KCF-S cluster No. 7714 (1 metabolites)

Corresponding Phytochemical cluster No. 61

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (1)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

---

Cumulative plant class count

class name	count
rosids	2
eudicotyledons	1

---

Cumulative family count

class name	count
Fabaceae	2
Polygonaceae	1

KEGG BRITE br08003

---

Categories (1)

br08003 Category	# of metabolite
Anthrone type	1

---

metabolites link (1)

br08003 Category	KEGG ID	KNApSAcK ID
Anthrone type	C10404	C00002863

Metabolite list (1)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00002863	Sennoside A	CHEMBL54481 CHEMBL448894 CHEMBL445268 CHEMBL1314924 CHEMBL1356785 CHEMBL1362935 CHEMBL1644069		58 / 59 / 53

Human Protein / Gene in interactions

58 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00002863	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00002863	1 / 1
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00002863	2 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00002863	0 / 3
P29466	Caspase-1	C14	C00002863	0 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00002863	0 / 0
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00002863	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00002863	11 / 10
P10828	Thyroid hormone receptor beta	NR1A2	C00002863	3 / 1
P54132	Bloom syndrome protein	Enzyme	C00002863	1 / 2
P11473	Vitamin D3 receptor	NR1I1	C00002863	2 / 3
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00002863	0 / 0
P17405	Sphingomyelin phosphodiesterase	Enzyme	C00002863	2 / 2
P39748	Flap endonuclease 1	Enzyme	C00002863	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00002863	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00002863	2 / 0
O75496	Geminin	Unclassified protein	C00002863	0 / 0
P51151	Ras-related protein Rab-9A	Unclassified protein	C00002863	0 / 0
P38398	Breast cancer type 1 susceptibility protein	Enzyme	C00002863	4 / 2
Q9Y253	DNA polymerase eta	Enzyme	C00002863	1 / 1
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00002863	0 / 0
P11308	Transcriptional regulator ERG	Unclassified protein	C00002863	1 / 2
P83916	Chromobox protein homolog 1	Unclassified protein	C00002863	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00002863	0 / 0
P06280	Alpha-galactosidase A	Enzyme	C00002863	1 / 1
P28482	Mitogen-activated protein kinase 1	Erk	C00002863	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00002863	3 / 3
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00002863	2 / 2
O15118	Niemann-Pick C1 protein	Unclassified protein	C00002863	1 / 1
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00002863	0 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00002863	0 / 0
P55210	Caspase-7	C14	C00002863	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00002863	0 / 1
O75164	Lysine-specific demethylase 4A	Enzyme	C00002863	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00002863	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00002863	4 / 3
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00002863	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00002863	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00002863	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00002863	0 / 0
O00167	Eyes absent homolog 2	Enzyme	C00002863	0 / 0
Q2TB90	Putative hexokinase HKDC1	Enzyme	C00002863	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00002863	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00002863	1 / 1
O00255	Menin	Unclassified protein	C00002863	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00002863	1 / 2
Q13951	Core-binding factor subunit beta	Unclassified protein	C00002863	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00002863	1 / 4
Q92731	Estrogen receptor beta	NR3A2	C00002863	0 / 1
P03372	Estrogen receptor	NR3A1	C00002863	1 / 1
P19429	Troponin I, cardiac muscle	Unclassified protein	C00002863	4 / 4
P45379	Troponin T, cardiac muscle	Unclassified protein	C00002863	3 / 5
P63316	Troponin C, slow skeletal and cardiac muscles	Other cytosolic protein	C00002863	2 / 2
P63165	Small ubiquitin-related modifier 1	Unclassified protein	C00002863	1 / 1
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00002863	0 / 0
Q9H0H5	Rac GTPase-activating protein 1	Unclassified protein	C00002863	0 / 0
Q14191	Werner syndrome ATP-dependent helicase	Enzyme	C00002863	2 / 1
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00002863	1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions