KCF-S cluster No. 364 (20 metabolites)

Corresponding Phytochemical cluster No. 25

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (20)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
asterids	19
rosids	17
eudicotyledons	2

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Cumulative family count

class name	count
Rutaceae	6
Asteraceae	6
Apiaceae	4
Geraniaceae	3
Lamiaceae	3
Polemoniaceae	3
Meliaceae	3
Amaranthaceae	2
Malvaceae	2
Oleaceae	1
Convolvulaceae	1
Fabaceae	1
Euphorbiaceae	1
Davidiellaceae	1
Ebenaceae	1
Sapindaceae	1

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Coumarins	2

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metabolites link (2)

br08003 Category	KEGG ID	KNApSAcK ID
Coumarins	C09271	C00002479
Coumarins	C09313	C00002501

Metabolite list (20)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00002479	Leptodactylone	CHEMBL595334
C00002501	5,6,7-Trimethoxycoumarin	CHEMBL607537
C00019318	Fraxinol / 5,7-Dimethoxy-6-hydroxycoumarin	CHEMBL611349
C00019766	7-Acetoxy-5,6-dimethoxycoumarin
C00019839	6,8-Dihydroxy-5,7-dimethoxycoumarin
C00019875	Fraxidin	CHEMBL2334351		6 / 2 / 4
C00019970	Murrayacarpin B
C00020020	Schinicoumarin
C00030527	Isofraxidin	CHEMBL451518	C008182
C00031438	Yunngnin A
C00032667	6,7,8-Trimethoxy-2H-1-benzopyran-2-one	CHEMBL253551		10 / 7 / 9
C00038274	4,6-Dimethoxy-5-methylcoumarin
C00038858	Coumarsabin
C00039097	Ekersenin / Pereflorin
C00040304	Siderin
C00042174	7-Hydroxy-4-methoxy-5-methylcoumarin / 7-hydroxy-4-methoxy-5-methyl-2H-1-Benzopyran-2-one
C00044065	5,7,8-Trimethoxycoumarin	CHEMBL596221		6 / 2 / 4
C00044478	7,8-Dimethoxy-6-hydroxycoumarin	CHEMBL469432
C00048300	7-Hydroxy-3-methoxypereflorin
C00050406	Umckalin

Human Protein / Gene in interactions

10 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P43166	Carbonic anhydrase 7	Lyase	C00019875 C00032667 C00044065	0 / 0
Q8N1Q1	Carbonic anhydrase 13	Lyase	C00019875 C00032667 C00044065	0 / 0
P00918	Carbonic anhydrase 2	Lyase	C00019875 C00032667 C00044065	1 / 2
Q16790	Carbonic anhydrase 9	Lyase	C00019875 C00032667 C00044065	0 / 1
O43570	Carbonic anhydrase 12	Lyase	C00019875 C00032667 C00044065	1 / 2
P00915	Carbonic anhydrase 1	Lyase	C00019875 C00032667 C00044065	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00032667	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00032667	3 / 3
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00032667	2 / 2
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00032667	0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions