Genista aetnensis
Species
KNApSAcK Entry
| Organism name | Genista aetnensis |
|---|---|
| Genus | Genista |
| Family | Fabaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Genista aetnensis |
|---|---|
| Linked NCBI taxonomy ID | 49819 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Fabaceae |
|---|---|
| ID | 3803 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Metabolite list (8)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00002528
|
Genistin
/ Genistoside / Genistein 7-O-glucoside / Genistein 7-O-beta-glucopyranoside |
CHEMBL486625
CHEMBL1364260 |
C040641
|
15 / 32 / 53 | 6 / 2 | No. 2 | No. 15 |
|
|
C00004635
|
Isorhamnetin
/ 3'-O-Methylquercetin / 3,4',5,7-Tetrahydroxy-3'-methoxyflavone / 3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one |
CHEMBL379064
|
C047368
|
12 / 10 / 13 | 10 / 0 | No. 3 | No. 15 |
|
|
C00009452
|
Isoprunetin
/ 5-O-Methylgenistein |
CHEMBL1479463
|
6 / 0 / 0 | No. 3 | No. 15 |
|
||
|
C00001060
|
Kaempferide
|
CHEMBL40919
|
6 / 7 / 4 | No. 3 | No. 15 |
|
||
|
C00002525
|
Formononetin
/ 7-Hydroxy-4'-methoxyisoflavone |
CHEMBL242341
|
C007768
|
24 / 36 / 58 | 13 / 0 | No. 3 | No. 15 |
|
|
C00002216
|
Caulophylline
/ N-Methylcytisine / (-)-N-Methylcytisine |
CHEMBL66191
CHEMBL1085045 |
C034245
|
No. 376 | No. 3 |
|
||
|
C00002207
|
Anagyrine
/ (-)-Anagyrine |
CHEMBL203399
CHEMBL509692 CHEMBL1324708 CHEMBL1454284 |
C012736
|
7 / 8 / 11 | No. 384 | No. 3 |
|
|
|
C00002236
|
Spartein
/ (-)-Spartein |
CHEMBL412873
CHEMBL44625 CHEMBL172633 CHEMBL1328708 CHEMBL1492771 CHEMBL1740920 CHEMBL1908847 CHEMBL2010478 |
D013034
|
93 / 50 / 48 | 1 / 2 | No. 424 | No. 3 |
|
Human Protein / Gene in interactions
133 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00002207 C00002236 C00002525 C00004635 | 1 / 2 |
| O00255 | Menin | Unclassified protein | C00002207 C00002236 C00002525 C00004635 | 2 / 5 |
| P04798 | Cytochrome P450 1A1 | Cytochrome P450 1A1 | C00001060 C00002525 C00004635 | 0 / 0 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00002207 C00002236 C00002525 | 1 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00002207 C00002525 C00009452 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001060 C00002236 C00004635 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00002207 C00002236 C00002525 | 1 / 1 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00002525 C00002528 | 2 / 2 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00002525 C00002528 | 0 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00002528 C00009452 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00002236 C00002525 | 0 / 1 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00002207 C00002525 | 3 / 3 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00002525 C00002528 | 4 / 1 |
| Q16678 | Cytochrome P450 1B1 | Cytochrome P450 1B1 | C00001060 C00004635 | 4 / 4 |
| P38398 | Breast cancer type 1 susceptibility protein | Enzyme | C00002525 C00002528 | 4 / 2 |
| O75496 | Geminin | Unclassified protein | C00002528 C00009452 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00002207 C00002525 | 0 / 0 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00002236 C00002528 | 1 / 8 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00002236 C00002525 | 0 / 1 |
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00002525 C00002528 | 7 / 37 |
| P02545 | Prelamin-A/C | Unclassified protein | C00002236 C00002528 | 11 / 10 |
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00002236 | 0 / 0 |
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00004635 | 1 / 1 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00002236 | 1 / 2 |
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | C00002236 | 0 / 1 |
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00002236 | 1 / 1 |
| P25021 | Histamine H2 receptor | Histamine receptor | C00002236 | 0 / 0 |
| P35367 | Histamine H1 receptor | Histamine receptor | C00002236 | 0 / 0 |
| Q01959 | Sodium-dependent dopamine transporter | Dopamine | C00002236 | 1 / 0 |
| P08912 | Muscarinic acetylcholine receptor M5 | Acetylcholine receptor | C00002236 | 0 / 0 |
| P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | C00002236 | 0 / 0 |
| P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | C00002236 | 0 / 0 |
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00002525 | 0 / 0 |
| P08183 | Multidrug resistance protein 1 | drug | C00001060 | 1 / 0 |
| P25024 | C-X-C chemokine receptor type 1 | CXC chemokine receptor | C00002236 | 0 / 0 |
| P06241 | Tyrosine-protein kinase Fyn | Src | C00002236 | 0 / 0 |
| Q08209 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Ser_Thr | C00002236 | 0 / 0 |
| P27361 | Mitogen-activated protein kinase 3 | Erk | C00002236 | 0 / 0 |
| P04792 | Heat shock protein beta-1 | Unclassified protein | C00004635 | 2 / 1 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00002528 | 1 / 0 |
| P17252 | Protein kinase C alpha type | Alpha | C00002236 | 0 / 0 |
| P14416 | D(2) dopamine receptor | Dopamine receptor | C00002236 | 2 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00002236 | 0 / 0 |
| P37288 | Vasopressin V1a receptor | Vasopressin and oxytocin receptor | C00002236 | 0 / 0 |
| P41145 | Kappa-type opioid receptor | Opioid receptor | C00002236 | 0 / 0 |
| Q9Y271 | Cysteinyl leukotriene receptor 1 | Leukotriene receptor | C00002236 | 0 / 0 |
| P29274 | Adenosine receptor A2a | Adenosine receptor | C00002236 | 0 / 0 |
| P25929 | Neuropeptide Y receptor type 1 | Neuropeptide Y receptor | C00002236 | 0 / 0 |
| P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | C00002236 | 1 / 1 |
| P17948 | Vascular endothelial growth factor receptor 1 | Vegfr | C00002236 | 0 / 0 |
| P41968 | Melanocortin receptor 3 | Melanocortin receptor | C00002236 | 1 / 0 |
| P29466 | Caspase-1 | C14 | C00002236 | 0 / 0 |
| P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | C00002236 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00004635 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00002236 | 0 / 0 |
| P49146 | Neuropeptide Y receptor type 2 | Neuropeptide Y receptor | C00002236 | 0 / 0 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00002528 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00009452 | 0 / 0 |
| P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | C00002236 | 0 / 0 |
| P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | C00002236 | 0 / 0 |
| P21917 | D(4) dopamine receptor | Dopamine receptor | C00002236 | 0 / 0 |
| P30988 | Calcitonin receptor | Calcitonin receptor | C00002236 | 0 / 0 |
| P35462 | D(3) dopamine receptor | Dopamine receptor | C00002236 | 1 / 0 |
| P41143 | Delta-type opioid receptor | Opioid receptor | C00002236 | 0 / 0 |
| Q92731 | Estrogen receptor beta | NR3A2 | C00002236 | 0 / 1 |
| P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | C00002236 | 0 / 0 |
| P25101 | Endothelin-1 receptor | Endothelin receptor | C00002236 | 0 / 0 |
| P30411 | B2 bradykinin receptor | Bradykinin receptor | C00002236 | 0 / 0 |
| P32245 | Melanocortin receptor 4 | Melanocortin receptor | C00002236 | 1 / 0 |
| P32238 | Cholecystokinin receptor type A | Cholecystokinin receptor | C00002236 | 0 / 0 |
| P08311 | Cathepsin G | S1A | C00002236 | 0 / 0 |
| Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | C00002236 | 1 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00009452 | 0 / 0 |
| P03956 | Interstitial collagenase | M10A | C00002236 | 0 / 1 |
| P32241 | Vasoactive intestinal polypeptide receptor 1 | Vasoactive intestinal peptide receptor | C00002236 | 0 / 0 |
| P11021 | 78 kDa glucose-regulated protein | Unclassified protein | C00002525 | 0 / 0 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00002236 | 0 / 1 |
| P08172 | Muscarinic acetylcholine receptor M2 | Acetylcholine receptor | C00002236 | 2 / 0 |
| P11229 | Muscarinic acetylcholine receptor M1 | Acetylcholine receptor | C00002236 | 0 / 0 |
| P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | C00002236 | 0 / 0 |
| P31645 | Sodium-dependent serotonin transporter | Serotonin | C00002236 | 2 / 0 |
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00002525 | 5 / 3 |
