00046781 | 7 / 37 | 
| Q8IUX4 | DNA dC->dU-editing enzyme APOBEC-3F | Enzyme | C00046781 | 0 / 0 | 
| P01215 | Glycoprotein hormones alpha chain | Unclassified protein | C00046781 | 0 / 3 | 
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00046782 | 1 / 1 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| #300018 | 46,xy sex reversal 2; srxy2 | P51843 | 
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah | P63092 | 
| #300200 | Adrenal hypoplasia, congenital; ahc | P51843 | 
| #202300 | Adrenocortical carcinoma, hereditary; adcc | P04637 | 
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 | Q13148 | 
| #208900 | Ataxia-telangiectasia; at | Q13315 | 
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 | P04637 | 
| #114500 | Colorectal cancer; crc | P84022 | 
| #127750 | Dementia, lewy body; dlb | P37840 | 
| #133239 | Esophageal cancer | P04637 | 
| #137800 | Glioma susceptibility 1; glm1 | O75874 | 
| #151623 | Li-fraumeni syndrome 1; lfs1 | P04637 | 
| #613795 | Loeys-dietz syndrome, type 3; lds3 | P84022 | 
| #211980 | Lung cancer | P04637 | 
| #174800 | Mccune-albright syndrome; mas | P63092 | 
| #166350 | Osseous heteroplasia, progressive; poh | P63092 | 
| #260500 | Papilloma of choroid plexus; cpp | P04637 | 
| #168601 | Parkinson disease 1, autosomal dominant; park1 | P37840 | 
| #605543 | Parkinson disease 4, autosomal dominant; park4 | P37840 | 
| #168600 | Parkinson disease, late-onset; pd | P37840 | 
| #102200 | Pituitary adenoma, growth hormone-secreting | P63092 | 
| #103580 | Pseudohypoparathyroidism, type ia; php1a | P63092 | 
| #603233 | Pseudohypoparathyroidism, type ib; php1b | P63092 | 
| #612462 | Pseudohypoparathyroidism, type ic; php1c | P63092 | 
| #183090 | Spinocerebellar ataxia 2; sca2 | Q99700 | 
| #275355 | Squamous cell carcinoma, head and neck; hnscc | P04637 | 
| #278750 | Xeroderma pigmentosum, variant type; xpv | Q9Y253 | 
| KEGG | name | UniProt | 
|---|---|---|
| H00081 | Hashimoto's thyroiditis | P01215
                            (marker) | 
| H00082 | Graves' disease | P01215
                            (marker) | 
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) | P01215
                            (marker) | 
| H00004 | Chronic myeloid leukemia (CML) | P04637
                            (related) | 
| H00005 | Chronic lymphocytic leukemia (CLL) | P04637
                            (related) Q13315 (related) | 
| H00006 | Hairy-cell leukemia | P04637
                            (related) | 
| H00008 | Burkitt lymphoma | P04637
                            (related) | 
| H00009 | Adult T-cell leukemia | P04637
                            (related) | 
| H00010 | Multiple myeloma | P04637
                            (related) | 
| H00013 | Small cell lung cancer | P04637
                            (related) | 
| H00014 | Non-small cell lung cancer | P04637
                            (related) | 
| H00015 | Malignant pleural mesothelioma | P04637
                            (related) | 
| H00016 | Oral cancer | P04637
                            (related) P04637 (marker) | 
| H00017 | Esophageal cancer | P04637
                            (related) P04637 (marker) | 
| H00018 | Gastric cancer | P04637
                            (related) | 
| H00019 | Pancreatic cancer | P04637
                            (related) P04637 (marker) | 
| H00020 | Colorectal cancer | P04637
                            (related) P04637 (marker) | 
| H00022 | Bladder cancer | P04637
                            (related) | 
| H00025 | Penile cancer | P04637
                            (related) P04637 (marker) | 
| H00026 | Endometrial Cancer | P04637
                            (related) | 
| H00027 | Ovarian cancer | P04637
                            (related) | 
| H00028 | Choriocarcinoma | P04637
                            (related) | 
| H00029 | Vulvar cancer | P04637
                            (related) | 
| H00031 | Breast cancer | P04637
                            (related) | 
| H00032 | Thyroid cancer | P04637
                            (related) | 
| H00033 | Adrenal carcinoma | P04637
                            (related) | 
| H00036 | Osteosarcoma | P04637
                            (related) | 
| H00038 | Malignant melanoma | P04637
                            (related) | 
| H00039 | Basal cell carcinoma | P04637
                            (related) | 
| H00040 | Squamous cell carcinoma | P04637
                            (related) | 
| H00041 | Kaposi's sarcoma | P04637
                            (related) | 
| H00042 | Glioma | P04637
                            (related) P04637 (marker) | 
| H00044 | Cancer of the anal canal | P04637
                            (related) | 
| H00046 | Cholangiocarcinoma | P04637
                            (related) | 
| H00047 | Gallbladder cancer | P04637
                            (related) | 
| H00048 | Hepatocellular carcinoma | P04637
                            (related) | 
| H00055 | Laryngeal cancer | P04637
                            (related) P04637 (marker) | 
| H00881 | Li-Fraumeni syndrome | P04637
                            (related) | 
| H01007 | Choroid plexus papilloma | P04637
                            (related) | 
| H00021 | Renal cell carcinoma | P04637
                            (marker) | 
| H00079 | Asthma | P07550
                            (related) | 
| H00057 | Parkinson's disease (PD) | P37840
                            (related) | 
| H00066 | Lewy body dementia (LBD) | P37840
                            (related) | 
| H00552 | Glycerol kinase deficiency (GKD) | P51843
                            (related) | 
| H00607 | 46,XY disorders of sex development (Disorders of gonadal development) | P51843
                            (related) | 
| H00244 | Pseudohypoparathyroidism | P63092
                            (related) | 
| H00441 | Progressive osseous heteroplasia (POH) | P63092
                            (related) | 
| H00501 | Fibrous dysplasia, polyostotic | P63092
                            (related) | 
| H00058 | Amyotrophic lateral sclerosis (ALS) | Q13148
                            (related) | 
| H00064 | Ataxia telangiectasia (AT) | Q13315
                            (related) | 
| H00094 | DNA repair defects | Q13315
                            (related) | 
| H00848 | Ataxia with ocular apraxia (AOA) | Q13315
                            (related) | 
| H00063 | Spinocerebellar ataxia (SCA) | Q99700
                            (related) | 
| H00403 | Disorders of nucleotide excision repair | Q9Y253
                            (related) |