KNApSAcK Metabolite C00002207
Metabolite
KNApSAcK Entry
| id | C00002207 |
|---|---|
| Name | Anagyrine / (-)-Anagyrine |
| CAS RN | 486-89-5 |
| Standard InChI | InChI=1S/C15H20N2O/c18-15-6-3-5-14-11-8-12(10-17(14)15)13-4-1-2-7-16(13)9-11/h3,5-6,11-13H,1-2,4,7-10H2/t11?,12?,13-/m1/s1 |
| Standard InChI (Main Layer) | InChI=1S/C15H20N2O/c18-15-6-3-5-14-11-8-12(10-17(14)15)13-4-1-2-7-16(13)9-11/h3,5-6,11-13H,1-2,4,7-10H2 |
Cluster
| Phytochemical cluster | No. 3 |
|---|---|
| KCF-S cluster | No. 384 |
Link
ChEMBL
| By standard InChI | CHEMBL203399 |
|---|---|
| By standard InChI Main Layer | CHEMBL203399 CHEMBL509692 CHEMBL1324708 CHEMBL1454284 |
KEGG
| By LinkDB | C10750 |
|---|
CTD
| By CAS RN | C012736 |
|---|
Species
Summary
Plant class
| class name | count |
|---|---|
| rosids | 111 |
| eudicotyledons | 3 |
Family
| family name | count |
|---|---|
| Fabaceae | 111 |
| Berberidaceae | 1 |
| Daphniphyllaceae | 1 |
| Viscaceae | 1 |
List (115)
* NCBI
Human Protein / Gene in interaction
7 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | CHEMBL1454284 |
CHEMBL1614110
(1)
|
1 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | CHEMBL203399 |
CHEMBL1614458
(1)
|
0 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | CHEMBL1454284 |
CHEMBL1614227
(1)
|
3 / 3 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | CHEMBL1454284 |
CHEMBL1613777
(1)
|
1 / 1 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | CHEMBL203399 CHEMBL1324708 |
CHEMBL1613914
(2)
|
0 / 0 |
| O00255 | Menin | Unclassified protein | CHEMBL203399 |
CHEMBL1614531
(1)
|
2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | CHEMBL203399 |
CHEMBL1614531
(1)
|
1 / 3 |
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (8)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
KEGG DISEASE (11)
| KEGG | disease name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|