| P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | C00002236 | 5 / 9 |
| P20309 | Muscarinic acetylcholine receptor M3 | Acetylcholine receptor | C00002236 | 1 / 0 |
| Q16539 | Mitogen-activated protein kinase 14 | p38 | C00002236 | 0 / 0 |
| P21452 | Substance-K receptor | Neurokinin receptor | C00002236 | 0 / 0 |
| P51679 | C-C chemokine receptor type 4 | CC chemokine receptor | C00002236 | 0 / 0 |
| P51681 | C-C chemokine receptor type 5 | CC chemokine receptor | C00002236 | 3 / 0 |
| P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | C00002236 | 0 / 0 |
| P04745 | Alpha-amylase 1 | Enzyme | C00004635 | 0 / 0 |
| P41597 | C-C chemokine receptor type 2 | CC chemokine receptor | C00002236 | 1 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00002236 | 0 / 0 |
| P08575 | Receptor-type tyrosine-protein phosphatase C | Enzyme | C00002236 | 2 / 1 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00002236 | 0 / 0 |
| P08246 | Neutrophil elastase | S1A | C00002236 | 2 / 1 |
| Q9UNQ0 | ATP-binding cassette sub-family G member 2 | ATP binding cassette | C00001060 | 2 / 0 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00002236 | 2 / 2 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00002528 | 1 / 1 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00002236 | 0 / 3 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00002236 | 2 / 2 |
| P03372 | Estrogen receptor | NR3A1 | C00002236 | 1 / 1 |
| P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | C00002236 | 1 / 0 |
| P22303 | Acetylcholinesterase | Hydrolase | C00002236 | 1 / 0 |
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00002236 | 0 / 0 |
| P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | C00002236 | 0 / 0 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00002236 | 0 / 0 |
| P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | C00002236 | 0 / 0 |
| P25103 | Substance-P receptor | Neurokinin receptor | C00002236 | 0 / 0 |
| P25105 | Platelet-activating factor receptor | PAF receptor | C00002236 | 0 / 0 |
| P33032 | Melanocortin receptor 5 | Melanocortin receptor | C00002236 | 0 / 0 |
| Q02880 | DNA topoisomerase 2-beta | Isomerase | C00001060 | 0 / 0 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00002236 | 0 / 0 |
| P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00004635 | 0 / 0 |
| P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | C00002236 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00009452 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00004635 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00002525 | 4 / 3 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00002528 | 0 / 0 |
| P23975 | Sodium-dependent noradrenaline transporter | Norepinephrine | C00002236 | 1 / 1 |
| P25100 | Alpha-1D adrenergic receptor | Adrenergic receptor | C00002236 | 0 / 0 |
| P30542 | Adenosine receptor A1 | Adenosine receptor | C00002236 | 0 / 0 |
| Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00002525 | 0 / 0 |
| P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | C00002236 | 0 / 0 |
| P24557 | Thromboxane-A synthase | Cytochrome P450 5A1 | C00002236 | 1 / 1 |
| P06239 | Tyrosine-protein kinase Lck | Src | C00002236 | 0 / 1 |
| P25025 | C-X-C chemokine receptor type 2 | CXC chemokine receptor | C00002236 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00004635 | 0 / 0 |
| P31639 | Sodium/glucose cotransporter 2 | Glucose | C00002525 | 1 / 1 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00002528 | 1 / 0 |
| P13866 | Sodium/glucose cotransporter 1 | Glucose | C00002525 | 1 / 1 |
| P33527 | Multidrug resistance-associated protein 1 | drugs | C00002525 | 0 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00002525 | 0 / 0 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00002528 | 1 / 1 |
24 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 5243 | ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) |
C00002525
C00004635
|
| 4363 | ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
C00002525
C00004635
|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00002525
C00004635
|
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00002525
C00004635
|
| 2100 | ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2 | estrogen receptor 2 (ER beta) |
C00002525
C00004635
|
| 2099 | ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 | estrogen receptor 1 |
C00002525
C00004635
|
| 54600 | UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I | UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) |
C00002525
|
| 3091 | HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
C00002525
|
| 54658 | UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A | UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) |
C00002525
|
| 54575 | UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J | UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) |
C00002525
|
| 54577 | UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G | UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) |
C00002525
|
| 54576 | UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H | UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) |
C00002525
|
| 2056 | EPO, EP, MVCD2 | erythropoietin |
C00002525
|
| 2539 | G6PD, G6PD1 | glucose-6-phosphate dehydrogenase (EC:1.1.1.49) |
C00002528
|
| 4489 | MT1A, MT1, MT1S, MTC | metallothionein 1A |
C00002528
|
| 4493 | MT1E, MT1, MTD | metallothionein 1E |
C00002528
|
| 4501 | MT1X, MT-1l, MT1 | metallothionein 1X |
C00002528
|
| 4502 | MT2A, MT2 | metallothionein 2A |
C00002528
|
| 7779 | SLC30A1, ZNT1, ZRC1 | solute carrier family 30 (zinc transporter), member 1 |
C00002528
|
| 196 | AHR, bHLHe76 | aryl hydrocarbon receptor |
C00004635
|
| 4846 | NOS3, ECNOS, eNOS | nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) |
C00004635
|
| 4973 | OLR1, CLEC8A, LOX1, LOXIN, SCARE1, SLOX1 | oxidized low density lipoprotein (lectin-like) receptor 1 |
C00004635
|
| 7031 | TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2 | trefoil factor 1 |
C00004635
|
| 1565 | CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1 | cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1) |
C00002236
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (90)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #100100 | Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism |
P20309
|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #103780 | Alcohol dependence |
P08172
P14416 P31645 |
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #614490 | Blood group, junior system; jr |
Q9UNQ0
|
| #602025 | Body mass index quantitative trait locus 9; bmiq9 |
P41968
|
| %606641 | Body mass index; bmi |
P37231
|
| #114480 | Breast cancer |
P38398
|
| #604370 | Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 |
P38398
|
| #300615 | Brunner syndrome |
P21397
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #609338 | Carotid intimal medial thickness 1 |
P37231
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #606595 | Charcot-marie-tooth disease, axonal, type 2f; cmt2f |
P04792
|
| #162800 | Cyclic neutropenia |
P08246
|
| #612522 | Diabetes mellitus, insulin-dependent, 22; iddm22 |
P51681
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #133239 | Esophageal cancer |
P04637
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #613659 | Gastric cancer |
P04626
|
| #137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
| #231095 | Ghosal hematodiaphyseal dysplasia; ghdd |
P24557
|
| #137750 | Glaucoma 1, open angle, a; glc1a |
Q16678
|
| #231300 | Glaucoma 3, primary congenital, a; glc3a |
Q16678
|
| #137760 | Glaucoma, primary open angle; poag |
Q16678
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
P04626 P37231 |
| #606824 | Glucose/galactose malabsorption; ggm |
P13866
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #609423 | Human immunodeficiency virus type 1, susceptibility to |
P41597
P51681 |
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P00533
P04626 P04637 |
| #608516 | Major depressive disorder; mdd |
P08172
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| %300852 | Mental retardation, x-linked 88; mrx88 |
P50052
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #126200 | Multiple sclerosis, susceptibility to; ms |
P08575
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #159900 | Myoclonic dystonia |
P14416
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #608634 | Neuronopathy, distal hereditary motor, type iib; hmn2b |
P04792
|
| #202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #601665 | Obesity |
P32245
P37231 |
| #164230 | Obsessive-compulsive disorder; ocd |
P31645
|
| #604715 | Orthostatic intolerance |
P23975
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #167000 | Ovarian cancer |
P04626
P38398 |
| #614320 | Pancreatic cancer, susceptibility to, 4; pnca4 |
P38398
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #613135 | Parkinsonism-dystonia, infantile; pkdys |
Q01959
|
| #604229 | Peters anomaly |
Q16678
|
| #172700 | Pick disease of brain |
P10636
|
| #233100 | Renal glucosuria; glys1 |
P31639
|
| #607276 | Resting heart rate, variation in |
P08588
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #608971 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive |
P08575
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #190300 | Tremor, hereditary essential, 1; etm1 |
P35462
|
| #138900 | Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 |
Q9UNQ0
|
| #610379 | West nile virus, susceptibility to |
P51681
|
| #278300 | Xanthinuria, type i |
P47989
|
| #112100 | Yt blood group antigen |
P22303
|
KEGG DISEASE (88)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P04637 (related) P04637 (marker) P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
P04626 (related) P04637 (related) |
| H00022 | Bladder cancer |
P00533
(related)
P04626 (related) P04637 (related) |
| H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P04626 (related) P04637 (related) |
| H00030 | Cervical cancer |
P00533
(related)
P04626 (related) |
| H00042 | Glioma |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
P37231 (related) |
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04626 (related) P04637 (related) Q92731 (marker) |
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
| H00019 | Pancreatic cancer |
P04626
(related)
P04637 (related) P04637 (marker) |
| H00027 | Ovarian cancer |
P04626
(related)
P04637 (related) P38398 (related) |
| H00031 | Breast cancer |
P04626
(related)
P04626 (marker) P04637 (related) P38398 (related) |
| H00046 | Cholangiocarcinoma |
P04626
(related)
P04637 (related) P35354 (related) |
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) P14780 (related) P35354 (related) |
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
P37231 (related) |
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
|
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00021 | Renal cell carcinoma |
P04637
(marker)
|
| H00856 | Distal hereditary motor neuropathies (dHMN) |
P04792
(related)
|
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00079 | Asthma |
P07550
(related)
|
| H00100 | Neutropenic disorders |
P08246
(related)
|
| H00091 | T-B+Severe combined immunodeficiencies (SCIDs) |
P08575
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H01261 | Congenital glucose-galactose malabsorption (GGM) |
P13866
(related)
|
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00548 | Brunner syndrome |
P21397
(related)
|
| H01031 | Orthostatic intolerance (OI) |
P23975
(related)
|
| H00490 | Diaphyseal dysplasia with anemia (Ghosal) |
P24557
(related)
|
| H01126 | Familial renal glucosuria (FRG) |
P31639
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00409 | Type II diabetes mellitus |
P37231
(related)
|
| H00192 | Xanthinuria |
P47989
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
P50052
(related)
Q99714 (related) |
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00612 | Primary open angle glaucoma |
Q16678
(related)
|
| H01075 | Peters anomaly |
Q16678
(related)
|
| H01159 | Anterior segment dysgenesis (ASD) |
Q16678
(related)
|
| H01203 | Primary congenital glaucoma (PCG) |
Q16678
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|