KCF-S cluster No. 5509 (2 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (2)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
rosids	2

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Cumulative family count

class name	count
Brassicaceae	2
Enterobacteriaceae	2

KEGG BRITE br08003

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Categories (0)

br08003 Category	# of metabolite

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metabolites link (0)

br08003 Category	KEGG ID	KNApSAcK ID

Metabolite list (2)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00007230	S-Adenosyl-L-homocysteine	CHEMBL418052 CHEMBL45041 CHEMBL142828 CHEMBL597532 CHEMBL2092997	D012435	10 / 7 / 4	4 / 2
C00007347	S-Adenosyl-L-methionine	CHEMBL224120 CHEMBL1088977 CHEMBL2220241	D012436	4 / 0 / 0	19 / 32

Human Protein / Gene in interactions

13 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q99873	Protein arginine N-methyltransferase 1	Enzyme	C00007230 C00007347	0 / 0
P50135	Histamine N-methyltransferase	Enzyme	C00007230	0 / 0
P49327	Fatty acid synthase	Transferase	C00007230	0 / 0
O43463	Histone-lysine N-methyltransferase SUV39H1	Enzyme	C00007230	0 / 0
Q9UBC3	DNA (cytosine-5)-methyltransferase 3B	Enzyme	C00007230	1 / 1
P22061	Protein-L-isoaspartate(D-aspartate) O-methyltransferase	Enzyme	C00007347	0 / 0
Q8TEK3	Histone-lysine N-methyltransferase, H3 lysine-79 specific	Enzyme	C00007230	0 / 0
Q86X55	Histone-arginine methyltransferase CARM1	Enzyme	C00007230	0 / 0
P26358	DNA (cytosine-5)-methyltransferase 1	Transferase	C00007230	2 / 0
O95050	Indolethylamine N-methyltransferase	Enzyme	C00007230	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00007230	4 / 3
P11086	Phenylethanolamine N-methyltransferase	Enzyme	C00007347	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00007347	0 / 0

20 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
1277	COL1A1, OI4	collagen, type I, alpha 1	C00007230 C00007347
1278	COL1A2, OI4	collagen, type I, alpha 2	C00007230 C00007347
1786	DNMT1, ADCADN, AIM, CXXC9, DNMT, HSN1E, MCMT	DNA (cytosine-5-)-methyltransferase 1 (EC:2.1.1.37)	C00007230 C00007347
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00007347
23743	BHMT2	betaine--homocysteine S-methyltransferase 2 (EC:2.1.1.10)	C00007347
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00007347
1312	COMT	catechol-O-methyltransferase (EC:2.1.1.6)	C00007347
1571	CYP2E1, CPE1, CYP2E, P450-J, P450C2E	cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7)	C00007347
1644	DDC, AADC	dopa decarboxylase (aromatic L-amino acid decarboxylase) (EC:4.1.1.28)	C00007347
1788	DNMT3A, DNMT3A2, M.HsaIIIA	DNA (cytosine-5-)-methyltransferase 3 alpha (EC:2.1.1.37)	C00007347
10891	PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	C00007230
9687	GREB1	growth regulation by estrogen in breast cancer 1	C00007347
3952	LEP, LEPD, OB, OBS	leptin	C00007347
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00007347
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00007347
8932	MBD2, DMTase, NY-CO-41	methyl-CpG binding domain protein 2	C00007347
4548	MTR, HMAG, MS, cblG	5-methyltetrahydrofolate-homocysteine methyltransferase (EC:2.1.1.13)	C00007347
6667	SP1	Sp1 transcription factor	C00007347
7031	TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2	trefoil factor 1	C00007347
7040	TGFB1, CED, DPD1, LAP, TGFB, TGFbeta	transforming growth factor, beta 1	C00007347

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions