PCIDB

phytochemical cluster No. 56 (104 metabolites)

KCF-S cluster (6)

KCF-S ID # of metabolite
No. 109 46
No. 272 25
No. 468 17
No. 822 11
No. 4255 3
No. 4541 2

Metabolite list (104)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		figure
C00003599 External link 512 Bipindoside
No. 109
C00003600 External link 512 Lokundjoside
No. 109
C00003601 External link 512 Sarmentoloside
No. 109
C00003602 External link 512 Antioside
No. 109
C00038705 External link 512 Coroglaucigenin
CHEMBL495179
No. 109
C00003604 External link 512 Antiarigenin-3-O-beta-D-6-deoxy-alloside
CHEMBL1169680
CHEMBL1169681
CHEMBL1169683
No. 109
C00003605 External link 512 alpha-Antiarin
CHEMBL1169680
CHEMBL1169681
CHEMBL1169683
No. 109
C00038704 External link 512 12-Dehydroxyghalakinoside
/ (+)-12-Dehydroxyghalakinoside
No. 109
C00038703 External link 512 Ghalakinoside
CHEMBL499134
C062787
No. 109
C00038702 External link 512 6'-Dehydroxyghalakinoside
/ (+)-6'-Dehydroxyghalakinoside
CHEMBL469426
No. 109
C00003611 External link 512 Convallatoxin
CHEMBL249260
CHEMBL399336
CHEMBL1169848
CHEMBL1169675
CHEMBL1360620
CHEMBL1979962
C000505
3 / 11 / 38 No. 109
C00003612 External link 512 Strophanthojavoside
CHEMBL1172581
No. 109
C00003613 External link 512 Strophanolloside
CHEMBL1170234
No. 109
C00029698 External link 512 Musaroside
No. 109
C00038263 External link 512 Calactin
CHEMBL502127
CHEMBL495949
CHEMBL1992249
No. 109
C00038262 External link 512 15beta-Hydroxycalactin
CHEMBL448177
CHEMBL505598
No. 109
C00035559 External link 512 16alpha-Acetoxycalactin
CHEMBL448662
No. 109
C00035466 External link 512 Digitoxin
CHEMBL267817
CHEMBL254219
CHEMBL1324812
CHEMBL1899295
D004074
124 / 85 / 86 22 / 43 No. 109
C00003619 External link 512 Rhodexin A
No. 109
C00003620 External link 512 Adonitoxin
C013392
No. 109
C00034117 External link 512 Gitoxin
CHEMBL109317
CHEMBL137281
CHEMBL2069121
C005003
15 / 29 / 19 No. 109
C00032985 External link 512 Cryptostigmin I
No. 109
C00003625 External link 512 Cymarin
CHEMBL1555401
CHEMBL1983965
D003529
3 / 11 / 38 1 / 0 No. 109
C00032285 External link 512 Digitalin
/ Digitalinum verum
/ Schmiedeberg's digitalin
CHEMBL505674
C034791
0 / 1 No. 109
C00032215 External link 512 Cryptostigmin III
/ (-)-Cryptostigmin III
No. 109
C00003630 External link 512 Holarosine A
No. 109
C00003631 External link 512 Holarosine B
No. 109
C00003632 External link 512 N-Demethylmitiphylline
No. 109
C00003633 External link 512 Mitiphylline
No. 109
C00003634 External link 512 Cardenolide N-1
/ (-)-Cardenolide N-1
CHEMBL229533
CHEMBL229259
CHEMBL1993326
No. 109
C00003635 External link 512 17alpha-Neriifolin
CHEMBL504196
CHEMBL501533
CHEMBL1078503
CHEMBL1355522
CHEMBL1970197
CHEMBL1994861
5 / 26 / 50 No. 109
C00032212 External link 512 Cheiranthoside IV
/ (+)-Cheiranthoside IV
No. 109
C00032211 External link 512 Boivinide F
CHEMBL398874
No. 109
C00031724 External link 512 Boivinide E
No. 109
C00003641 External link 512 Cerberin
CHEMBL554969
C006951
No. 109
C00025509 External link 512 Cardenolide N-4
CHEMBL229258
CHEMBL413068
CHEMBL1162954
No. 109
C00025510 External link 512 Cerbertin
No. 109
C00025520 External link 512 Tanghinin
C069007
No. 109
C00025524 External link 512 Deacetyltanghinin
No. 109
C00031660 External link 512 Cheiranthoside X
No. 109
C00031547 External link 512 Boivinide C
No. 109
C00030416 External link 512 Periplocin
No. 109
C00030102 External link 512 3'-O-beta-D-glucopyranosylcalactin
/ (+)-3'-O-beta-D-glucopyranosylcalactin
CHEMBL508988
CHEMBL555674
No. 109
C00029899 External link 512 Boivinide D
CHEMBL249844
No. 109
C00029699 External link 512 Boivinide B
CHEMBL398881
CHEMBL251691
No. 109
C00038264 External link 512 Calotropin
CHEMBL502127
CHEMBL495949
CHEMBL1992249
No. 109
C00036960 External link 512 15beta-Hydroxycalotropin
CHEMBL448177
CHEMBL505598
No. 272
C00041275 External link 512 Uzarigenin 3-O-sulfate
/ (+)-Uzarigenin 3-O-sulfate
No. 272
C00040917 External link 512 Xysmalogenin
/ 5,6-Dehydrouzarigenin
No. 272
C00040916 External link 512 Strophanthidol
CHEMBL1628279
No. 272
C00003610 External link 512 Strophalloside
CHEMBL249260
CHEMBL399336
CHEMBL1169848
CHEMBL1169675
CHEMBL1360620
CHEMBL1979962
3 / 11 / 38 No. 272
C00038617 External link 512 16alpha-Acetoxyasclepin
CHEMBL454779
No. 272
C00038616 External link 512 19-nor-16alpha-Acetoxy-10beta-hydroxyasclepin
No. 272
C00038615 External link 512 Calactinic acid methyl ester
CHEMBL499114
No. 272
C00003639 External link 512 Divaricoside
C038190
No. 272
C00003638 External link 512 Neriifolin
/ 17beta-Neriifolin
CHEMBL504196
CHEMBL501533
CHEMBL1078503
CHEMBL1355522
CHEMBL1970197
CHEMBL1994861
C040684
5 / 26 / 50 No. 272
C00038614 External link 512 Uscharidin
CHEMBL449207
No. 272
C00038613 External link 512 Uscharin
CHEMBL500585
No. 272
C00038612 External link 512 16alpha-Hydroxyuscharin
No. 272
C00003615 External link 512 3-O-beta-D-Xylopyranosylperiplogenin
CHEMBL249248
No. 272
C00003616 External link 512 3-O-beta-D-Xylopyranosylstrophanthidin
CHEMBL249081
No. 272
C00036959 External link 512 Asclepin
CHEMBL445086
C020214
No. 272
C00036958 External link 512 16alpha-Hydroxyasclepin
CHEMBL471686
No. 272
C00032810 External link 512 Cheiranthoside V
/ (+)-Cheiranthoside V
No. 272
C00032811 External link 512 K-strophanthoside
CHEMBL447086
C008240
No. 272
C00003622 External link 512 Vernadigin
No. 272
C00036957 External link 512 16alpha-Acetoxycalotropin
CHEMBL448662
No. 272
C00034104 External link 512 Diginatin
CHEMBL112842
No. 272
C00034109 External link 512 Digoxin
CHEMBL1751
CHEMBL1477182
CHEMBL1512361
D004077
139 / 97 / 93 15 / 106 No. 272
C00003617 External link 512 Cannogenol-3-O-alpha-L-rhamnoside
/ 3-O-alpha-L-Rhamnopyranosylcannogenol
CHEMBL400877
C025779
No. 272
C00003618 External link 512 Frugoside
CHEMBL400877
C025778
No. 272
C00029413 External link 512 Cerleaside A
No. 468
C00003603 External link 512 Ouabain
CHEMBL222863
CHEMBL1320401
CHEMBL1493751
CHEMBL1512393
CHEMBL1524156
CHEMBL1591556
CHEMBL1617838
CHEMBL1720907
CHEMBL2069120
D010042
120 / 82 / 78 83 / 33 No. 468
C00042053 External link 512 Labriformin
CHEMBL1999973
No. 468
C00041540 External link 512 Labriformidin
No. 468
C00041405 External link 512 Eriocarpin
No. 468
C00032466 External link 512 Periforoside I
/ (+)-Periforoside I
No. 468
C00041285 External link 512 Corotoxigenin 3-O-sulfate
/ (+)-Corotoxigenin 3-O-sulfate
No. 468
C00029406 External link 512 2'-O-Acetylcerleaside A
No. 468
C00041246 External link 512 Coroglaucigenin 3-O-sulfate
/ (+)-Coroglaucigenin 3-O-sulfate
No. 468
C00041238 External link 512 Periforgenin A
No. 468
C00029405 External link 512 Cardenolide N-3
/ (+)-Cardenolide N-3
CHEMBL229203
No. 468
C00003640 External link 512 Divostroside
No. 468
C00029402 External link 512 Aspecioside
No. 468
C00029403 External link 512 Cardenolide N-2
/ (+)-Cardenolide N-2
CHEMBL375720
No. 468
C00029404 External link 512 Adynerin
CHEMBL375720
No. 468
C00003609 External link 512 Deglucocheirotoxin
CHEMBL249260
CHEMBL399336
CHEMBL1169848
CHEMBL1169675
CHEMBL1360620
CHEMBL1979962
C016114
3 / 11 / 38 No. 468
C00003608 External link 512 Antiarojavoside
/ 12beta-Hydroxystrophanthojavoside
CHEMBL1169682
No. 468
C00034103 External link 512 Cryptostigmin IV
No. 822
C00038847 External link 512 Uzarigenin
CHEMBL21214
CHEMBL1453
CHEMBL1591205
33 / 41 / 58 No. 822
C00038848 External link 512 Proceragenin
No. 822
C00042202 External link 512 Elaeodendroside U
/ (-)-Elaeodendroside U
CHEMBL376168
No. 822
C00040609 External link 512 Strophanthidin
/ Strophanthidine
/ Strophanthidin K
CHEMBL111743
CHEMBL368773
CHEMBL1437139
CHEMBL1516802
D013327
28 / 48 / 65 0 / 1 No. 822
C00032213 External link 512 Cheiranthoside IX
CHEMBL1169677
No. 822
C00030013 External link 512 Boivinide A
CHEMBL400632
No. 822
C00032214 External link 512 Cryptostigmin II
No. 822
C00032469 External link 512 Cerberoside
CHEMBL263601
No. 822
C00032536 External link 512 Thevetin A
No. 822
C00049578 External link 512 Decoside
No. 822
C00003621 External link 512 Gofruside
CHEMBL1169679
No. 4255
C00003626 External link 512 Helveticoside
CHEMBL1551151
C007914
11 / 18 / 15 No. 4255
C00003627 External link 512 Periplocymarin
/ (+)-Periplocymarin
CHEMBL502236
No. 4255
C00039103 External link 512 Afrogenin
No. 4541
C00003614 External link 512 3-O-beta-D-quinovopyranosylstrophanthidin
CHEMBL400356
CHEMBL400876
CHEMBL1169846
CHEMBL1169855
No. 4541

Human Protein / Gene in interactions

164 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q16637 Survival motor neuron protein Unclassified protein C00003612 C00003613 C00003617 C00003618 C00003622 C00003625 C00003632 C00003633 C00030102 C00032211 C00032213 C00032469 C00035466 4 / 1
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00003612 C00003613 C00003617 C00003618 C00003622 C00003632 C00003633 C00030102 C00032211 C00032213 C00032469 C00035466 0 / 0
P04637 Cellular tumor antigen p53 Transcription Factor C00003612 C00003613 C00003617 C00003618 C00003632 C00003633 C00030102 C00032211 C00032213 C00032469 C00035466 7 / 37
P02545 Prelamin-A/C Unclassified protein C00003617 C00003618 C00003622 C00003625 C00003632 C00003633 C00032213 C00032469 C00035466 11 / 10
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00003617 C00003618 C00003622 C00003633 C00032213 C00032469 1 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00003617 C00003618 C00003622 C00003633 C00032213 C00032469 0 / 0
Q99700 Ataxin-2 Unclassified protein C00003618 C00003622 C00003625 C00003633 C00032213 C00032469 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00003617 C00003618 C00003625 C00003633 C00032213 C00032469 0 / 1
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00003617 C00003618 C00003625 C00003633 C00032213 C00032469 1 / 1
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00003617 C00003618 C00003625 C00003633 C00032213 C00032469 1 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00003617 C00003618 C00003625 C00003633 C00032213 C00032469 0 / 1
O75496 Geminin Unclassified protein C00003617 C00003618 C00003622 C00003633 C00032213 C00032469 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00003617 C00003618 C00003622 C00003633 C00032213 C00032469 2 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00003617 C00003618 C00003625 C00003633 C00032213 C00032469 0 / 0
P51151 Ras-related protein Rab-9A Unclassified protein C00003617 C00003618 C00003633 C00032213 C00032469 0 / 0
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor C00003618 C00003625 C00003633 C00032213 C00032469 0 / 0
O15118 Niemann-Pick C1 protein Unclassified protein C00003617 C00003618 C00003633 C00032213 C00032469 1 / 1
P16473 Thyrotropin receptor Glycohormone receptor C00003618 C00003633 C00032213 C00032469 3 / 2
Q6ZQN7 Solute carrier organic anion transporter family member 4C1 Unclassified protein C00003617 C00003618 C00003633 C00032469 0 / 0
P35372 Mu-type opioid receptor Opioid receptor C00003617 C00003618 C00003633 0 / 0
Q06710 Paired box protein Pax-8 Unclassified protein C00003618 C00032213 C00032469 1 / 2
P14780 Matrix metalloproteinase-9 M10A C00003617 C00003618 C00003633 2 / 2
P05026 Sodium/potassium-transporting ATPase subunit beta-1 potassium_sodium C00003617 C00003618 C00032469 0 / 0
P50993 Sodium/potassium-transporting ATPase subunit alpha-2 Hydrolase C00003617 C00003618 C00032469 2 / 2
P17252 Protein kinase C alpha type Alpha C00003617 C00003618 C00003633 0 / 0
P54709 Sodium/potassium-transporting ATPase subunit beta-3 potassium_sodium C00003617 C00003618 C00032469 0 / 0
P29466 Caspase-1 C14 C00003617 C00003618 C00003633 0 / 0
P54710 Sodium/potassium-transporting ATPase subunit gamma potassium_sodium C00003617 C00003618 C00032469 1 / 1
Q13733 Sodium/potassium-transporting ATPase subunit alpha-4 Hydrolase C00003617 C00003618 C00032469 0 / 0
P00918 Carbonic anhydrase 2 Lyase C00003617 C00003618 C00003633 1 / 2
P07550 Beta-2 adrenergic receptor Adrenergic receptor C00003617 C00003618 C00003633 0 / 1
P21397 Amine oxidase [flavin-containing] A Oxidoreductase C00003617 C00003618 C00003633 1 / 1
P25021 Histamine H2 receptor Histamine receptor C00003617 C00003618 C00003633 0 / 0
P35367 Histamine H1 receptor Histamine receptor C00003617 C00003618 C00003633 0 / 0
Q01959 Sodium-dependent dopamine transporter Dopamine C00003617 C00003618 C00003633 1 / 0
P08912 Muscarinic acetylcholine receptor M5 Acetylcholine receptor C00003617 C00003618 C00003633 0 / 0
P18825 Alpha-2C adrenergic receptor Adrenergic receptor C00003617 C00003618 C00003633 0 / 0
P13945 Beta-3 adrenergic receptor Adrenergic receptor C00003617 C00003618 C00003633 0 / 0
P13637 Sodium/potassium-transporting ATPase subunit alpha-3 Hydrolase C00003617 C00003618 C00032469 2 / 1
P14415 Sodium/potassium-transporting ATPase subunit beta-2 potassium_sodium C00003617 C00003618 C00032469 0 / 0
P25024 C-X-C chemokine receptor type 1 CXC chemokine receptor C00003617 C00003618 C00003633 0 / 0
P06241 Tyrosine-protein kinase Fyn Src C00003617 C00003618 C00003633 0 / 0
Q08209 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform Ser_Thr C00003617 C00003618 C00003633 0 / 0
P49146 Neuropeptide Y receptor type 2 Neuropeptide Y receptor C00003617 C00003618 C00003633 0 / 0
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily C00003617 C00003618 C00003633 1 / 8
P05023 Sodium/potassium-transporting ATPase subunit alpha-1 Hydrolase C00003617 C00003618 C00032469 0 / 0
P42224 Signal transducer and activator of transcription 1-alpha/beta Unclassified protein C00003617 C00003618 C00003633 3 / 3
P14416 D(2) dopamine receptor Dopamine receptor C00003617 C00003618 C00003633 2 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00003617 C00003618 C00003633 0 / 0
P37288 Vasopressin V1a receptor Vasopressin and oxytocin receptor C00003617 C00003618 C00003633 0 / 0
P41145 Kappa-type opioid receptor Opioid receptor C00003617 C00003618 C00003633 0 / 0
Q9Y271 Cysteinyl leukotriene receptor 1 Leukotriene receptor C00003617 C00003618 C00003633 0 / 0
P29274 Adenosine receptor A2a Adenosine receptor C00003617 C00003618 C00003633 0 / 0
P25929 Neuropeptide Y receptor type 1 Neuropeptide Y receptor C00003617 C00003618 C00003633 0 / 0
P50052 Type-2 angiotensin II receptor Angiotensin receptor C00003617 C00003618 C00003633 1 / 1
P17948 Vascular endothelial growth factor receptor 1 Vegfr C00003617 C00003618 C00003633 0 / 0
P41968 Melanocortin receptor 3 Melanocortin receptor C00003617 C00003618 C00003633 1 / 0
P25025 C-X-C chemokine receptor type 2 CXC chemokine receptor C00003617 C00003618 C00003633 0 / 0
P68871 Hemoglobin subunit beta Secreted protein C00003622 C00003632 C00035466 4 / 4
P06239 Tyrosine-protein kinase Lck Src C00003617 C00003618 C00003633 0 / 1
P11509 Cytochrome P450 2A6 Cytochrome P450 2A6 C00003617 C00003618 C00003633 0 / 0
Q16539 Mitogen-activated protein kinase 14 p38 C00003617 C00003618 C00003633 0 / 0
P24557 Thromboxane-A synthase Cytochrome P450 5A1 C00003617 C00003618 C00003633 1 / 1
P33765 Adenosine receptor A3 Adenosine receptor C00003617 C00003618 C00003633 0 / 0
P08246 Neutrophil elastase S1A C00003617 C00003618 C00003633 2 / 1
P18089 Alpha-2B adrenergic receptor Adrenergic receptor C00003617 C00003618 C00003633 0 / 0
P30542 Adenosine receptor A1 Adenosine receptor C00003617 C00003618 C00003633 0 / 0
P25100 Alpha-1D adrenergic receptor Adrenergic receptor C00003617 C00003618 C00003633 0 / 0
P23975 Sodium-dependent noradrenaline transporter Norepinephrine C00003617 C00003618 C00003633 1 / 1
P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase Oxidoreductase C00003617 C00003618 C00003633 0 / 0
P08913 Alpha-2A adrenergic receptor Adrenergic receptor C00003617 C00003618 C00003633 0 / 0
P21917 D(4) dopamine receptor Dopamine receptor C00003617 C00003618 C00003633 0 / 0
P30988 Calcitonin receptor Calcitonin receptor C00003617 C00003618 C00003633 0 / 0
P35462 D(3) dopamine receptor Dopamine receptor C00003617 C00003618 C00003633 1 / 0
P41143 Delta-type opioid receptor Opioid receptor C00003617 C00003618 C00003633 0 / 0
Q92731 Estrogen receptor beta NR3A2 C00003617 C00003618 C00003633 0 / 1
P41595 5-hydroxytryptamine receptor 2B Serotonin receptor C00003617 C00003618 C00003633 0 / 0
P25101 Endothelin-1 receptor Endothelin receptor C00003617 C00003618 C00003633 0 / 0
P30411 B2 bradykinin receptor Bradykinin receptor C00003617 C00003618 C00003633 0 / 0
P05181 Cytochrome P450 2E1 Cytochrome P450 2E1 C00003617 C00003618 C00003633 0 / 0
P32245 Melanocortin receptor 4 Melanocortin receptor C00003617 C00003618 C00003633 1 / 0
P32238 Cholecystokinin receptor type A Cholecystokinin receptor C00003617 C00003618 C00003633 0 / 0
P08311 Cathepsin G S1A C00003617 C00003618 C00003633 0 / 0
Q99720 Sigma non-opioid intracellular receptor 1 Membrane receptor C00003617 C00003618 C00003633 1 / 0
P40763 Signal transducer and activator of transcription 3 Transcription Factor C00003617 C00003618 C00003633 1 / 2
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00003622 C00032213 C00032469 0 / 0
P03956 Interstitial collagenase M10A C00003617 C00003618 C00003633 0 / 1
P21728 D(1A) dopamine receptor Dopamine receptor C00003617 C00003618 C00003633 0 / 0
P32241 Vasoactive intestinal polypeptide receptor 1 Vasoactive intestinal peptide receptor C00003617 C00003618 C00003633 0 / 0
P33032 Melanocortin receptor 5 Melanocortin receptor C00003617 C00003618 C00003633 0 / 0
P25105 Platelet-activating factor receptor PAF receptor C00003617 C00003618 C00003633 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00003622 C00032213 C00032469 0 / 0
P25103 Substance-P receptor Neurokinin receptor C00003617 C00003618 C00003633 0 / 0
P04150 Glucocorticoid receptor NR3C1 C00003617 C00003618 C00003633 0 / 1
P08172 Muscarinic acetylcholine receptor M2 Acetylcholine receptor C00003617 C00003618 C00003633 2 / 0
P11229 Muscarinic acetylcholine receptor M1 Acetylcholine receptor C00003617 C00003618 C00003633 0 / 0
P21554 Cannabinoid receptor 1 Cannabinoid receptor C00003617 C00003618 C00003633 0 / 0
P31645 Sodium-dependent serotonin transporter Serotonin C00003617 C00003618 C00003633 2 / 0
P08173 Muscarinic acetylcholine receptor M4 Acetylcholine receptor C00003617 C00003618 C00003633 0 / 0
P04626 Receptor tyrosine-protein kinase erbB-2 TK tyrosine-protein kinase EGFR subfamily C00003617 C00003618 C00003633 5 / 9
P20309 Muscarinic acetylcholine receptor M3 Acetylcholine receptor C00003617 C00003618 C00003633 1 / 0
P21452 Substance-K receptor Neurokinin receptor C00003617 C00003618 C00003633 0 / 0
P51679 C-C chemokine receptor type 4 CC chemokine receptor C00003617 C00003618 C00003633 0 / 0
P51681 C-C chemokine receptor type 5 CC chemokine receptor C00003617 C00003618 C00003633 3 / 0
P50406 5-hydroxytryptamine receptor 6 Serotonin receptor C00003617 C00003618 C00003633 0 / 0
P27361 Mitogen-activated protein kinase 3 Erk C00003617 C00003618 C00003633 0 / 0
P28335 5-hydroxytryptamine receptor 2C Serotonin receptor C00003617 C00003618 C00003633 0 / 0
P41597 C-C chemokine receptor type 2 CC chemokine receptor C00003617 C00003618 C00003633 1 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00003617 C00003618 C00003633 0 / 0
P08575 Receptor-type tyrosine-protein phosphatase C Enzyme C00003617 C00003618 C00003633 2 / 1
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) C00003617 C00003618 C00003633 2 / 2
P28223 5-hydroxytryptamine receptor 2A Serotonin receptor C00003617 C00003618 C00003633 0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00003617 C00003618 C00003633 0 / 3
P22303 Acetylcholinesterase Hydrolase C00003617 C00003618 C00003633 1 / 0
P08588 Beta-1 adrenergic receptor Adrenergic receptor C00003617 C00003618 C00003633 1 / 0
P03372 Estrogen receptor NR3A1 C00003617 C00003618 C00003633 1 / 1
O76074 cGMP-specific 3',5'-cyclic phosphodiesterase PDE_5A C00003617 C00003618 C00003633 0 / 0
Q9NPD5 Solute carrier organic anion transporter family member 1B3 Electrochemical transporter C00003618 C00003633 1 / 0
P27338 Amine oxidase [flavin-containing] B Oxidoreductase C00003617 C00003618 0 / 0
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 C00003617 C00003618 0 / 0
O75604 Ubiquitin carboxyl-terminal hydrolase 2 Enzyme C00003617 C00003622 0 / 0
P10828 Thyroid hormone receptor beta NR1A2 C00003617 C00003618 3 / 1
Q96RI1 Bile acid receptor NR1H4 C00003617 C00003618 0 / 0
P19793 Retinoic acid receptor RXR-alpha NR2B1 C00003617 C00003618 0 / 0
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 C00003617 C00003618 5 / 3
P02768 Serum albumin Secreted protein C00003617 C00003633 0 / 0
P08183 Multidrug resistance protein 1 drug C00003617 C00003618 1 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00003633 C00032213 7 / 3
Q9NYB5 Solute carrier organic anion transporter family member 1C1 Unclassified protein C00003618 C00003633 0 / 0
Q9Y6L6 Solute carrier organic anion transporter family member 1B1 Electrochemical transporter C00003618 C00003633 1 / 0
P54707 Potassium-transporting ATPase alpha chain 2 Potassium-transporting P-type ATPase alpha subunit C00003633 C00032469 0 / 0
P49798 Regulator of G-protein signaling 4 Unclassified protein C00003618 C00003622 2 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00003633 C00032469 0 / 0
P11473 Vitamin D3 receptor NR1I1 C00003617 C00003618 2 / 3
P10636 Microtubule-associated protein tau Unclassified protein C00003617 C00003622 4 / 3
O94956 Solute carrier organic anion transporter family member 2B1 Unclassified protein C00003618 C00003633 0 / 0
P10275 Androgen receptor NR3C4 C00003617 C00003618 3 / 4
P00352 Retinal dehydrogenase 1 Enzyme C00003622 C00003625 0 / 0
P46721 Solute carrier organic anion transporter family member 1A2 Unclassified protein C00003618 C00003633 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00003625 C00003633 0 / 0
P01375 Tumor necrosis factor Secreted protein C00003618 3 / 4
Q8TCC7 Solute carrier family 22 member 8 Antiporter C00003633 0 / 0
O60755 Galanin receptor type 3 Galanin receptor C00032213 0 / 0
P31939 Bifunctional purine biosynthesis protein PURH Enzyme C00003633 1 / 1
P38398 Breast cancer type 1 susceptibility protein Enzyme C00032213 4 / 2
B2RXH2 Lysine-specific demethylase 4E Enzyme C00032213 0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme C00003618 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00003618 0 / 0
P10145 Interleukin-8 Secreted protein C00003618 0 / 0
Q02880 DNA topoisomerase 2-beta Isomerase C00003617 0 / 0
O00255 Menin Unclassified protein C00032213 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00032213 1 / 2
P22310 UDP-glucuronosyltransferase 1-4 Enzyme C00032469 3 / 0
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor C00003633 0 / 0
Q86UW1 Organic solute transporter subunit alpha Unclassified protein C00003618 0 / 0
P11388 DNA topoisomerase 2-alpha Isomerase C00003617 0 / 0
P11308 Transcriptional regulator ERG Unclassified protein C00032213 1 / 2
P21439 Multidrug resistance protein 3 Enzyme C00003618 3 / 2
P06280 Alpha-galactosidase A Enzyme C00003618 1 / 1
Q92887 Canalicular multispecific organic anion transporter 1 Unclassified protein C00003618 1 / 1
A2TJX0 Krueppel-like factor 5 Unclassified protein C00003633 0 / 0
Q01453 Peripheral myelin protein 22 Unclassified protein C00003633 5 / 2
O15245 Solute carrier family 22 member 1 Drug uniporter C00003618 0 / 0
P51449 Nuclear receptor ROR-gamma Nuclear hormone receptor subfamily 1 group F member 3 C00003618 0 / 0

112 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
5243 ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) C00003613 C00003617 C00003618 C00003633
3091 HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) C00003618 C00003633
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00003617 C00003633
3757 KCNH2, ERG1, HERG, HERG1, Kv11.1, LQT2, SQT1 potassium voltage-gated channel, subfamily H (eag-related), member 2 C00003618 C00003633
3576 IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 interleukin 8 C00003617 C00003618
6347 CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF chemokine (C-C motif) ligand 2 C00003617 C00003618
1026 CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 cyclin-dependent kinase inhibitor 1A (p21, Cip1) C00003617 C00003633
4047 LSS, OSC lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) (EC:5.4.99.7) C00003633
891 CCNB1, CCNB cyclin B1 C00003617
1027 CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1 cyclin-dependent kinase inhibitor 1B (p27, Kip1) C00003617
1111 CHEK1, CHK1 checkpoint kinase 1 (EC:2.7.11.1) C00003617
11200 CHEK2, CDS1, CHK2, HuCds1, LFS2, PP1425, RAD53, hCds1 checkpoint kinase 2 (EC:2.7.11.1) C00003617
54205 CYCS, CYC, HCS, THC4 cytochrome c, somatic C00003617
3553 IL1B, IL-1, IL1-BETA, IL1F2 interleukin 1, beta C00003617
842 CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) C00003617
5594 MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk mitogen-activated protein kinase 1 (EC:2.7.11.24) C00003617
5595 MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK mitogen-activated protein kinase 3 (EC:2.7.11.24) C00003617
4790 NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 C00003617
4792 NFKBIA, IKBA, MAD-3, NFKBI nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha C00003617
4846 NOS3, ECNOS, eNOS nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) C00003617
7157 TP53, BCC7, LFS1, P53, TRP53 tumor protein p53 C00003617
7412 VCAM1, CD106, INCAM-100 vascular cell adhesion molecule 1 C00003617
10351 ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 C00003618
9429 ABCG2, ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1 ATP-binding cassette, sub-family G (WHITE), member 2 C00003618
6351 CCL4, ACT2, AT744.1, G-26, HC21, LAG-1, LAG1, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4 chemokine (C-C motif) ligand 4 C00003618
6352 CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP chemokine (C-C motif) ligand 5 C00003618
841 CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) C00003617
3570 IL6R, CD126, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ, gp80 interleukin 6 receptor C00003618
3630 INS, IDDM2, ILPR, IRDN, MODY10 insulin C00003618
332 BIRC5, API4, EPR-1 baculoviral IAP repeat containing 5 C00003617
4879 NPPB, BNP natriuretic peptide B C00003618
6580 SLC22A1, HOCT1, OCT1, oct1_cds solute carrier family 22 (organic cation transporter), member 1 C00003618
6581 SLC22A3, EMT, EMTH, OCT3 solute carrier family 22 (organic cation transporter), member 3 C00003618
7422 VEGFA, MVCD1, VEGF, VPF vascular endothelial growth factor A C00003618
2 A2M, A2MD, CPAMD5, FWP007, S863-7 alpha-2-macroglobulin C00003633
10449 ACAA2, DSAEC acetyl-CoA acyltransferase 2 (EC:2.3.1.16) C00003633
59 ACTA2, AAT6, ACTSA, MYMY5 actin, alpha 2, smooth muscle, aorta C00003633
126 ADH1C, ADH3 alcohol dehydrogenase 1C (class I), gamma polypeptide (EC:1.1.1.1) C00003633
301 ANXA1, ANX1, LPC1 annexin A1 C00003633
302 ANXA2, ANX2, ANX2L4, CAL1H, LIP2, LPC2, LPC2D, P36, PAP-IV annexin A2 C00003633
369 ARAF, A-RAF, ARAF1, PKS2, RAFA1 v-raf murine sarcoma 3611 viral oncogene homolog (EC:2.7.11.1) C00003633
25820 ARIH1, ARI, HARI, HHARI, UBCH7BP ariadne RBR E3 ubiquitin protein ligase 1 C00003633
10092 ARPC5, ARC16, dJ127C7.3, p16-Arc actin related protein 2/3 complex, subunit 5, 16kDa C00003633
408 ARRB1, ARB1, ARR1 arrestin, beta 1 C00003633
427 ASAH1, AC, ACDase, ASAH, PHP, PHP32, SMAPME N-acylsphingosine amidohydrolase (acid ceramidase) 1 (EC:3.5.1.23) C00003633
479 ATP12A, ATP1AL1 ATPase, H+/K+ transporting, nongastric, alpha polypeptide (EC:3.6.3.10) C00003633
476 ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide (EC:3.6.3.9) C00003633
477 ATP1A2, FHM2, MHP2 ATPase, Na+/K+ transporting, alpha 2 polypeptide (EC:3.6.3.9) C00003633
478 ATP1A3, AHC2, DYT12, RDP ATPase, Na+/K+ transporting, alpha 3 polypeptide (EC:3.6.3.9) C00003633
496 ATP4B, ATP6B ATPase, H+/K+ exchanging, beta polypeptide C00003633
498 ATP5A1, ATP5A, ATP5AL2, ATPM, MC5DN4, MOM2, OMR, ORM, hATP1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle C00003633
22893 BAHD1 bromo adjacent homology domain containing 1 C00003633
581 BAX, BCL2L4 BCL2-associated X protein C00003633
51806 CALML5, CLSP calmodulin-like 5 C00003633
821 CANX, CNX, IP90, P90 calnexin C00003633
64770 CCDC14 coiled-coil domain containing 14 C00003633
8900 CCNA1 cyclin A1 C00003633
890 CCNA2, CCN1, CCNA cyclin A2 C00003633
1017 CDK2, p33(CDK2) cyclin-dependent kinase 2 (EC:2.7.11.22) C00003633
9076 CLDN1, CLD1, ILVASC, SEMP1 claudin 1 C00003633
10330 CNPY2, HP10390, MSAP, TMEM4, ZSIG9 canopy FGF signaling regulator 2 C00003633
1537 CYC1, MC3DN6, UQCR4 cytochrome c-1 C00003633
1650 DDOST, AGER1, CDG1R, OKSWcl45, OST, OST48, WBP1 dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) (EC:2.4.99.18) C00003633
1812 DRD1, DADR, DRD1A dopamine receptor D1 C00003633
1828 DSG1, CDHF4, DG1, DSG, EPKHIA, PPKS1, SPPK1 desmoglein 1 C00003633
1854 DUT, dUTPase deoxyuridine triphosphatase (EC:3.6.1.23) C00003633
1889 ECE1, ECE endothelin converting enzyme 1 (EC:3.4.24.71) C00003633
1892 ECHS1, SCEH enoyl CoA hydratase, short chain, 1, mitochondrial (EC:4.2.1.17) C00003633
27335 EIF3K, EIF3-p28, EIF3S12, HSPC029, M9, MSTP001, PLAC-24, PLAC24, PRO1474, PTD001 eukaryotic translation initiation factor 3, subunit K C00003633
10667 FARS2, COXPD14, FARS1, HSPC320, PheRS, dJ520B18.2 phenylalanyl-tRNA synthetase 2, mitochondrial (EC:6.1.1.20) C00003633
2271 FH, HLRCC, LRCC, MCL, MCUL1 fumarate hydratase (EC:4.2.1.2) C00003633
51661 FKBP7, FKBP23, PPIase FK506 binding protein 7 (EC:5.2.1.8) C00003633
2638 GC, DBP, DBP/GC, GRD3, VDBG, VDBP group-specific component (vitamin D binding protein) (EC:6.4.-.-) C00003633
2743 GLRB, HKPX2 glycine receptor, beta C00003633
8225 GTPBP6, PGPL GTP binding protein 6 (putative) C00003633
3181 HNRNPA2B1, HNRNPA2, HNRNPB1, HNRPA2, HNRPA2B1, HNRPB1, IBMPFD2, RNPA2, SNRPB1 heterogeneous nuclear ribonucleoprotein A2/B1 C00003633
9987 HNRNPDL, HNRNP, HNRPDL, JKTBP, JKTBP2, laAUF1 heterogeneous nuclear ribonucleoprotein D-like C00003633
3241 HPCAL1, BDR1, HLP2, VILIP-3 hippocalcin-like 1 C00003633
3273 HRG, HPRG, HRGP, THPH11 histidine-rich glycoprotein C00003633
3329 HSPD1, CPN60, GROEL, HLD4, HSP-60, HSP60, HSP65, HuCHA60, SPG13 heat shock 60kDa protein 1 (chaperonin) C00003633
3559 IL2RA, CD25, IDDM10, IL2R, TCGFR interleukin 2 receptor, alpha C00003633
3560 IL2RB, CD122, IL15RB, P70-75 interleukin 2 receptor, beta C00003633
3751 KCND2, KV4.2, RK5 potassium voltage-gated channel, Shal-related subfamily, member 2 C00003633
3956 LGALS1, GAL1, GBP lectin, galactoside-binding, soluble, 1 C00003633
983 CDK1, CDC2, CDC28A, P34CDC2 cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) C00003617
5598 MAPK7, BMK1, ERK4, ERK5, PRKM7 mitogen-activated protein kinase 7 (EC:2.7.11.24) C00003633
4191 MDH2, M-MDH, MDH, MGC:3559, MOR1 malate dehydrogenase 2, NAD (mitochondrial) (EC:1.1.1.37) C00003633
4609 MYC, MRTL, MYCC, bHLHe39, c-Myc v-myc avian myelocytomatosis viral oncogene homolog C00003633
10627 MYL12A, MLCB, MRCL3, MRLC3, MYL2B myosin, light chain 12A, regulatory, non-sarcomeric C00003633
10577 NPC2, EDDM1, HE1 Niemann-Pick disease, type C2 C00003633
5111 PCNA proliferating cell nuclear antigen C00003633
10016 PDCD6, ALG-2, PEF1B programmed cell death 6 C00003633
5204 PFDN5, MM-1, MM1, PFD5 prefoldin subunit 5 C00003633
5216 PFN1, ALS18 profilin 1 C00003633
9374 PPT2, C6orf8, G14, PPT-2 palmitoyl-protein thioesterase 2 (EC:3.1.2.22) C00003633
5694 PSMB6, DELTA, LMPY, Y proteasome (prosome, macropain) subunit, beta type, 6 (EC:3.4.25.1) C00003633
5771 PTPN2, PTN2, PTPT, TC-PTP, TCELLPTP, TCPTP protein tyrosine phosphatase, non-receptor type 2 (EC:3.1.3.48) C00003633
9230 RAB11B, H-YPT3 RAB11B, member RAS oncogene family C00003633
6093 ROCK1, P160ROCK, ROCK-I Rho-associated, coiled-coil containing protein kinase 1 (EC:2.7.11.1) C00003633
9475 ROCK2, ROCK-II Rho-associated, coiled-coil containing protein kinase 2 (EC:2.7.11.1) C00003633
6119 RPA3, REPA3 replication protein A3, 14kDa C00003633
23322 RPGRIP1L, CORS3, FTM, JBTS7, MKS5, NPHP8 RPGRIP1-like C00003633
6284 S100A13 S100 calcium binding protein A13 C00003633
6446 SGK1, SGK serum/glucocorticoid regulated kinase 1 (EC:2.7.11.1) C00003633
10110 SGK2, H-SGK2, dJ138B7.2 serum/glucocorticoid regulated kinase 2 (EC:2.7.11.1) C00003633
23678 SGK3, CISK, SGK2, SGKL serum/glucocorticoid regulated kinase family, member 3 (EC:2.7.11.1) C00003633
6528 SLC5A5, NIS, TDH1 solute carrier family 5 (sodium/iodide cotransporter), member 5 C00003633
8884 SLC5A6, SMVT solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 C00003633
7167 TPI1, TIM, TPI, TPID triosephosphate isomerase 1 (EC:5.3.1.1) C00003633
7178 TPT1, HRF, TCTP, p02, p23 tumor protein, translationally-controlled 1 C00003633
7295 TXN, TRDX, TRX, TRX1 thioredoxin C00003633
463 ZFHX3, ATBF1, ATBT, ZNF927 zinc finger homeobox 3 C00003633

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (128)

OMIM preferred title UniProt
#100100 Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism P20309
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#608688 Aicar transformylase/imp cyclohydrolase deficiency P31939
#103780 Alcohol dependence P08172
P14416
P31645
#104290 Alternating hemiplegia of childhood 1; ahc1 P50993
#614820 Alternating hemiplegia of childhood 2; ahc2 P13637
#614373 Amyotrophic lateral sclerosis 16, juvenile; als16 Q99720
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#209950 Atypical mycobacteriosis, familial P42224
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#613985 Beta-thalassemia P68871
#603902 Beta-thalassemia, dominant inclusion body type P68871
#602025 Body mass index quantitative trait locus 9; bmiq9 P41968
%606641 Body mass index; bmi P37231
#114480 Breast cancer P38398
#604370 Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 P38398
#300615 Brunner syndrome P21397
#614162 Candidiasis, familial, 7; candf7 P42224
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#609338 Carotid intimal medial thickness 1 P37231
#118300 Charcot-marie-tooth disease and deafness Q01453
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#118220 Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a Q01453
#614972 Cholestasis, intrahepatic, of pregnancy 3; icp3 P21439
#602347 Cholestasis, progressive familial intrahepatic, 3; pfic3 P21439
#114500 Colorectal cancer; crc P84022
#218800 Crigler-najjar syndrome, type i P22310
#606785 Crigler-najjar syndrome, type ii P22310
#162800 Cyclic neutropenia P08246
#612522 Diabetes mellitus, insulin-dependent, 22; iddm22 P51681
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#237500 Dubin-johnson syndrome; djs Q92887
#128235 Dystonia 12; dyt12 P13637
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#133239 Esophageal cancer P04637
#615363 Estrogen resistance; estrr P03372
#612219 Ewing sarcoma; es P11308
#301500 Fabry disease P06280
#600274 Frontotemporal dementia; ftd P10636
#600803 Gallbladder disease 1; gbd1 P21439
#613659 Gastric cancer P04626
#137215 Gastric cancer, hereditary diffuse; hdgc P04626
#231095 Ghosal hematodiaphyseal dysplasia; ghdd P24557
#143500 Gilbert syndrome P22310
#137800 Glioma susceptibility 1; glm1 O75874
P04626
P37231
#139393 Guillain-barre syndrome, familial; gbs Q01453
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#140700 Heinz body anemias P68871
#610424 Hepatitis b virus, susceptibility to P01375
#609423 Human immunodeficiency virus type 1, susceptibility to P41597
P51681
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#147060 Hyper-ige recurrent infection syndrome, autosomal dominant P40763
#237450 Hyperbilirubinemia, rotor type; hblrr Q9NPD5
Q9Y6L6
#145000 Hyperparathyroidism 1; hrpt1 O00255
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#145900 Hypertrophic neuropathy of dejerine-sottas Q01453
#154020 Hypomagnesemia 2, renal; homg2 P54710
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#218700 Hypothyroidism, congenital, nongoitrous, 2; chng2 Q06710
#612244 Inflammatory bowel disease 13; ibd13 P08183
#603932 Intervertebral disc disease; idd P14780
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#613688 Long qt syndrome 2; lqt2 Q12809
#211980 Lung cancer P00533
P04626
P04637
#608516 Major depressive disorder; mdd P08172
#611162 Malaria, susceptibility to P01375
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#174800 Mccune-albright syndrome; mas P63092
%300852 Mental retardation, x-linked 88; mrx88 P50052
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#602481 Migraine, familial hemiplegic, 2; fhm2 P50993
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#126200 Multiple sclerosis, susceptibility to; ms P08575
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#613796 Mycobacterial and viral infections, susceptibility to, autosomal recessive P42224
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#159900 Myoclonic dystonia P14416
#162500 Neuropathy, hereditary, with liability to pressure palsies; hnpp Q01453
#202700 Neutropenia, severe congenital, 1, autosomal dominant; scn1 P08246
#257220 Niemann-pick disease, type c1; npc1 O15118
#601665 Obesity P32245
P37231
#164230 Obsessive-compulsive disorder; ocd P31645
#604715 Orthostatic intolerance P23975
#166350 Osseous heteroplasia, progressive; poh P63092
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#167000 Ovarian cancer P04626
P38398
#614320 Pancreatic cancer, susceptibility to, 4; pnca4 P38398
#260500 Papilloma of choroid plexus; cpp P04637
#260540 Parkinson-dementia syndrome P10636
#613135 Parkinsonism-dystonia, infantile; pkdys Q01959
#172700 Pick disease of brain P10636
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#607507 Psoriatic arthritis, susceptibility to P01375
#607276 Resting heart rate, variation in P08588
#275210 Restrictive dermopathy, lethal P02545
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#608971 Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive P08575
#609620 Short qt syndrome 1; sqt1 Q12809
#603903 Sickle cell anemia P68871
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#190300 Tremor, hereditary essential, 1; etm1 P35462
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#610379 West nile virus, susceptibility to P51681
#112100 Yt blood group antigen P22303

KEGG DISEASE (110)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
P04637 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00136 Niemann-Pick disease type C (NPC) O15118 (related)
H00016 Oral cancer P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
P40763 (related)
H00017 Esophageal cancer P00533 (related)
P04637 (related)
P04637 (marker)
P35354 (related)
H00018 Gastric cancer P00533 (related)
P04626 (related)
P04637 (related)
H00022 Bladder cancer P00533 (related)
P04626 (related)
P04637 (related)
P68871 (marker)
H00028 Choriocarcinoma P00533 (related)
P03956 (related)
P04626 (related)
P04637 (related)
H00030 Cervical cancer P00533 (related)
P04626 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00079 Asthma P01375 (related)
P07550 (related)
H00080 Systemic lupus erythematosus P01375 (related)
P01375 (marker)
H00083 Allograft rejection P01375 (related)
H00084 Graft-versus-host disease P01375 (related)
P01375 (marker)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
Q01453 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
P37231 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00026 Endometrial Cancer P03372 (marker)
P04626 (related)
P04637 (related)
Q92731 (marker)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00019 Pancreatic cancer P04626 (related)
P04637 (related)
P04637 (marker)
H00027 Ovarian cancer P04626 (related)
P04637 (related)
P38398 (related)
H00031 Breast cancer P04626 (related)
P04626 (marker)
P04637 (related)
P38398 (related)
H00046 Cholangiocarcinoma P04626 (related)
P04637 (related)
P35354 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
P68871 (marker)
H00025 Penile cancer P04637 (related)
P04637 (marker)
P14780 (related)
P35354 (related)
H00029 Vulvar cancer P04637 (related)
H00032 Thyroid cancer P04637 (related)
P37231 (related)
Q06710 (related)
H00036 Osteosarcoma P04637 (related)
P08684 (marker)
H00038 Malignant melanoma P04637 (related)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00044 Cancer of the anal canal P04637 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00021 Renal cell carcinoma P04637 (marker)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00125 Fabry disease P06280 (related)
H00100 Neutropenic disorders P08246 (related)
H00091 T-B+Severe combined immunodeficiencies (SCIDs) P08575 (related)
H00024 Prostate cancer P10275 (related)
P11308 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00035 Ewing's sarcoma P11308 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H01205 Coumarin resistance P11712 (related)
H00831 Primary dystonia P13637 (related)
H00479 Metaphyseal dysplasias P14780 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
Q06710 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00548 Brunner syndrome P21397 (related)
H00624 Familial cholestasis P21439 (related)
H01213 Gallbladder disease P21439 (related)
H01031 Orthostatic intolerance (OI) P23975 (related)
H00490 Diaphyseal dysplasia with anemia (Ghosal) P24557 (related)
H00966 AICA-ribosiduria P31939 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00107 Other well-defined immunodeficiency syndromes P40763 (related)
H00089 IFN-gamma/IL-12 axis P42224 (related)
H00363 Candidiasis P42224 (related)
H01109 Chronic mucocutaneous candidiasis (CMC) P42224 (related)
H00480 Non-syndromic X-linked mental retardation P50052 (related)
