KCF-S cluster No. 384 (19 metabolites)

Corresponding Phytochemical cluster No. 3

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (19)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
rosids	196
eudicotyledons	9

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Cumulative family count

class name	count
Fabaceae	196
Berberidaceae	6
Daphniphyllaceae	2
Viscaceae	1

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Quinolizidine alkaloids	6

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metabolites link (7)

br08003 Category	KEGG ID	KNApSAcK ID
Quinolizidine alkaloids	C10750	C00002207
Quinolizidine alkaloids	C10755	C00002212
Quinolizidine alkaloids	C10758	C00002215
Quinolizidine alkaloids	C10782	C00002235
Quinolizidine alkaloids	C10789	C00002238
Quinolizidine alkaloids	C10790	C00002239
Quinolizidine alkaloids	C10755	C00007722

Metabolite list (19)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00002207	Anagyrine / (-)-Anagyrine	CHEMBL203399 CHEMBL509692 CHEMBL1324708 CHEMBL1454284	C012736	7 / 8 / 11
C00002212	Baptifoline / (-)-Baptifoline		C106940
C00002215	Camoensine
C00002235	Sophoramine		C055681
C00002238	Thermopsine / (-)-Thermopsine	CHEMBL203399 CHEMBL509692 CHEMBL1324708 CHEMBL1454284	C059560	7 / 8 / 11
C00002239	Tinctorine / (-)-Tinctorine
C00007722	Epibaptifoline / (-)-Epibaptifoline
C00007723	13beta-Hydroxythermopsine
C00007724	O-Acetylbaptifolin
C00007729	11alpha-Allylcytisine
C00007750	5,6-Dehydromultiflorine
C00023310	(-)-9alpha-Hydroxysophoramine
C00025370	Leontidine
C00026270	(-)-Argentamine / (-)-13-Hydroxythermopsine
C00026271	(-)-Clathrotropine
C00026319	7alpha-Hydroxysophoramine
C00026320	Acetylepibaptifoline / O-Acetylepibaptifoline
C00026324	Dehydrobaptifoline
C00026337	Isotinctorine

Human Protein / Gene in interactions

7 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00002207 C00002238	1 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00002207 C00002238	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00002207 C00002238	3 / 3
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00002207 C00002238	1 / 1
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00002207 C00002238	0 / 0
O00255	Menin	Unclassified protein	C00002207 C00002238	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00002207 C00002238	1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions