KCF-S cluster No. 822 (11 metabolites)

Corresponding Phytochemical cluster No. 56

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (11)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
asterids	9
eudicotyledons	4
rosids	3
Liliopsida	2

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Cumulative family count

class name	count
Apocynaceae	9
Ranunculaceae	4
Moraceae	2
Asparagaceae	2
Brassicaceae	1

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Cardanolide	1

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metabolites link (1)

br08003 Category	KEGG ID	KNApSAcK ID
Cardanolide	C19988	C00032213

Metabolite list (11)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00030013	Coroglaucigenin	CHEMBL495179
C00032213	Strophanthidin / Strophanthidine / Strophanthidin K	CHEMBL111743 CHEMBL368773 CHEMBL1437139 CHEMBL1516802	D013327	28 / 48 / 65	0 / 1
C00032214	Strophanthidol	CHEMBL1628279
C00032469	Uzarigenin	CHEMBL21214 CHEMBL1453 CHEMBL1591205		33 / 41 / 58
C00032536	Xysmalogenin / 5,6-Dehydrouzarigenin
C00034103	Periforgenin A
C00038847	Coroglaucigenin 3-O-sulfate / (+)-Coroglaucigenin 3-O-sulfate
C00038848	Corotoxigenin 3-O-sulfate / (+)-Corotoxigenin 3-O-sulfate
C00040609	Uzarigenin 3-O-sulfate / (+)-Uzarigenin 3-O-sulfate
C00042202	Afrogenin
C00049578	Proceragenin

Human Protein / Gene in interactions

40 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00032213 C00032469	1 / 0
Q06710	Paired box protein Pax-8	Unclassified protein	C00032213 C00032469	1 / 2
P04637	Cellular tumor antigen p53	Transcription Factor	C00032213 C00032469	7 / 37
Q16637	Survival motor neuron protein	Unclassified protein	C00032213 C00032469	4 / 1
Q99700	Ataxin-2	Unclassified protein	C00032213 C00032469	1 / 1
P02545	Prelamin-A/C	Unclassified protein	C00032213 C00032469	11 / 10
P16473	Thyrotropin receptor	Glycohormone receptor	C00032213 C00032469	3 / 2
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00032213 C00032469	0 / 1
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00032213 C00032469	1 / 0
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00032213 C00032469	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00032213 C00032469	2 / 0
O75496	Geminin	Unclassified protein	C00032213 C00032469	0 / 0
P51151	Ras-related protein Rab-9A	Unclassified protein	C00032213 C00032469	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00032213 C00032469	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00032213 C00032469	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00032213 C00032469	0 / 1
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00032213 C00032469	1 / 1
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00032213 C00032469	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00032213 C00032469	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00032213 C00032469	0 / 0
O15118	Niemann-Pick C1 protein	Unclassified protein	C00032213 C00032469	1 / 1
P11308	Transcriptional regulator ERG	Unclassified protein	C00032213	1 / 2
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00032213	7 / 3
P54707	Potassium-transporting ATPase alpha chain 2	Potassium-transporting P-type ATPase alpha subunit	C00032469	0 / 0
P38398	Breast cancer type 1 susceptibility protein	Enzyme	C00032213	4 / 2
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00032213	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00032469	0 / 0
O60755	Galanin receptor type 3	Galanin receptor	C00032213	0 / 0
O00255	Menin	Unclassified protein	C00032213	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00032213	1 / 2
Q6ZQN7	Solute carrier organic anion transporter family member 4C1	Unclassified protein	C00032469	0 / 0
P05023	Sodium/potassium-transporting ATPase subunit alpha-1	Hydrolase	C00032469	0 / 0
P14415	Sodium/potassium-transporting ATPase subunit beta-2	potassium_sodium	C00032469	0 / 0
P13637	Sodium/potassium-transporting ATPase subunit alpha-3	Hydrolase	C00032469	2 / 1
Q13733	Sodium/potassium-transporting ATPase subunit alpha-4	Hydrolase	C00032469	0 / 0
P54710	Sodium/potassium-transporting ATPase subunit gamma	potassium_sodium	C00032469	1 / 1
P54709	Sodium/potassium-transporting ATPase subunit beta-3	potassium_sodium	C00032469	0 / 0
P50993	Sodium/potassium-transporting ATPase subunit alpha-2	Hydrolase	C00032469	2 / 2
P05026	Sodium/potassium-transporting ATPase subunit beta-1	potassium_sodium	C00032469	0 / 0
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00032469	3 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions