Lygos raetam
Metabolite list (5)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00008041
|
Hispidol 6-glucoside
|
No. 36 | No. 13 |
|
||||
|
C00007703
|
12alpha-Hydroxylupanine
|
No. 85 | No. 3 |
|
||||
|
C00002207
|
Anagyrine
/ (-)-Anagyrine |
CHEMBL203399
CHEMBL509692 CHEMBL1324708 CHEMBL1454284 |
C012736
|
7 / 8 / 11 | No. 384 | No. 3 |
|
|
|
C00002233
|
Retamine
|
No. 424 | No. 3 |
|
||||
|
C00008024
|
Hispidol
|
CHEMBL426110
CHEMBL502446 |
2 / 4 / 2 | No. 450 | No. 13 |
|
Human Protein / Gene in interactions
9 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00002207 | 1 / 0 |
| P15559 | NAD(P)H dehydrogenase [quinone] 1 | Enzyme | C00008024 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00002207 | 0 / 0 |
| P14679 | Tyrosinase | Oxidoreductase | C00008024 | 4 / 2 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00002207 | 3 / 3 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00002207 | 1 / 1 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00002207 | 0 / 0 |
| O00255 | Menin | Unclassified protein | C00002207 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00002207 | 1 / 2 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (12)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
| #203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
| #606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
KEGG DISEASE (13)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
| H00038 | Malignant melanoma |
P14679
(marker)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|