| class name | count |
|---|
| class name | count |
|---|---|
| Aspergillaceae | 6 |
| Pleosporaceae | 4 |
| Clavicipitaceae | 4 |
| br08003 Category | # of metabolite |
|---|
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00016018
|
Dehydrocurvularin
/ Dehydro-curvularin / trans-Dehydrocurvularin / alpha,beta-Dehydrocurvularin |
CHEMBL482050
CHEMBL520014 CHEMBL1643635 |
C013914
|
21 / 19 / 20 |
|
|
|
C00023738
|
trans-Resorcylide
|
|
||||
|
C00023739
|
cis-Resorcylide
|
|
||||
|
C00023958
|
cis-Dehydrocurvularin
|
CHEMBL482050
CHEMBL520014 CHEMBL1643635 |
21 / 19 / 20 |
|
||
|
C00044938
|
Monocillin II
|
|
||||
|
C00045020
|
Pochonin D
|
CHEMBL526127
|
2 / 0 / 1 |
|
||
|
C00045021
|
Pochonin E
/ (-)-Pochonin E |
CHEMBL449441
|
1 / 0 / 1 |
|
||
|
C00045022
|
Pochonin F
|
CHEMBL461398
|
1 / 0 / 1 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q92731 | Estrogen receptor beta | NR3A2 | C00045020 C00045021 C00045022 | 0 / 1 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00016018 C00023958 | 1 / 1 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00016018 C00023958 | 2 / 3 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00016018 C00023958 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00016018 C00023958 | 2 / 0 |
| O75496 | Geminin | Unclassified protein | C00016018 C00023958 | 0 / 0 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00016018 C00023958 | 0 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00016018 C00023958 | 1 / 1 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00016018 C00023958 | 0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00016018 C00023958 | 1 / 1 |
| Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | Enzyme | C00016018 C00023958 | 0 / 0 |
| Q13315 | Serine-protein kinase ATM | Atypical serine/threonine protein kinase PIKK subfamily | C00016018 C00023958 | 1 / 4 |
| P01215 | Glycoprotein hormones alpha chain | Unclassified protein | C00016018 C00023958 | 0 / 3 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00016018 C00023958 | 0 / 0 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00016018 C00023958 | 1 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00016018 C00023958 | 0 / 0 |
| Q6W5P4 | Neuropeptide S receptor | Neuropeptide receptor | C00016018 C00023958 | 1 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00016018 C00023958 | 4 / 3 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00016018 C00023958 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00016018 C00023958 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00016018 C00023958 | 1 / 0 |
| O75030 | Microphthalmia-associated transcription factor | Unclassified protein | C00016018 C00023958 | 4 / 4 |
| P08238 | Heat shock protein HSP 90-beta | Other cytosolic protein | C00045020 | 0 / 0 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #103470 | Albinism, ocular, with sensorineural deafness |
O75030
|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #608584 | Asthma-related traits, susceptibility to, 2 |
Q6W5P4
|
| #208900 | Ataxia-telangiectasia; at |
Q13315
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #614456 | Melanoma, cutaneous malignant, susceptibility to, 8; cmm8 |
O75030
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #103500 | Tietz syndrome |
O75030
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #193510 | Waardenburg syndrome, type 2a; ws2a |
O75030
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
| KEGG | name | UniProt |
|---|---|---|
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H00038 | Malignant melanoma |
O75030
(related)
O75030 (marker) |
| H00169 | Ocular albinism |
O75030
(related)
|
| H00759 | Waardenburg syndrome (WS) |
O75030
(related)
|
| H01187 | Tietz syndrome |
O75030
(related)
|
| H00081 | Hashimoto's thyroiditis |
P01215
(marker)
|
| H00082 | Graves' disease |
P01215
(marker)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P01215
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
Q13315
(related)
|
| H00064 | Ataxia telangiectasia (AT) |
Q13315
(related)
|
| H00094 | DNA repair defects |
Q13315
(related)
|
| H00848 | Ataxia with ocular apraxia (AOA) |
Q13315
(related)
|
| H00026 | Endometrial Cancer |
Q92731
(marker)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|