H00775 Familial or sporadic hemiplegic migraine P50993 (related)
H00998 Alternating hemiplegia of childhood P50993 (related)
H01210 Hypomagnesemia P54710 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00228 Thalassemia P68871 (related)
H00229 Sickle cell anemia (SCA) P68871 (related)
H01296 Hereditary neuropathy with liability to pressure palsies (HNPP) Q01453 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
H00208 Hyperbilirubinemia Q92887 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)

Diseases related to CTD interactions

134 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D001281 Atrial Fibrillation C00003616
C00003617
C00003618
C00003633
D001145 Arrhythmias, Cardiac C00003617
C00003618
C00003633
C00032213
D006331 Heart Diseases C00003617
C00003618
C00003633
D017180 Tachycardia, Ventricular C00003617
C00003618
C00003633
D012640 Seizures C00003617
C00003618
C00003633
D014693 Ventricular Fibrillation C00003617
C00003618
C00003633
D001919 Bradycardia C00003617
C00003618
C00003633
D018879 Ventricular Premature Complexes C00003617
C00003618
C00003633
D006973 Hypertension C00003617
C00003618
C00003633
D006332 Cardiomegaly C00003617
C00003618
C00003633
D006323 Heart Arrest C00003617
C00003618
C00003633
D064420 Drug-Related Side Effects and Adverse Reactions C00003617
C00003618
C00003633
D006333 Heart Failure C00003617
C00003618
D003251 Constriction, Pathologic C00003617
C00003633
D003693 Delirium C00003617
C00003618
D003866 Depressive Disorder C00003617
C00003618
D002318 Cardiovascular Diseases C00003617
C00003618
D009202 Cardiomyopathies C00003617
C00003618
D001282 Atrial Flutter C00003617
C00003618
D003221 Confusion C00003617
C00003618
D009410 Nerve Degeneration C00003618
C00003633
D013610 Tachycardia C00003618
C00003633
D007022 Hypotension C00003617
C00003618
D020925 Hypoxia-Ischemia, Brain C00003617
C00003633
D053609 Lethargy C00003617
C00003618
D006327 Heart Block C00003618
C00003633
D001927 Brain Diseases C00003618
C00003633
D002037 Bundle-Branch Block C00003617
C00003618
D010554 Personality Disorders C00003617
C00003618
C535438 Bidirectional tachycardia C00003617
C00003618
D018487 Ventricular Dysfunction, Left C00003617
C00003618
D054537 Atrioventricular Block C00003617
C00003618
D012804 Sick Sinus Syndrome C00003617
C00003618
D012848 Sinoatrial Block C00003617
C00003618
D013617 Tachycardia, Supraventricular C00003617
C00003618
D018880 Atrial Premature Complexes C00003617
C00003618
D009901 Optic Nerve Diseases C00003618
D014202 Tremor C00003617
D014549 Urinary Incontinence C00003617
D020301 Vasospasm, Intracranial C00003617
D012021 Reflex, Abnormal C00003617
D011660 Pulmonary Heart Disease C00003617
D020258 Neurotoxicity Syndromes C00003617
D015746 Abdominal Pain C00003618
D058186 Acute Kidney Injury C00003618
D000370 Ageusia C00003618
D000743 Anemia, Hemolytic C00003618
D000787 Angina Pectoris C00003618
D000855 Anorexia C00003618
D001259 Ataxia C00003618
D001321 Autistic Disorder C00003618
D001327 Autoimmune Diseases C00003618
D009069 Movement Disorders C00003617
D002311 Cardiomyopathy, Dilated C00003618
D002526 Cerebellar Diseases C00003618
D002598 Chagas Cardiomyopathy C00003618
D002639 Cheyne-Stokes Respiration C00003618
D002819 Chorea C00003618
D003072 Cognition Disorders C00003618
D003117 Color Vision Defects C00003618
D003128 COMA C00003618
D003324 Coronary Artery Disease C00003618
D003329 Coronary Vasospasm C00003618
D003645 Death, Sudden C00003618
D003680 Deglutition Disorders C00003618
D003704 Dementia C00003618
D003967 Diarrhea C00003618
D004244 Dizziness C00003618
D056486 Drug-Induced Liver Injury C00003618
D062787 Drug Overdose C00003618
D004374 Ductus Arteriosus, Patent C00003618
D055154 Dysphonia C00003618
D004417 Dyspnea C00003618
D001068 Eating Disorders C00003618
D004437 Ebstein Anomaly C00003618
D004487 Edema C00003618
D007172 Erectile Dysfunction C00003618
D058447 Eye Pain C00003618
D005221 Fatigue C00003618
D005315 Fetal Diseases C00003618
D006212 Hallucinations C00003618
C537347 Mesenteric vascular disease C00003617
D006505 Hepatitis C00003618
D006947 Hyperkalemia C00003618
D007008 Hypokalemia C00003618
D007232 Infant, Newborn, Diseases C00003618
D007235 Infant, Premature, Diseases C00003618
D007859 Learning Disorders C00003618
D008133 Long QT Syndrome C00003618
D008173 Lung Diseases, Obstructive C00003618
D008275 Magnesium Deficiency C00003618
D008569 Memory Disorders C00003618
D001523 Mental Disorders C00003618
D008944 Mitral Valve Insufficiency C00003618
D019964 Mood Disorders C00003618
D009325 Nausea C00003618
D009369 Neoplasms C00003618
D006530 Hepatorenal Syndrome C00003617
D009759 Nystagmus, Pathologic C00003618
D000857 Olfaction Disorders C00003618
D013921 Thrombocytopenia C00003617
D010146 Pain C00003618
D010259 Paranoid Disorders C00003618
D011596 Psychomotor Disorders C00003618
D011654 Pulmonary Edema C00003618
D051437 Renal Insufficiency C00003618
D012206 Rhabdomyolysis C00003618
D020018 Sexual Dysfunctions, Psychological C00003618
D013375 Substance Withdrawal Syndrome C00003618
D002289 Carcinoma, Non-Small-Cell Lung C00003617
D013612 Tachycardia, Ectopic Atrial C00003618
D013613 Tachycardia, Ectopic Junctional C00003618
D013614 Tachycardia, Paroxysmal C00003618
D016171 Torsades de Pointes C00003618
D014277 Trigeminal Neuralgia C00003618
D018754 Ventricular Dysfunction C00003618
D014786 Vision Disorders C00003618
D014839 Vomiting C00003618
D015431 Weight Loss C00003618
D000014 Abnormalities, Drug-Induced C00003633
D000647 Amnesia C00003633
D001714 Bipolar Disorder C00003633
D001929 Brain Edema C00003633
D020520 Brain Infarction C00003633
D001930 Brain Injuries C00003633
D002303 Cardiac Output, Low C00003633
D006948 Hyperkinesis C00003633
D009336 Necrosis C00003633
D010243 Paralysis C00003633
D012164 Retinal Diseases C00003633
D020182 Sleep Apnea, Central C00003633
D013616 Tachycardia, Sinus C00003633
D014570 Urologic Diseases C00003633
D015837 Vestibular Diseases C00003633